β Adrenergic Blockers in Ophthalmology
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Questions and Answers

Which of the following is NOT affected by topical β blockers?

  • Intraocular pressure (i.o.t.)
  • Pupil size (correct)
  • Tone of ciliary muscle
  • Outflow facility

Why are ocular β blockers designed to be lipophilic?

  • To increase aqueous formation
  • To avoid corneal hypoesthesia
  • To reduce systemic effects (correct)
  • To increase systemic effects

What is the likely mechanism behind the reduction in ocular blood flow by β blockers?

  • Blockade of β2 receptors in the ciliary epithelium (correct)
  • Activation of adenylylcyclase
  • Upregulation of β2 receptors
  • Increased aqueous formation

What is a common systemic adverse effect associated with ocular β blockers?

<p>Bronchospasm in asthmatic patients (B)</p> Signup and view all the answers

How can systemic adverse effects of ocular β blockers be minimized?

<p>Applying pressure on the inner canthus of the eye (B)</p> Signup and view all the answers

What ocular side effect is generally mild and infrequent with β blockers?

<p>Corneal hypoesthesia (D)</p> Signup and view all the answers

What is the primary mechanism by which β blockers lower intraocular pressure (i.o.t.)?

<p>Reducing aqueous formation (D)</p> Signup and view all the answers

Why are ocular β blockers preferred over miotics in current practice?

<p>They cause less ocular side effects (C)</p> Signup and view all the answers

What is a distinguishing characteristic of ocular β blockers that helps reduce systemic effects?

<p>High ocular capture (D)</p> Signup and view all the answers

Which of the following systemic adverse effects is commonly associated with ocular β blockers?

<p>Bradycardia (C)</p> Signup and view all the answers

How do systemic adverse effects occur in patients using ocular β blockers?

<p>Absorption through the nasolacrimal duct (D)</p> Signup and view all the answers

Which population is at higher risk for experiencing life-threatening bronchospasm when using ocular β blockers?

<p>Elderly individuals (A)</p> Signup and view all the answers

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