Podcast
Questions and Answers
What is the primary reason for deferring the destruction of live variola virus stocks?
What is the primary reason for deferring the destruction of live variola virus stocks?
What percentage of the smallpox genome can any institution legally possess according to WHO recommendations?
What percentage of the smallpox genome can any institution legally possess according to WHO recommendations?
What is one of the severe complications that can arise from measles infections in children?
What is one of the severe complications that can arise from measles infections in children?
In healthy children, what is the estimated death rate from complications due to measles?
In healthy children, what is the estimated death rate from complications due to measles?
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What is the death rate from measles for immunocompromised individuals?
What is the death rate from measles for immunocompromised individuals?
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Which of the following countries is not currently polio-endemic?
Which of the following countries is not currently polio-endemic?
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What is the main consequence of poliomyelitis infection?
What is the main consequence of poliomyelitis infection?
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Which of the following best describes measles?
Which of the following best describes measles?
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What percentage of the world population has received at least one dose of the COVID-19 vaccine?
What percentage of the world population has received at least one dose of the COVID-19 vaccine?
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What was the significance of Edward Jenner's work in relation to infectious diseases?
What was the significance of Edward Jenner's work in relation to infectious diseases?
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What is the fatality rate of smallpox as mentioned in the content?
What is the fatality rate of smallpox as mentioned in the content?
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How did Jenner test his hypothesis about vaccination?
How did Jenner test his hypothesis about vaccination?
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What ultimately happened to smallpox as a result of vaccination?
What ultimately happened to smallpox as a result of vaccination?
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What was the boundary concern regarding smallpox even after its eradication?
What was the boundary concern regarding smallpox even after its eradication?
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Which of the following accurately reflects the historical context of smallpox vaccination?
Which of the following accurately reflects the historical context of smallpox vaccination?
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What global statistic about COVID-19 vaccinations is highlighted?
What global statistic about COVID-19 vaccinations is highlighted?
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Why are polio vaccines still administered?
Why are polio vaccines still administered?
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What defines herd immunity?
What defines herd immunity?
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Which of the following features impact vaccine effectiveness?
Which of the following features impact vaccine effectiveness?
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What is a reason for using passive immunity?
What is a reason for using passive immunity?
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What characterizes attenuated vaccines?
What characterizes attenuated vaccines?
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How are most flu vaccines produced?
How are most flu vaccines produced?
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What is the main difference between killed and attenuated viruses in vaccines?
What is the main difference between killed and attenuated viruses in vaccines?
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Which of the following best describes the issue with killed viral vaccines?
Which of the following best describes the issue with killed viral vaccines?
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Which Covid-19 vaccine is no longer in use?
Which Covid-19 vaccine is no longer in use?
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What is a key limitation of killed viral vaccines?
What is a key limitation of killed viral vaccines?
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What type of vaccine is primarily used in the flu shot?
What type of vaccine is primarily used in the flu shot?
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Why must the flu vaccine be reformulated each year?
Why must the flu vaccine be reformulated each year?
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Which of the following strains was included in the 2021/22 flu vaccine?
Which of the following strains was included in the 2021/22 flu vaccine?
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What is the general outcome of vaccination in an individual?
What is the general outcome of vaccination in an individual?
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How long did it take to develop the rotavirus vaccine?
How long did it take to develop the rotavirus vaccine?
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What misconception about vaccines has been thoroughly debunked?
What misconception about vaccines has been thoroughly debunked?
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What was the nature of Wakefield's study linking MMR vaccine to autism?
What was the nature of Wakefield's study linking MMR vaccine to autism?
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What happens when vaccination rates drop in the population?
What happens when vaccination rates drop in the population?
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What type of virus is Rotarix?
What type of virus is Rotarix?
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Which vaccine contains a mixture of nonpathogenic cattle rotoviruses?
Which vaccine contains a mixture of nonpathogenic cattle rotoviruses?
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What was the first mRNA vaccine developed against?
What was the first mRNA vaccine developed against?
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What is the primary goal of mRNA vaccines?
What is the primary goal of mRNA vaccines?
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Which of the following vaccines is a protein subunit vaccine?
Which of the following vaccines is a protein subunit vaccine?
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What type of immune cells do mRNA vaccines aim to generate besides neutralizing antibodies?
What type of immune cells do mRNA vaccines aim to generate besides neutralizing antibodies?
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Which of the following statements about mRNA technology is true?
