Virology: Herpesviruses
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Questions and Answers

How many human pathogens are present in the herpesvirus family?

  • Five
  • Seven
  • Four
  • Six (correct)

What is the shape of herpesviruses?

  • Helical
  • Icosahedral (correct)
  • Filamentous
  • Spherical

Which of the following is a risk factor for reactivation of Varicella Zoster Virus?

  • Having a healthy diet
  • Being in a crowded area
  • Fifth or sixth decade of life (correct)
  • Taking too much vitamin C

What is unique about the way herpesviruses obtain their envelope?

<p>It is obtained by budding from the nuclear membrane (C)</p> Signup and view all the answers

What is the purpose of antiviral medications such as acyclovir in Varicella Zoster Virus treatment?

<p>To prevent complications in immunocompromised patients (C)</p> Signup and view all the answers

What is a characteristic of herpesvirus replication?

<p>It occurs in the nucleus (A)</p> Signup and view all the answers

How is Varicella Zoster Virus typically transmitted?

<p>Through respiratory droplets and contact with blisters (C)</p> Signup and view all the answers

What is a result of the latency of herpesviruses?

<p>The virus can reactivate and cause disease (A)</p> Signup and view all the answers

What is a common method of transmission for HSV-1 and HSV-2?

<p>Saliva or direct contact with virus from the vesicle (B)</p> Signup and view all the answers

What is the typical clinical presentation of shingles?

<p>Painful vesicles along the course of a sensory nerve (B)</p> Signup and view all the answers

When do people with chickenpox become infectious?

<p>One to two days before the rash appears (D)</p> Signup and view all the answers

What is postherpetic neuralgia?

<p>Severe nerve pain (B)</p> Signup and view all the answers

What is the primary site of latent infection for HSV-1?

<p>Trigeminal ganglion (A)</p> Signup and view all the answers

What triggers reactivation of the virus in nerve cells and recurrence of vesicles?

<p>All of the above (D)</p> Signup and view all the answers

What is the primary difference between HSV-1 and HSV-2 infections?

<p>HSV-1 generally occurs above the waist, while HSV-2 occurs below the waist (C)</p> Signup and view all the answers

What is a common systemic effect of HSV-2 infections?

<p>All of the above (D)</p> Signup and view all the answers

What is the primary method of diagnosis for encephalitis caused by HSV?

<p>PCR on CSF (D)</p> Signup and view all the answers

What is the primary route of transmission for neonatal herpes?

<p>Infection during passage through infected birth canal (A)</p> Signup and view all the answers

What is recommended to avoid secondary bacterial infection in shingles?

<p>Maintaining good hygiene and daily cleaning of skin with warm water (A)</p> Signup and view all the answers

What is the recommended vaccine for adults 50 years and older to prevent shingles?

<p>Shingrix (subunit vaccine) (D)</p> Signup and view all the answers

What is the recommended treatment for life-threatening EBV infections?

<p>Acyclovir in high doses (C)</p> Signup and view all the answers

What is associated with Burkitt's lymphoma and nasopharyngeal carcinoma?

<p>EBV (D)</p> Signup and view all the answers

What may increase the risk of secondary infection in shingles?

<p>Scratching (D)</p> Signup and view all the answers

What is not necessary for uncomplicated infectious mononucleosis?

<p>Antiviral therapy (B)</p> Signup and view all the answers

What is the effect of CMV on immunocompromised patients?

<p>It causes pneumonia and other diseases. (C)</p> Signup and view all the answers

What is the primary mode of transmission of CMV?

<p>Through saliva, urine, sexual, parenteral, placenta, within the birth canal, breast milk, blood transfusions and organ transplants. (B)</p> Signup and view all the answers

What is the treatment for CMV-caused pneumonia and retinitis?

<p>Ganciclovir (C)</p> Signup and view all the answers

What is the disease caused by the Smallpox virus?

<p>Smallpox (C)</p> Signup and view all the answers

What is the characteristic of the lesions caused by Molluscum contagiosum virus?

<p>Pinkish, papular with an umbilicated center (A)</p> Signup and view all the answers

What is the diagnosis of Molluscum contagiosum virus infection typically made by?

<p>Clinically (A)</p> Signup and view all the answers

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