Virology: Herpesviruses
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Questions and Answers

How many human pathogens are present in the herpesvirus family?

  • Five
  • Seven
  • Four
  • Six (correct)

    • What is the shape of herpesviruses?

  • Helical
  • Icosahedral (correct)
  • Filamentous
  • Spherical

    • Which of the following is a risk factor for reactivation of Varicella Zoster Virus?

  • Having a healthy diet
  • Being in a crowded area
  • Fifth or sixth decade of life (correct)
  • Taking too much vitamin C

    • What is unique about the way herpesviruses obtain their envelope?

    <p>It is obtained by budding from the nuclear membrane</p> Signup and view all the answers

    What is the purpose of antiviral medications such as acyclovir in Varicella Zoster Virus treatment?

    <p>To prevent complications in immunocompromised patients</p> Signup and view all the answers

    What is a characteristic of herpesvirus replication?

    <p>It occurs in the nucleus</p> Signup and view all the answers

    How is Varicella Zoster Virus typically transmitted?

    <p>Through respiratory droplets and contact with blisters</p> Signup and view all the answers

    What is a result of the latency of herpesviruses?

    <p>The virus can reactivate and cause disease</p> Signup and view all the answers

    What is a common method of transmission for HSV-1 and HSV-2?

    <p>Saliva or direct contact with virus from the vesicle</p> Signup and view all the answers

    What is the typical clinical presentation of shingles?

    <p>Painful vesicles along the course of a sensory nerve</p> Signup and view all the answers

    When do people with chickenpox become infectious?

    <p>One to two days before the rash appears</p> Signup and view all the answers

    What is postherpetic neuralgia?

    <p>Severe nerve pain</p> Signup and view all the answers

    What is the primary site of latent infection for HSV-1?

    <p>Trigeminal ganglion</p> Signup and view all the answers

    What triggers reactivation of the virus in nerve cells and recurrence of vesicles?

    <p>All of the above</p> Signup and view all the answers

    What is the primary difference between HSV-1 and HSV-2 infections?

    <p>HSV-1 generally occurs above the waist, while HSV-2 occurs below the waist</p> Signup and view all the answers

    What is a common systemic effect of HSV-2 infections?

    <p>All of the above</p> Signup and view all the answers

    What is the primary method of diagnosis for encephalitis caused by HSV?

    <p>PCR on CSF</p> Signup and view all the answers

    What is the primary route of transmission for neonatal herpes?

    <p>Infection during passage through infected birth canal</p> Signup and view all the answers

    What is recommended to avoid secondary bacterial infection in shingles?

    <p>Maintaining good hygiene and daily cleaning of skin with warm water</p> Signup and view all the answers

    What is the recommended vaccine for adults 50 years and older to prevent shingles?

    <p>Shingrix (subunit vaccine)</p> Signup and view all the answers

    What is the recommended treatment for life-threatening EBV infections?

    <p>Acyclovir in high doses</p> Signup and view all the answers

    What is associated with Burkitt's lymphoma and nasopharyngeal carcinoma?

    <p>EBV</p> Signup and view all the answers

    What may increase the risk of secondary infection in shingles?

    <p>Scratching</p> Signup and view all the answers

    What is not necessary for uncomplicated infectious mononucleosis?

    <p>Antiviral therapy</p> Signup and view all the answers

    What is the effect of CMV on immunocompromised patients?

    <p>It causes pneumonia and other diseases.</p> Signup and view all the answers

    What is the primary mode of transmission of CMV?

    <p>Through saliva, urine, sexual, parenteral, placenta, within the birth canal, breast milk, blood transfusions and organ transplants.</p> Signup and view all the answers

    What is the treatment for CMV-caused pneumonia and retinitis?

    <p>Ganciclovir</p> Signup and view all the answers

    What is the disease caused by the Smallpox virus?

    <p>Smallpox</p> Signup and view all the answers

    What is the characteristic of the lesions caused by Molluscum contagiosum virus?

    <p>Pinkish, papular with an umbilicated center</p> Signup and view all the answers

    What is the diagnosis of Molluscum contagiosum virus infection typically made by?

    <p>Clinically</p> Signup and view all the answers

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