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Questions and Answers
How does the virus continue to replicate during this phase?
How does the virus continue to replicate during this phase?
At a reduced rate, without causing significant damage to the host cell
What are defective-interfering particles, and how do they affect replication?
What are defective-interfering particles, and how do they affect replication?
Defective-interfering particles interfere with the replication of fully infectious virus particles.
What does the downregulation of viral gene expression allow the virus to do within the host cell?
What does the downregulation of viral gene expression allow the virus to do within the host cell?
Ensures its long-term survival and the potential for transmission to other hosts.
How is Lymphocytic Choriomeningitis Virus primarily transmitted to humans?
How is Lymphocytic Choriomeningitis Virus primarily transmitted to humans?
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What are two major opportunities for zoonotic transmission of Lymphocytic Choriomeningitis Virus?
What are two major opportunities for zoonotic transmission of Lymphocytic Choriomeningitis Virus?
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What kind of threat does Lymphocytic Choriomeningitis Virus pose to researchers and laboratory workers?
What kind of threat does Lymphocytic Choriomeningitis Virus pose to researchers and laboratory workers?
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Which rodent species is the reservoir host for Chapare virus?
Which rodent species is the reservoir host for Chapare virus?
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Where was Sabia virus isolated from a fatal case of hemorrhagic fever?
Where was Sabia virus isolated from a fatal case of hemorrhagic fever?
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Which South American hemorrhagic fever virus has an uncertain association with human disease?
Which South American hemorrhagic fever virus has an uncertain association with human disease?
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In what year was Chapare virus isolated following a small cluster of cases near Cochabamba, Bolivia?
In what year was Chapare virus isolated following a small cluster of cases near Cochabamba, Bolivia?
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How do Junin and Machupo viruses behave in their reservoir rodent hosts compared to lymphocytic choriomeningitis and Lassa viruses?
How do Junin and Machupo viruses behave in their reservoir rodent hosts compared to lymphocytic choriomeningitis and Lassa viruses?
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What is the reservoir host for Sabia virus?
What is the reservoir host for Sabia virus?
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What is the reservoir of the Lassa virus?
What is the reservoir of the Lassa virus?
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Describe the clinical presentation of Lassa fever in humans.
Describe the clinical presentation of Lassa fever in humans.
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Where was the Lassa virus first identified?
Where was the Lassa virus first identified?
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How is Lassa fever transmitted to humans?
How is Lassa fever transmitted to humans?
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What are some of the complications associated with severe cases of Lassa fever?
What are some of the complications associated with severe cases of Lassa fever?
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How is Lassa fever diagnosed?
How is Lassa fever diagnosed?
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What is the main target of lymphocytic choriomeningitis virus in the initial stages of infection?
What is the main target of lymphocytic choriomeningitis virus in the initial stages of infection?
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Which type of T cells are responsible for the central nervous system lesions in lymphocytic choriomeningitis virus infection?
Which type of T cells are responsible for the central nervous system lesions in lymphocytic choriomeningitis virus infection?
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What is the most common method for serosurveillance of lymphocytic choriomeningitis virus infection in laboratory rodents?
What is the most common method for serosurveillance of lymphocytic choriomeningitis virus infection in laboratory rodents?
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Which cells are particularly useful for cultivating lymphocytic choriomeningitis virus?
Which cells are particularly useful for cultivating lymphocytic choriomeningitis virus?
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What type of immunity is developed upon exposure of adult, immunocompetent animals to lymphocytic choriomeningitis virus?
What type of immunity is developed upon exposure of adult, immunocompetent animals to lymphocytic choriomeningitis virus?
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What are the most common control methods used for lymphocytic choriomeningitis in laboratory mice and hamsters?
What are the most common control methods used for lymphocytic choriomeningitis in laboratory mice and hamsters?
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What is presumed to be key to recovery and protection against reinfection from Lassa virus?
What is presumed to be key to recovery and protection against reinfection from Lassa virus?
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Which antiviral drug may be beneficial in some patients with Lassa fever?
Which antiviral drug may be beneficial in some patients with Lassa fever?
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What is a factor contributing to the increasing occurrence of the Lassa virus in West Africa?
What is a factor contributing to the increasing occurrence of the Lassa virus in West Africa?
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What has shown promise in protecting nonhuman primates from Lassa fever?
What has shown promise in protecting nonhuman primates from Lassa fever?
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When is rodent elimination particularly valuable in villages to prevent Lassa fever?
When is rodent elimination particularly valuable in villages to prevent Lassa fever?
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Where was the Lujo virus first identified in 2008?
Where was the Lujo virus first identified in 2008?
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