Viral Infections and Hyperthermia Quiz
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Questions and Answers

What is the primary effect of ionizing radiation on rapidly proliferating cells?

  • It kills the cells (correct)
  • It increases cell mutation rates
  • It promotes cell growth
  • It enhances cell division
  • Which of the following is a consequence of radiation exposure during pregnancy?

  • Decreased chances of birth defects
  • Increased likelihood of abortions (correct)
  • Higher chances of normal birth outcomes
  • Improved fetal health
  • What percentage of women who were pregnant during the atomic bomb explosions at Hiroshima and Nagasaki gave birth to children with severe birth defects involving the central nervous system?

  • 10%
  • 75%
  • 50%
  • 25% (correct)
  • In addition to being teratogenic, what other significant effect does radiation have on cells?

    <p>It is a mutagenic agent (A)</p> Signup and view all the answers

    What is a potential outcome of genetic alteration of germ cells due to ionizing radiation?

    <p>Subsequent malformations (C)</p> Signup and view all the answers

    What defines a syndrome in the context of abnormalities?

    <p>A group of anomalies with a specific common cause. (B)</p> Signup and view all the answers

    Which of the following statements correctly describes an association?

    <p>An association is when anomalies appear together more frequently than by chance alone. (D)</p> Signup and view all the answers

    What is a key characteristic that differentiates a syndrome from an association?

    <p>Syndromes have known causes, while associations do not determine causation. (D)</p> Signup and view all the answers

    Which of the following is an example of an association?

    <p>VACTERL association. (B)</p> Signup and view all the answers

    Why is recognizing anomalies in an association important?

    <p>It promotes the search for other abnormalities within the group. (A)</p> Signup and view all the answers

    What percentage of birth defect cases have an unknown cause?

    <p>40% to 60% (B)</p> Signup and view all the answers

    How do environmental factors contribute to the occurrence of birth defects?

    <p>They account for about 10% of cases. (C)</p> Signup and view all the answers

    What is the relationship between the number of minor anomalies and the chance of having major malformations in infants?

    <p>Three or more minor anomalies result in a 20% chance. (C)</p> Signup and view all the answers

    What is the primary cause of malformations during fetal development?

    <p>Environmental and/or genetic factors during organ formation (D)</p> Signup and view all the answers

    What percentage of newborns are affected by minor anomalies?

    <p>15% (B)</p> Signup and view all the answers

    In cases of twinning, what percentage contributes to birth defects?

    <p>0.5% to 1% (D)</p> Signup and view all the answers

    Which of the following is an example of a deformation?

    <p>Clubfeet resulting from compression in the amniotic cavity (A)</p> Signup and view all the answers

    Which infectious agent is associated with significant birth defects and often shows no symptoms in the mother?

    <p>Cytomegalovirus (A)</p> Signup and view all the answers

    What characterizes disruptions in fetal development?

    <p>They involve morphological alterations of already formed structures. (A)</p> Signup and view all the answers

    During which weeks of gestation do most malformations typically originate?

    <p>Third to eighth week (D)</p> Signup and view all the answers

    What percentage of women are currently immune to Rubella, reducing the incidence of related birth defects?

    <p>85% (A)</p> Signup and view all the answers

    Which of the following viruses is NOT listed as a cause of birth defects?

    <p>Papillomavirus (D)</p> Signup and view all the answers

    Which condition would best be classified as a disruption?

    <p>A limb absence from amniotic band syndrome (A)</p> Signup and view all the answers

    Which birth defect-causing virus can lead to severe mental impairment, such as mental retardation, due to its effects on the fetus?

    <p>Cytomegalovirus (A)</p> Signup and view all the answers

    What was a significant factor in reducing birth defects caused by Rubella?

    <p>Vaccine and serum antibody detection (D)</p> Signup and view all the answers

    Which viral infections have been associated with malformations following maternal infection?

    <p>Measles, Mumps, and Hepatitis (B)</p> Signup and view all the answers

    What is a characteristic feature of fetal infection due to Toxoplasmosis?

    <p>Calcifications (A)</p> Signup and view all the answers

    Which of the following sources can carry Toxoplasmosis gondii?

    <p>Poorly cooked meat (C)</p> Signup and view all the answers

    What is the general rate of malformations indicated by prospective studies following maternal infections with certain viral agents?

    <p>Low or nonexistent malformation rate (D)</p> Signup and view all the answers

    Which condition is NOT mentioned as causing birth defects?

    <p>Hepatitis (D)</p> Signup and view all the answers

    What is the primary field of study concerned with birth defects?

    <p>Teratology and dysmorphology (A)</p> Signup and view all the answers

    What percentage of liveborn infants are identified with major structural anomalies?

    <p>2% to 3% (C)</p> Signup and view all the answers

    What is the significance of birth defects in infant mortality?

    <p>They are the leading cause of infant mortality. (C)</p> Signup and view all the answers

    What role do dysmorphologists typically play in clinical settings?

    <p>They work in clinical genetics departments. (A)</p> Signup and view all the answers

    In addition to infant mortality, what other impact do birth defects have?

    <p>They are the fifth leading cause of years of potential life lost before age 65. (A)</p> Signup and view all the answers

    What makes it challenging to assess the role of chemical agents in human abnormalities?

    <p>The reliance on mothers' memory for exposure history and the high number of drugs taken. (B)</p> Signup and view all the answers

    Which drug is specifically mentioned as having a causal relationship with meromelia?

    <p>Thalidomide (A)</p> Signup and view all the answers

    Why might the association between common birth defects and drug exposure be overlooked?

    <p>Defects like cleft lip or heart malformations occur frequently. (B)</p> Signup and view all the answers

    What kind of studies are primarily used to assess the impact of pharmaceutical drugs on pregnant women?

    <p>Retrospective studies. (D)</p> Signup and view all the answers

    What is a consequence of the widespread use of chemical agents during pregnancy?

    <p>Few drugs have been positively identified as teratogenic. (B)</p> Signup and view all the answers

    What primarily influences susceptibility to teratogenesis in a conceptus?

    <p>The genotype of the conceptus and maternal genome interactions (B)</p> Signup and view all the answers

    During which period of gestation is the conceptus most sensitive to teratogenic exposure?

    <p>Third to eighth weeks of gestation (C)</p> Signup and view all the answers

    What is a key factor in the manifestations of abnormal development caused by teratogens?

    <p>Dose and duration of exposure to the teratogen (B)</p> Signup and view all the answers

    How do teratogens typically affect developing cells and tissues?

    <p>They initiate abnormal embryogenesis through various mechanisms (D)</p> Signup and view all the answers

    Which of the following is NOT a manifestation of abnormal development caused by teratogens?

    <p>Fatigue in the mother (D)</p> Signup and view all the answers

    Study Notes

    Other Viral Infections and Hyperthermia

    • Malformations from maternal infections with measles, mumps, hepatitis, poliomyelitis, echovirus, coxsackie virus, and influenza virus have been described.
    • Prospective studies show the rate of malformation after exposure to these agents is low.
    • Toxoplasmosis and syphilis cause birth defects.
    • Poorly cooked meat from domestic animals, especially cats, and feces in contaminated soil can carry the protozoan parasite Toxoplasma gondii.
    • A characteristic feature of fetal toxoplasmosis infection is calcification.

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    Description

    This quiz covers the impact of various maternal infections on fetal development, including measles, mumps, and toxoplasmosis. Learn about the rates of malformation and the transmission routes of harmful pathogens. Test your knowledge on how these infections can lead to birth defects and the importance of proper food handling.

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