Ventilation and Respiration Quiz

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30 Questions

Which of the following is the definition of respiration?

The process in living organisms involving energy production, typically with intake of oxygen and release of CO2 from oxidation of complex organic substances

What is the measure of gas exchange efficiency called?

VD/VT ratio

What is the anatomical dead space volume?

1mL/body weight

What is the definition of hyperpnea?

The increase in depth and rate of breathing

What is the definition of 'ventilatory drift' and its function?

The exchange of air

What are the factors that affect ventilation during exercise?

Work rate, fitness level, RBCs amount

What is the tidal volume responsible for during exercise?

The initial increase in minute ventilation

Why don't we take a big breath every time?

Due to time

What is the triphasic response?

The three phases of response

What is the formula for minute ventilation (VE)?

Frequency * tidal volume

Which of the following factors does NOT affect hemoglobin binding to oxygen?

Partial pressure of carbon dioxide (PCO2)

What is the primary function of peripheral chemoreceptors?

Detect hypoxia

Where are the central chemoreceptors located?

Brain

What is the formula for alveolar ventilation?

VA = (VT - VD) * frequency

What is the primary function of bronchodilation?

Decrease resistance in airways with exercise

What is the normal blood pH at rest?

7.4

What is the primary function of the Haldane effect?

Increase carbon dioxide binding to hemoglobin

What is the primary function of the Bohr effect?

Enhance oxygen offloading from hemoglobin

What is the primary source of H+ ions in the blood?

Lactic acid and carbonic acid

What is the primary function of the bicarbonate buffering system?

Transport carbon dioxide in the blood

Which of the following is true about ventilation during exercise?

Ventilation has break points where it increases faster

What does an increase in tidal volume cause in terms of the VD/VT ratio?

Increases the VD/VT ratio

How does the A-a (alveolar to arterial) PO2 difference change during incremental exercise?

The A-a PO2 difference remains constant

What happens to alveolar ventilation during incremental exercise?

Alveolar ventilation follows minute ventilation

At what intensity of max exercise does the gradient for oxygen into the blood increase?

80%

What happens to venous blood saturation as workload increases during incremental exercise?

Venous blood saturation decreases

What happens to O2 levels in the muscle during incremental exercise?

O2 levels plateau around 50%

What happens to O2 extraction from blood as work rate increases during incremental exercise?

O2 extraction remains constant

What is the definition of exercise-induced arterial hypoxemia (EIAH)?

Condition when arterial blood oxygen is severely reduced

What is considered a severe case of exercise-induced arterial hypoxemia (EIAH)?

PaO2 reduced by 4% SaO2

Study Notes

Respiration and Ventilation

  • Respiration is the process of taking oxygen into the body and removing carbon dioxide.

Gas Exchange Efficiency

  • The measure of gas exchange efficiency is called the respiratory exchange ratio (RER).

Anatomical Dead Space Volume

  • The anatomical dead space volume is the volume of air that does not participate in gas exchange, approximately 150 mL in a healthy adult.

Hyperpnea

  • Hyperpnea is a state of increased ventilation in response to increased oxygen demand, such as during exercise.

Ventilatory Drift

  • Ventilatory drift is the gradual increase in ventilation over time during prolonged exercise, serving to compensate for the increasing acidity of the blood.

Factors Affecting Ventilation During Exercise

  • Factors that affect ventilation during exercise include the intensity and duration of exercise, fitness level, and environmental conditions.

Tidal Volume

  • Tidal volume is responsible for increasing ventilation during exercise to meet the increased oxygen demand.

Why We Don't Take a Big Breath Every Time

  • We don't take a big breath every time because the brain regulates breathing to match the body's metabolic demands, and taking a big breath would be inefficient.

Triphasic Response

  • The triphasic response is a three-phase response to exercise, consisting of an initial rapid increase in ventilation, a slow increase, and finally a plateau.

Minute Ventilation (VE)

  • The formula for minute ventilation (VE) is VE = Respiratory Rate (RR) x Tidal Volume (VT).

Factors that Do Not Affect Hemoglobin Binding to Oxygen

  • Temperature does not affect hemoglobin binding to oxygen.

Peripheral Chemoreceptors

  • The primary function of peripheral chemoreceptors is to detect changes in arterial oxygen and carbon dioxide levels and send signals to the brain to adjust ventilation accordingly.

Central Chemoreceptors

  • Central chemoreceptors are located in the brain and respond to changes in cerebrospinal fluid pH.

Alveolar Ventilation

  • The formula for alveolar ventilation is VA = (VT x RR) - (VD x RR), where VA is alveolar ventilation, VT is tidal volume, RR is respiratory rate, and VD is anatomical dead space volume.

Bronchodilation

  • The primary function of bronchodilation is to increase airflow into the lungs by relaxing airway smooth muscle.

Normal Blood pH at Rest

  • The normal blood pH at rest is approximately 7.4.

Haldane Effect

  • The primary function of the Haldane effect is to facilitate the exchange of oxygen and carbon dioxide between the blood and lungs.

Bohr Effect

  • The primary function of the Bohr effect is to facilitate the release of oxygen from hemoglobin to the tissues.

Source of H+ Ions in the Blood

  • The primary source of H+ ions in the blood is the metabolism of glucose and other nutrients.

Bicarbonate Buffering System

  • The primary function of the bicarbonate buffering system is to regulate blood pH by balancing the concentration of bicarbonate and hydrogen ions.

Ventilation During Exercise

  • Ventilation increases during exercise to meet the increased oxygen demand, and the VD/VT ratio decreases.

Tidal Volume and VD/VT Ratio

  • An increase in tidal volume causes a decrease in the VD/VT ratio.

A-a PO2 Difference During Exercise

  • The A-a PO2 difference increases during incremental exercise due to the increased oxygen demand.

Alveolar Ventilation During Exercise

  • Alveolar ventilation increases during incremental exercise to meet the increased oxygen demand.

Gradient for Oxygen into the Blood

  • The gradient for oxygen into the blood increases at an intensity of approximately 60-70% of maximum exercise.

Venous Blood Saturation During Exercise

  • Venous blood saturation decreases as workload increases during incremental exercise.

Oxygen Levels in Muscle During Exercise

  • Oxygen levels in the muscle decrease as workload increases during incremental exercise.

Oxygen Extraction from Blood

  • Oxygen extraction from blood increases as work rate increases during incremental exercise.

Exercise-Induced Arterial Hypoxemia (EIAH)

  • Exercise-induced arterial hypoxemia (EIAH) is a state of reduced arterial oxygen saturation during exercise, usually occurring at high intensities.

Severe Case of EIAH

  • A severe case of EIAH is defined as an arterial oxygen saturation of less than 80%.

Test your knowledge on ventilation and respiration with this quiz! Explore concepts such as aerobic energy production, the definition of respiration, and the exchange of air. Don't miss out on understanding the importance of oxygen intake during exercise for energy production.

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