4 Questions
Which method is feasible for detecting viral nucleic acids in acute infection?
Detection of viral nucleic acids by a specific probe (DNA or RNA probe)
What is the specimen of choice for serological diagnosis?
Serum
Which method detects the viral agent in the clinical specimen using cell culture systems?
Virus isolation (growth in cell culture systems)
When is the production of detectable antibody for serological diagnosis feasible in acute infection?
10-30 days
Study Notes
Viral Nucleic Acid Detection
- PCR (Polymerase Chain Reaction) or Nucleic Acid Amplification Test (NAAT) is feasible for detecting viral nucleic acids in acute infection
Specimen of Choice for Serological Diagnosis
- Serum is the specimen of choice for serological diagnosis
Cell Culture Systems
- Virus Isolation detects the viral agent in the clinical specimen using cell culture systems
Production of Detectable Antibody
- Production of detectable antibody for serological diagnosis is feasible in acute infection around 7-10 days after symptom onset or 10-14 days after infection
Test your knowledge of viral diagnosis methods with this quiz! Explore electron microscopy, virus isolation, antigen and nucleic acid detection, and indirect serological diagnosis. See how much you know about detecting viral agents in clinical specimens.
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