Which of the following statements about mRNA technology is true?
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What common characteristic is shared by vaccines like Measles-mumps-rubella (MMR) and Hepatitis A?
What common characteristic is shared by vaccines like Measles-mumps-rubella (MMR) and Hepatitis A?
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What is a potential outcome of receiving an mRNA vaccine?
What is a potential outcome of receiving an mRNA vaccine?
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What is the significance of booster shots in vaccination?
What is the significance of booster shots in vaccination?
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What is the primary function of adjuvants in vaccines?
What is the primary function of adjuvants in vaccines?
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Which type of immune response do adjuvants primarily activate?
Which type of immune response do adjuvants primarily activate?
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What is a characteristic of coronaviruses?
What is a characteristic of coronaviruses?
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Which of the following coronaviruses was identified in 2003?
Which of the following coronaviruses was identified in 2003?
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Why are vaccines against chronic infections less common?
Why are vaccines against chronic infections less common?
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What role do complement proteins and macrophages play in the immune response?
What role do complement proteins and macrophages play in the immune response?
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What signals indicate that the innate immune response is insufficient?
What signals indicate that the innate immune response is insufficient?
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How do respiratory viruses typically enter host cells?
How do respiratory viruses typically enter host cells?
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Which of the following statements about RNA vaccines is true?
Which of the following statements about RNA vaccines is true?
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What happens to cells infected by viruses?
What happens to cells infected by viruses?
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What primarily limits the size of a cell?
What primarily limits the size of a cell?
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What is a primary goal of synthetic biology?
What is a primary goal of synthetic biology?
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Which principle suggests selecting the hypothesis with the fewest assumptions?
Which principle suggests selecting the hypothesis with the fewest assumptions?
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What is one method used in the scientific method to refine hypotheses?
What is one method used in the scientific method to refine hypotheses?
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What does the limit on cell size affect about cellular function?
What does the limit on cell size affect about cellular function?
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What is the primary structural and functional unit of all living organisms?
What is the primary structural and functional unit of all living organisms?
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Who was the first person to observe microscopic 'animalcules' in pond water?
Who was the first person to observe microscopic 'animalcules' in pond water?
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What term did Robert Hooke use to describe the pores in cork when observed under a microscope?
What term did Robert Hooke use to describe the pores in cork when observed under a microscope?
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Which statement best describes tissues in biological terms?
Which statement best describes tissues in biological terms?
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When were significant advancements in microscopy made that led to the discovery of cells?
When were significant advancements in microscopy made that led to the discovery of cells?
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What does a fully differentiated structural and functional unit in an animal refer to?
What does a fully differentiated structural and functional unit in an animal refer to?
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What is essential for understanding terminology in cell biology?
What is essential for understanding terminology in cell biology?
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What structure is responsible for producing energy in a cell?
What structure is responsible for producing energy in a cell?
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What term is used to refer to the ancient common ancestor of all living cells?
What term is used to refer to the ancient common ancestor of all living cells?
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What do both prokaryotic and eukaryotic cells share?
What do both prokaryotic and eukaryotic cells share?
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Which of the following organisms is commonly used as a model organism in biological research?
Which of the following organisms is commonly used as a model organism in biological research?
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In what unit are cells commonly measured?
In what unit are cells commonly measured?
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What distinguishes eukaryotic cells from prokaryotic cells?
What distinguishes eukaryotic cells from prokaryotic cells?
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What fundamental principle regarding all living organisms is supported by modern biology?
What fundamental principle regarding all living organisms is supported by modern biology?
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What does the phrase 'form reflects function' imply in cellular biology?
What does the phrase 'form reflects function' imply in cellular biology?
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What is a common characteristic of both prokaryotic and eukaryotic cells?
What is a common characteristic of both prokaryotic and eukaryotic cells?
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Which type of cell is generally smaller, prokaryotic or eukaryotic?
Which type of cell is generally smaller, prokaryotic or eukaryotic?
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Which process or structure is common among all cells?
Which process or structure is common among all cells?
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Who were the key figures in articulating the cell theory?
Who were the key figures in articulating the cell theory?
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What is the primary means through which cells reproduce?
What is the primary means through which cells reproduce?
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What do HeLa cells represent in cellular biology?
What do HeLa cells represent in cellular biology?
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Which property of cells allows them to maintain their complexity and ordered state?
Which property of cells allows them to maintain their complexity and ordered state?
