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Questions and Answers
What causes the VD/VT ratio to increase?
What causes the VD/VT ratio to increase?
- Increase in tidal volume (correct)
- Increase in respiratory rate
- Decrease in tidal volume
- Decrease in respiratory rate
What happens to the A-a (alveolar to arterial) PO2 difference during incremental exercise?
What happens to the A-a (alveolar to arterial) PO2 difference during incremental exercise?
- It fluctuates
- It increases (correct)
- It decreases
- It remains constant
What happens to the oxygen levels in muscle around 50% of maximal work rate?
What happens to the oxygen levels in muscle around 50% of maximal work rate?
- Oxygen levels plateau (correct)
- Oxygen levels fluctuate
- Oxygen levels decrease
- Oxygen levels increase
What is the effect of higher intensity exercise on arterial CO2 levels?
What is the effect of higher intensity exercise on arterial CO2 levels?
What is the atmospheric pressure at sea level in mm Hg?
What is the atmospheric pressure at sea level in mm Hg?
What happens to the O2 mm Hg levels from gradients to travel from atmosphere to mitochondria?
What happens to the O2 mm Hg levels from gradients to travel from atmosphere to mitochondria?
What is the definition of Exercise-induced arterial hypoxemia (EIAH)?
What is the definition of Exercise-induced arterial hypoxemia (EIAH)?
What happens to the O2 levels in arterial and alveolar PO2 at maximal exercise compared to rest?
What happens to the O2 levels in arterial and alveolar PO2 at maximal exercise compared to rest?
What happens to the mean capillary and Mb(myoglobular) O2 levels at rest compared to maximal exercise?
What happens to the mean capillary and Mb(myoglobular) O2 levels at rest compared to maximal exercise?
What is the effect of altitude on atmospheric pressure?
What is the effect of altitude on atmospheric pressure?
What is the definition of hyperpnea?
What is the definition of hyperpnea?
What is the definition of 'ventilatory drift'?
What is the definition of 'ventilatory drift'?
What is the measure of gas exchange efficiency?
What is the measure of gas exchange efficiency?
What is the primary factor responsible for the initial increase in minute ventilation?
What is the primary factor responsible for the initial increase in minute ventilation?
What are the three factors that influence ventilation during exercise?
What are the three factors that influence ventilation during exercise?
What is the function of 'ventilatory drift' after a period of exercise?
What is the function of 'ventilatory drift' after a period of exercise?
What is the physiological dead space primarily due to?
What is the physiological dead space primarily due to?
What is the approximate percentage of oxygen in the room?
What is the approximate percentage of oxygen in the room?
What is the definition of respiration?
What is the definition of respiration?
What is the formula for minute ventilation (VE)?
What is the formula for minute ventilation (VE)?
What is the formula for alveolar ventilation (VA)?
What is the formula for alveolar ventilation (VA)?
What is the function of peripheral chemoreceptors?
What is the function of peripheral chemoreceptors?
What does the oxyhemoglobin dissociation curve represent?
What does the oxyhemoglobin dissociation curve represent?
What is the effect of a left shift in the oxyhemoglobin dissociation curve?
What is the effect of a left shift in the oxyhemoglobin dissociation curve?
Where does the majority of CO2 transport occur in the blood?
Where does the majority of CO2 transport occur in the blood?
What does the term 'Bohr effect' refer to?
What does the term 'Bohr effect' refer to?
What does the a-vO2 (arterial venous oxygen) difference indicate?
What does the a-vO2 (arterial venous oxygen) difference indicate?
What is the primary function of hyperpnea?
What is the primary function of hyperpnea?
What is the source of H+ in the bicarbonate buffering system?
What is the source of H+ in the bicarbonate buffering system?
What is the effect of increasing ventilation on the acid-base balance?
What is the effect of increasing ventilation on the acid-base balance?
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Study Notes
Respiratory Physiology
- The VD/VT ratio increases due to an increase in physiological dead space and a decrease in alveolar ventilation.
Oxygen Levels and Exercise
- Oxygen levels in muscle decrease around 50% of maximal work rate.
- At maximal exercise, arterial PO2 levels decrease, while alveolar PO2 levels remain relatively constant.
- Mean capillary and myoglobin O2 levels decrease at maximal exercise compared to rest.
Gas Exchange and Respiration
- The atmospheric pressure at sea level is 760 mm Hg.
- Oxygen levels (mm Hg) decrease from the atmosphere to the mitochondria due to the gradient of oxygen partial pressure.
- Exercise-induced arterial hypoxemia (EIAH) is a condition where arterial oxygen levels decrease during exercise.
- Respiration is the process of gas exchange between the atmosphere and the body's cells.
Ventilation and Exercise
- Hyperpnea is an increased rate of ventilation, which occurs during exercise.
- Ventilatory drift is a gradual increase in ventilation during prolonged exercise, which helps to maintain arterial CO2 levels.
- The measure of gas exchange efficiency is the VD/VT ratio.
- The primary factor responsible for the initial increase in minute ventilation is the increase in CO2 production.
- Three factors that influence ventilation during exercise are CO2 production, O2 demand, and temperature regulation.
- The function of ventilatory drift is to maintain a stable CO2 level in the blood.
Blood Transport and Oxygen
- The majority of CO2 transport occurs in the blood in the form of bicarbonate ions.
- The oxyhemoglobin dissociation curve represents the binding of oxygen to hemoglobin.
- A left shift in the oxyhemoglobin dissociation curve indicates increased oxygen binding to hemoglobin.
- The a-vO2 difference indicates the amount of oxygen extracted from the blood by the tissues.
Acid-Base Balance
- The source of H+ in the bicarbonate buffering system is the metabolism of CO2 and water.
- Increasing ventilation helps to restore acid-base balance by increasing the exhalation of CO2.
Formulas
- The formula for minute ventilation (VE) is VE = f x VT, where f is the respiratory frequency and VT is the tidal volume.
- The formula for alveolar ventilation (VA) is VA = f x (VT - VD), where VD is the physiological dead space.
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