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12 Questions

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β Adrenergic Blockers in Ophthalmology

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Questions and Answers

Which of the following is NOT affected by topical β blockers?

Intraocular pressure (i.o.t.)

Pupil size (correct)

Tone of ciliary muscle

Outflow facility

Why are ocular β blockers designed to be lipophilic?

To increase aqueous formation

To avoid corneal hypoesthesia

To reduce systemic effects (correct)

To increase systemic effects

What is the likely mechanism behind the reduction in ocular blood flow by β blockers?

Blockade of β2 receptors in the ciliary epithelium (correct)

Activation of adenylylcyclase

Upregulation of β2 receptors

Increased aqueous formation

What is a common systemic adverse effect associated with ocular β blockers?

Bronchospasm in asthmatic patients Signup and view all the answers

How can systemic adverse effects of ocular β blockers be minimized?

Applying pressure on the inner canthus of the eye Signup and view all the answers

What ocular side effect is generally mild and infrequent with β blockers?

Corneal hypoesthesia Signup and view all the answers

What is the primary mechanism by which β blockers lower intraocular pressure (i.o.t.)?

Reducing aqueous formation Signup and view all the answers

Why are ocular β blockers preferred over miotics in current practice?

They cause less ocular side effects Signup and view all the answers

What is a distinguishing characteristic of ocular β blockers that helps reduce systemic effects?

High ocular capture Signup and view all the answers

Which of the following systemic adverse effects is commonly associated with ocular β blockers?

Bradycardia Signup and view all the answers

How do systemic adverse effects occur in patients using ocular β blockers?

Absorption through the nasolacrimal duct Signup and view all the answers

Which population is at higher risk for experiencing life-threatening bronchospasm when using ocular β blockers?

Elderly individuals Signup and view all the answers