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How do cells acquire energy necessary for their functions?
How do cells acquire energy necessary for their functions?
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Which of the following best defines the metabolic activities of a cell?
Which of the following best defines the metabolic activities of a cell?
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What is the main role of motor proteins in cells?
What is the main role of motor proteins in cells?
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What triggers a cell's response to environmental stimuli?
What triggers a cell's response to environmental stimuli?
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What significant concept does the statement 'all cells in an organism contain identical copies of DNA' convey?
What significant concept does the statement 'all cells in an organism contain identical copies of DNA' convey?
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In which process do cells ensure an equal partitioning of genetic material?
In which process do cells ensure an equal partitioning of genetic material?
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What contributes to genetic variation in organisms according to the content?
What contributes to genetic variation in organisms according to the content?
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How do feedback circuits function in cells?
How do feedback circuits function in cells?
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Cells produce energy by converting glucose into which compound?
Cells produce energy by converting glucose into which compound?
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What distinguishes a theory from a hypothesis?
What distinguishes a theory from a hypothesis?
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Which of the following is an example of a scientific law?
Which of the following is an example of a scientific law?
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What is one fundamental difference between prokaryotes and eukaryotes?
What is one fundamental difference between prokaryotes and eukaryotes?
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What limits cell size in living organisms?
What limits cell size in living organisms?
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Which statement best characterizes a hypothesis?
Which statement best characterizes a hypothesis?
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What is the primary role of a cell?
What is the primary role of a cell?
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Who was responsible for the invention of the microscope that led to the discovery of cells?
Who was responsible for the invention of the microscope that led to the discovery of cells?
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What term did Hooke use to describe the structures he observed in cork?
What term did Hooke use to describe the structures he observed in cork?
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What is an organ defined as in the context of cell biology?
What is an organ defined as in the context of cell biology?
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What did Anton Leewenhoek contribute to the field of cell biology?
What did Anton Leewenhoek contribute to the field of cell biology?
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How should students utilize the glossary provided in their resources?
How should students utilize the glossary provided in their resources?
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What defines tissues in the context of cellular organization?
What defines tissues in the context of cellular organization?
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What was Hooke's observation regarding cork cells influenced by?
What was Hooke's observation regarding cork cells influenced by?
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What limits the size of a cell?
What limits the size of a cell?
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What is the purpose of synthetic biology?
What is the purpose of synthetic biology?
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Which of the following describes Occam's razor?
Which of the following describes Occam's razor?
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How are scientific theories assessed according to the scientific method?
How are scientific theories assessed according to the scientific method?
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What distinguishes a theory from a hypothesis in scientific terms?
What distinguishes a theory from a hypothesis in scientific terms?
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What is one of the factors that can increase cell size beyond normal limits?
What is one of the factors that can increase cell size beyond normal limits?
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Which of the following best characterizes a scientific law?
Which of the following best characterizes a scientific law?
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What are the fundamental differences between prokaryotes and eukaryotes?
What are the fundamental differences between prokaryotes and eukaryotes?
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What limits cell size in biological entities?
What limits cell size in biological entities?
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Which of the following statements is the best definition of a hypothesis?
Which of the following statements is the best definition of a hypothesis?
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Which statement accurately reflects a characteristic shared by prokaryotic and eukaryotic cells?
Which statement accurately reflects a characteristic shared by prokaryotic and eukaryotic cells?
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What is the significance of LUCA in the study of cellular evolution?
What is the significance of LUCA in the study of cellular evolution?
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Which type of cells are generally smaller and simpler in structure?
Which type of cells are generally smaller and simpler in structure?
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Which of the following organisms is NOT classified as a eukaryotic model organism?
Which of the following organisms is NOT classified as a eukaryotic model organism?
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What do cells share that indicates their common ancestry?
What do cells share that indicates their common ancestry?
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What does the concept 'form reflects function' imply in cellular biology?
What does the concept 'form reflects function' imply in cellular biology?
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How can cells be measured commonly?
How can cells be measured commonly?
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What distinguishes prokaryotic cells from eukaryotic cells?
What distinguishes prokaryotic cells from eukaryotic cells?
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Which of the following features do all cells share?
Which of the following features do all cells share?
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Which factor contributes to the classification of organisms as model organisms in biological studies?
Which factor contributes to the classification of organisms as model organisms in biological studies?
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Who articulated the cell theory in the mid-1800s?
Who articulated the cell theory in the mid-1800s?
