Virology: Viral Morphology and Capsid Structure
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Questions and Answers

What is the composition of a virion?

Protein shell (capsid) plus the entire virus (sometimes including the viral envelope)

Define nucleocapsid.

The associated complex of the nucleic acid core and the capsid proteins, synonymous to virion.

What are the components found in the viral envelope?

Mixtures of neutral lipids, phospholipids, glycolipids, and specific proteins.

What is the difference between a naked capsid and an enveloped virus?

<p>A naked capsid is a complete virion with no surrounding membrane, while an enveloped virus has a cellular type membrane surrounding the nucleocapsid.</p> Signup and view all the answers

What is a viroid?

<p>A less complex and smaller infectious agent consisting of short naked fragments of SS RNA.</p> Signup and view all the answers

What are prions and which diseases in animals are associated with them?

<p>Prions are small infectious proteins causing fatal neurologic diseases. Diseases associated with prions include Scrapie, BSE (mad cow disease), and Kuru/Creutzfeldt-Jacob (C-J) disease.</p> Signup and view all the answers

What are spongiform encephalopathies and how are they characterized?

<p>Spongiform encephalopathies are diseases where the brain becomes riddled with holes, resembling a sponge. They are characterized by loss of coordination, dementia, and other neurologic symptoms.</p> Signup and view all the answers

Explain the connection between Kuru and ritualistic cannibalism in Papua, New Guinea.

<p>Kuru was common among natives of Papua, New Guinea, where women and children ate prion-infected human brains as part of a traditional burial custom known as ritualistic cannibalism.</p> Signup and view all the answers

Which types of cancers are associated with Epstein Barr Virus (EBV)?

<p>EBV causes Nasopharyngeal cancer, Burkitt's lymphoma, and B-cell Lymphoma.</p> Signup and view all the answers

What are the three categories of bacteriophages based on their shape?

<p>The three categories are icosahedron, filamentous, and complex bacteriophage.</p> Signup and view all the answers

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