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Vaccination History and Innovations

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Questions and Answers

What was the primary goal of Edward Jenner's research into cowpox?

To design a safer method of protection against smallpox. (correct)

To develop vaccines for multiple diseases simultaneously.

To eliminate smallpox by variolation.

To establish a method for the treatment of cowpox.

What does the process of attenuation involve?

Combining multiple pathogens in one vaccination.

Using a live strain of a virus to enhance immune response.

Passing a microorganism through a susceptible host to weaken it. (correct)

Inoculating with a fully virulent strain to build immunity.

Which disease was NOT mentioned as being part of Pasteur's vaccine development?

Rabies

Smallpox (correct)

Anthrax

Plague

How did variolation provide immune protection?

<p>Through the introduction of liquid from smallpox pustules to cause mild disease.</p> Signup and view all the answers

What was a significant advancement made by Pasteur compared to earlier methods of immunization?

<p>He devised a method to create immunity without causing disease.</p> Signup and view all the answers

Study Notes

Early Vaccination Practices

Variolation, an intentional infection method, was used in 11th-century India and China to induce immunity to smallpox.
Liquid from smallpox pustules was applied to healthy individuals, causing a mild form of the disease and conferring protection.

Edward Jenner's Contribution

Edward Jenner sought a safer smallpox prevention method.
He hypothesised that cowpox, similar to smallpox, could offer protection.
He inoculated a patient with cowpox and later exposed him to smallpox.
The patient remained unaffected, confirming the effectiveness of this safer method.

Louis Pasteur's Innovations

Pasteur developed a method to create attenuated vaccines.
Attenuation involves weakening a microorganism's virulence through repeated passages in a susceptible host.
This process created vaccines for multiple diseases like anthrax, plague, yellow fever, rabies, and others.

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Description

Explore the key milestones in vaccination practices, from early methods like variolation to breakthroughs by Edward Jenner and Louis Pasteur. This quiz covers important historical figures and their contributions to immunology and vaccine development, essential for understanding modern vaccination strategies.