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What property allows cells to reproduce?
What property allows cells to reproduce?
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What is the sum total of chemical reactions taking place in a cell known as?
What is the sum total of chemical reactions taking place in a cell known as?
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Which process do cells utilize to acquire energy from glucose?
Which process do cells utilize to acquire energy from glucose?
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Which of the following statements is true about genetic information in cells?
Which of the following statements is true about genetic information in cells?
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What characteristic allows cells to adapt to their environments and respond to stimuli?
What characteristic allows cells to adapt to their environments and respond to stimuli?
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What role do motor proteins play in cells?
What role do motor proteins play in cells?
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What is one essential function of enzymes in cellular processes?
What is one essential function of enzymes in cellular processes?
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Why are HeLa cells significant in biological research?
Why are HeLa cells significant in biological research?
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How do most cells respond to environmental stimuli?
How do most cells respond to environmental stimuli?
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Which of the following best describes the cellular process of division?
Which of the following best describes the cellular process of division?
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Which of the following best describes the complexity of cells?
Which of the following best describes the complexity of cells?
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What defines a self-regulating cell?
What defines a self-regulating cell?
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How do cells acquire energy for functioning?
How do cells acquire energy for functioning?
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What structure is considered the basic microscopic unit of all living beings?
What structure is considered the basic microscopic unit of all living beings?
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What did Robert Hooke discover when he first used the microscope?
What did Robert Hooke discover when he first used the microscope?
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Which scientist is credited with the refinement of the microscope in the 17th century?
Which scientist is credited with the refinement of the microscope in the 17th century?
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What term describes a group of cells that aggregate to perform a specific function?
What term describes a group of cells that aggregate to perform a specific function?
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What is the significance of Hooke's observations in relation to the study of cell biology?
What is the significance of Hooke's observations in relation to the study of cell biology?
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In the early study of microscopy, what did Hooke refer to the small units he observed?
In the early study of microscopy, what did Hooke refer to the small units he observed?
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What type of organisms did Leewenhoek observe under the microscope?
What type of organisms did Leewenhoek observe under the microscope?
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What resource is recommended for understanding the terminology used in cell biology?
What resource is recommended for understanding the terminology used in cell biology?
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What distinguishes a scientific law from a hypothesis?
What distinguishes a scientific law from a hypothesis?
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Which of the following statements is true about theories in science?
Which of the following statements is true about theories in science?
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What characteristic allows a hypothesis to be scientifically useful?
What characteristic allows a hypothesis to be scientifically useful?
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What is one of the fundamental differences between prokaryotes and eukaryotes?
What is one of the fundamental differences between prokaryotes and eukaryotes?
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What is the term used for the ancient cell from which all living organisms evolved?
What is the term used for the ancient cell from which all living organisms evolved?
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Which statement accurately distinguishes prokaryotic cells from eukaryotic cells?
Which statement accurately distinguishes prokaryotic cells from eukaryotic cells?
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Which feature is shared by both prokaryotic and eukaryotic cells?
Which feature is shared by both prokaryotic and eukaryotic cells?
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What is a fundamental principle regarding the relationship between cellular form and function?
What is a fundamental principle regarding the relationship between cellular form and function?
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Which of the following is NOT a type of eukaryotic model organism mentioned?
Which of the following is NOT a type of eukaryotic model organism mentioned?
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What unit is commonly used to measure cell sizes?
What unit is commonly used to measure cell sizes?
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What characteristic is primarily associated with eukaryotic cells compared to prokaryotic cells?
What characteristic is primarily associated with eukaryotic cells compared to prokaryotic cells?
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What role do ribosomes play in cells?
What role do ribosomes play in cells?
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Which of the following statements best describes the metabolic pathways in prokaryotic and eukaryotic cells?
Which of the following statements best describes the metabolic pathways in prokaryotic and eukaryotic cells?
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Which of the following is a principle associated with the scientific method?
Which of the following is a principle associated with the scientific method?
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What is the main goal of synthetic biology?
What is the main goal of synthetic biology?
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Which factor limits the volume of cytoplasm in a cell?
Which factor limits the volume of cytoplasm in a cell?
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What does the term 'tenuous' imply in the context of scientific facts?
What does the term 'tenuous' imply in the context of scientific facts?
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Which statement accurately reflects a property of cells?
Which statement accurately reflects a property of cells?
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What is a primary method through which cells reproduce?
