Viral Evolution and the RNA to DNA Transition Quiz
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Questions and Answers

Which step comes after attachment in the virus entry process?

  • Penetration
  • Transport
  • Uncoating
  • Entry (correct)

How do enveloped viruses primarily enter the host cell?

  • Formation of syncytia
  • Fusion and fusion of the envelope with the plasma membrane (correct)
  • Passage of viral genome through a channel in the membrane
  • Receptor-mediated endocytosis followed by fusion/fission with an endosome

What is the primary entry mechanism for non-enveloped viruses?

  • Receptor mediated endocytosis followed by rupture of endosomal membrane (correct)
  • Fusion with the plasma membrane
  • Formation of syncytia
  • Passage of viral genome through a channel in the membrane

What is the purpose of virological synapses in cell-to-cell transmission?

<p>Allow passage of enveloped viruses from one cell to another (C)</p> Signup and view all the answers

What is the first step for virus entry into the host cell?

<p>Attachment (A)</p> Signup and view all the answers

What do attachment factors/adhesion receptors do?

<p>Involved in binding of virion to cell but not uptake (C)</p> Signup and view all the answers

What triggers macropinocytosis in virus entry?

<p>Exploiting cell signaling (A)</p> Signup and view all the answers

What is the purpose of low pH in virus entry?

<p>Triggers passage from endosomes to the cytosol (C)</p> Signup and view all the answers

What is the role of entry receptors in virus entry?

<p>Play an active role in conformational changes, cell signaling, endocytosis, etc. (A)</p> Signup and view all the answers

What is the primary mechanism for enveloped viruses to enter the host cell?

<p>Fusion of envelope with cell membrane (D)</p> Signup and view all the answers

What is the purpose of syncytia formation in virus transmission?

<p>Results from fusion of infected and uninfected cells (C)</p> Signup and view all the answers

What is the purpose of receptor-mediated endocytosis in virus entry?

<p>Viruses enter the cell (A)</p> Signup and view all the answers

What is a key characteristic of viroids and RNA viruses?

<p>They may have originated in the RNA world (D)</p> Signup and view all the answers

What is the main function of the mission of viruses?

<p>To transport the viral genome from an infected cell to uninfected cell (A)</p> Signup and view all the answers

What is the potential origin of small and medium-sized DNA viruses?

<p>Independently replicating genetic elements in cells (A)</p> Signup and view all the answers

What is the role of reverse transcriptase in the transition to the DNA-based world?

<p>To make DNA copies of RNA (D)</p> Signup and view all the answers

What is the likely fate of genes that overlap with cellular genes in large DNA viruses?

<p>They were lost due to similar functions (D)</p> Signup and view all the answers

What is the main requirement for viruses to replicate?

<p>They need host cells (D)</p> Signup and view all the answers

What is the key difference between DNA and RNA in the context of stability?

<p>DNA is much more stable than RNA (C)</p> Signup and view all the answers

What is the primary function of viral proteins in large DNA viruses?

<p>Stimulate DNA replication enzymes in the host (B)</p> Signup and view all the answers

What is the significance of the production of deoxyribonucleotides from ribonucleotides in the transition to the DNA-based world?

<p>It allowed for the creation of DNA copies of RNA (C)</p> Signup and view all the answers

What is the primary role of viruses in evading host defenses?

<p>To 'evade' host cell defense barriers (C)</p> Signup and view all the answers

What is the likely origin of large DNA viruses?

<p>They could have evolved from cellular forms (C)</p> Signup and view all the answers

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