What is a primary method through which cells reproduce?
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Which structure is crucial for energy conversion in animal cells?
Which structure is crucial for energy conversion in animal cells?
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What is the term for the sum total of all chemical reactions in a cell?
What is the term for the sum total of all chemical reactions in a cell?
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How do cells typically respond to external stimuli?
How do cells typically respond to external stimuli?
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What distinguishes HeLa cells in cell biology?
What distinguishes HeLa cells in cell biology?
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What is one function of motor proteins in cells?
What is one function of motor proteins in cells?
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What is a critical emerging property of cells discussed in the materials?
What is a critical emerging property of cells discussed in the materials?
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Which property of cells allows them to be highly organized?
Which property of cells allows them to be highly organized?
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How does photosynthesis contribute to cellular processes in animals?
How does photosynthesis contribute to cellular processes in animals?
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What is the role of Enzymes in cellular chemical reactions?
What is the role of Enzymes in cellular chemical reactions?
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Which statement is NOT true about the genetic information in cells?
Which statement is NOT true about the genetic information in cells?
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What type of energy process depends on chloroplasts in certain cells?
What type of energy process depends on chloroplasts in certain cells?
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Flashcards
Vaccination
Vaccination
A process that uses a vaccine to build immunity to a disease.
Smallpox
Smallpox
An infectious disease that was once very common and deadly but has been eradicated.
Edward Jenner
Edward Jenner
A doctor who pioneered the concept of vaccination against smallpox.
Cowpox
Cowpox
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Vaccine effectiveness
Vaccine effectiveness
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Smallpox eradication
Smallpox eradication
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Global vaccination efforts
Global vaccination efforts
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Vaccine samples
Vaccine samples
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Smallpox containment risk
Smallpox containment risk
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Variola virus research
Variola virus research
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Smallpox genome control
Smallpox genome control
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Measles infection
Measles infection
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Measles vaccination
Measles vaccination
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Polio infection
Polio infection
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Polio endemic countries
Polio endemic countries
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Polio vaccination effectiveness
Polio vaccination effectiveness
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Herd Immunity
Herd Immunity
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Why do we still need Polio vaccines?
Why do we still need Polio vaccines?
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What is the leading cause of death globally?
What is the leading cause of death globally?
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Features of Pathogens That Affect Vaccine Effectiveness
Features of Pathogens That Affect Vaccine Effectiveness
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What makes measles vaccine unique?
What makes measles vaccine unique?
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When is passive immunity used?
When is passive immunity used?
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Types of COVID-19 Vaccines
Types of COVID-19 Vaccines
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Live Attenuated Vaccines
Live Attenuated Vaccines
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How are most viral vaccines made?
How are most viral vaccines made?
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What is an attenuated virus?
What is an attenuated virus?
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SARS-CoV-2 Replication in Eggs
SARS-CoV-2 Replication in Eggs
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Current Flu Shot Composition
Current Flu Shot Composition
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Why the Flu Shot Changes Each Year?
Why the Flu Shot Changes Each Year?
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What Does the Flu Shot Do?
What Does the Flu Shot Do?
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Rotavirus Vaccine Development Time
Rotavirus Vaccine Development Time
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Rotavirus - A Serious Threat
Rotavirus - A Serious Threat
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Two Rotavirus Vaccines
Two Rotavirus Vaccines
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H1N1 Pandemic Vaccine Development
H1N1 Pandemic Vaccine Development
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Vaccinations and Measles Incidence
Vaccinations and Measles Incidence
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Autism and Vaccination - Misconception
Autism and Vaccination - Misconception
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mRNA Vaccines: Goal
mRNA Vaccines: Goal
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mRNA Vaccine Delivery
mRNA Vaccine Delivery
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First mRNA Vaccine
First mRNA Vaccine
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Commercial Potential of mRNA Vaccines
Commercial Potential of mRNA Vaccines
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RNA Vaccine: How it Works?
RNA Vaccine: How it Works?
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Protein Subunit Vaccine: How it Works?
Protein Subunit Vaccine: How it Works?
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Pfizer-BioNTech and Moderna Vaccines
Pfizer-BioNTech and Moderna Vaccines
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Booster Shots
Booster Shots
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Adjuvants in Vaccines
Adjuvants in Vaccines
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How do Adjuvants Work?
How do Adjuvants Work?
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What is a Virus?
What is a Virus?
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Viral Proteins
Viral Proteins
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Coronaviruses: Zoonotic
Coronaviruses: Zoonotic
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What are RNA Vaccines?
What are RNA Vaccines?
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How do RNA Vaccines Work?
How do RNA Vaccines Work?
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First Line of Defense Against Viruses
First Line of Defense Against Viruses
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When Does the Adaptive Immune System Kick In?
When Does the Adaptive Immune System Kick In?
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How Do Respiratory Viruses Enter Cells?
How Do Respiratory Viruses Enter Cells?
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Cell Size Limit
Cell Size Limit
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Acetabularia
Acetabularia
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Synthetic Biology
Synthetic Biology
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Scientific Method
Scientific Method
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Occam's Razor
Occam's Razor
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Cell
Cell
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Tissue
Tissue
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Organ
Organ
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What is the role of Microscopy in discovering cells?
What is the role of Microscopy in discovering cells?
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Hooke's Observation of Cells
Hooke's Observation of Cells
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Leeuwenhoek's Discovery
Leeuwenhoek's Discovery
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What are the fundamental units of all living organisms?
What are the fundamental units of all living organisms?
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What are the on-line resources available for Cell Biology study?
What are the on-line resources available for Cell Biology study?
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LUCA
LUCA
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Prokaryotic Cells
Prokaryotic Cells
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Eukaryotic Cells
Eukaryotic Cells
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Common Features of All Cells
Common Features of All Cells
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Model Organisms in Biology
Model Organisms in Biology
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Micrometer (μm)
Micrometer (μm)
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Nanometer (nm)
Nanometer (nm)
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Form Reflects Function
Form Reflects Function
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Cellular Biochemistry
Cellular Biochemistry
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Cell Biology
Cell Biology
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Hypothesis
Hypothesis
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Theory
Theory
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What are the 3 tenants of cell theory?
What are the 3 tenants of cell theory?
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What limits cell size?
What limits cell size?
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Cell Theory
Cell Theory
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HeLa Cells
HeLa Cells
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Cultured Cells
Cultured Cells
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What Makes Cells Complex?
What Makes Cells Complex?
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Evolutionary Conservation
Evolutionary Conservation
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Genes & Cellular Activity
Genes & Cellular Activity
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Mutations and Evolution
Mutations and Evolution
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How Cells Reproduce
How Cells Reproduce
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Photosynthesis & Energy
Photosynthesis & Energy
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Cellular Respiration
Cellular Respiration
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Enzymes & Metabolism
Enzymes & Metabolism
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Mechanical Activities in Cells
Mechanical Activities in Cells
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Cells & Stimuli
Cells & Stimuli
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Self-Regulation in Cells
Self-Regulation in Cells
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Cells & Evolution
Cells & Evolution
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Microscope
Microscope
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Robert Hooke
Robert Hooke
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Anton Leewenhoek
Anton Leewenhoek
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What are the three tenets of cell theory?
What are the three tenets of cell theory?
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What are model organisms?
What are model organisms?
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Matthias Schleiden
Matthias Schleiden
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Theodor Schwann
Theodor Schwann
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Rudolf Virchow
Rudolf Virchow
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What are the three main components of cell theory?
What are the three main components of cell theory?
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What are the basic properties of cells?
What are the basic properties of cells?
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Photosynthesis: Energy Source
Photosynthesis: Energy Source
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Cellular Respiration: Energy Conversion
Cellular Respiration: Energy Conversion
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Enzymes & Metabolism: Chemical Reactions
Enzymes & Metabolism: Chemical Reactions
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Model Organisms
Model Organisms
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What is Synthetic Biology?
What is Synthetic Biology?
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The Scientific Method
The Scientific Method
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What are the basic units of life?
What are the basic units of life?
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What is the role of microscopy in cell biology?
What is the role of microscopy in cell biology?
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What did Robert Hooke observe?
What did Robert Hooke observe?
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What did Anton Leewenhoek discover?
What did Anton Leewenhoek discover?
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Cell size limitation
Cell size limitation
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What is the scientific method?
What is the scientific method?
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Who articulated the Cell Theory?
Who articulated the Cell Theory?
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Cell Division
Cell Division
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What is a Gene?
What is a Gene?
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What is Metabolism?
What is Metabolism?
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What is Photosynthesis?
What is Photosynthesis?
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What is Cellular Respiration?
What is Cellular Respiration?
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What are Enzymes?
What are Enzymes?
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What are Motor Proteins?
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What is Self-Regulation in Cells?
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What is Evolutionary Conservation?
What is Evolutionary Conservation?
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What is LUCA?
What is LUCA?
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Prokaryotes vs. Eukaryotes
Prokaryotes vs. Eukaryotes
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What are HeLa Cells?
What are HeLa Cells?
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What are Cultured Cells?
What are Cultured Cells?
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Study Notes
Vaccination
- Cartoon depicts anti-vaccine sentiments and misinformation
- Cartoon highlights the spread of misinformation regarding vaccines and encourages community vaccination
Global Vaccine Situation
- 775,251,779 total COVID-19 cases reported as of March 31, 2024
- 7,043,660 total COVID-19 deaths reported as of March 31, 2024
- 13.57 billion doses of COVID-19 vaccines administered globally
- 70.6% of the world's population has received at least one dose of a COVID-19 vaccine
- 32.7% of low-income countries have received at least one dose of a COVID-19 vaccine
Smallpox Vaccination
- Smallpox was a deadly disease with a 20-60% fatality rate
- Survivors were often immune after contracting the disease
- Observations linked milkmaids contracting cowpox to immunity against smallpox
- In May 1796, Jenner used material from a cowpox lesion to inoculate an 8-year-old boy, who did not contract smallpox later
- Jenner's work was a first attempt to control an infectious disease
Smallpox Eradication and Current Status
- Smallpox was officially eradicated after a three-year period (no cases)
- Smallpox vaccines are no longer administered
- Frozen smallpox samples exist in the US and Russia; controversy regarding their destruction
- A gas explosion at a Russian lab in 2019 involved smallpox samples, but no samples were compromised
- WHO recommended deferring live variola virus stock destruction by up to five years
Measles Vaccination
- Measles is a highly contagious viral disease leading to pneumonia, encephalitis and pregnancy complications
- Measles is one of the leading vaccine-preventable causes of death globally
- Healthy children have a 1 in 1000 risk of contracting encephalitis after measles, often resulting in permanent brain damage
- Healthy children have a 1-2 in 1000 risk of death after measles from respiratory or neurological complications
- Immunocompromised individuals have a near 30% risk of death from measles.
- Measles is still a global concern.
Polio Vaccination
- Poliomyelitis is a viral infection that can cause nerve damage and paralysis
- Currently, there are only three countries with ongoing polio epidemics: Pakistan, Afghanistan, and Nigeria
- Polio vaccines are still administered globally to prevent epidemic outbreaks due to high international travel volume
Herd Immunity
- Herd immunity occurs when most of a population is immune to an infectious disease
- The spread of disease in a community with herd immunity is reduced
- This helps protect susceptible individuals
Infectious Diseases
- Infectious diseases remain the leading cause of death globally
- This section lists several infectious diseases and the effective vaccines for each
Effective Vaccines
- Effective vaccines must not cause illness themselves and offer sustained protection against disease
- Effective vaccines must elicit enduring immunity to pathogens
- Safe vaccines for use in humans must either be inactive (killed) or attenuated (weakened) forms of virus
Flu Vaccine
- Most flu vaccines are grown in fertilized chicken eggs (~82%)
- Cell-based flu vaccines are emerging as an alternative
- Flu vaccines must be reformulated annually due to viral variations
COVID-19 Vaccines
- Three different types of COVID-19 vaccines are currently used: mRNA, protein subunit, and adenoviral vector vaccines
- COVID-19 vaccines involve mRNA technology and contain the instructions to produce the COVID-19 spike protein, which generate an immune response in humans
Immune System Response to Viral Attack
- Initial defense against viral attack are complement proteins and macrophages
- Natural killer cells and additional phagocytes (neutrophils) are activated if response is insufficient
- Adaptive immune system is slower to respond to new viruses if innate immune system is overwhelmed.
Viral Replication and Vaccination
- Most viral vaccines are made from killed or attenuated viruses to elicit an immune response
- Killed viruses are not capable of replicating
- Attenuated viruses are capable of replicating but lack pathogenicity in humans
Additional Information
- Adjuvants are substances added to vaccines to strengthen the immune response
- A variety of vaccines are used for different purposes.
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Description
Explore the evolution of vaccination with a focus on smallpox and COVID-19. This quiz examines the spread of misinformation and highlights the crucial role of vaccines in global health. Test your knowledge on key statistical data and historical milestones in vaccination.