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USP General Chapter: Handling Hazardous Drugs
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USP General Chapter: Handling Hazardous Drugs

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Questions and Answers

What is the primary purpose of USP General Chapter <800>?

  • To describe standards for handling hazardous drugs to ensure safety of patient, worker, and environment (correct)
  • To describe standards for handling non-hazardous drugs
  • To describe standards for handling radiopharmaceuticals
  • To describe standards for handling sterile compounding

    • What type of drugs require further manipulation and must follow USP <800> guidelines?

  • Drugs that are not hazardous
  • Final dosage forms such as tablets and capsules
  • Drugs that do not require containment
  • Any hazardous drug API, antineoplastic requiring manipulation (correct)

    • What is the purpose of performing a risk assessment according to USP <800>?

  • To determine the dosage form of a drug
  • To determine the risk of exposure when full USP requirements are not met (correct)
  • To identify non-hazardous drugs
  • To identify all hazardous drugs

    • What is the primary engineering control required for sterile compounding of hazardous drugs?

    <p>C-PEC ventilated device</p> Signup and view all the answers

    What type of personal protective equipment (PPE) is required for sterile compounding of hazardous drugs?

    <p>Gloves, gowns, head/hair covering, facial hair covering, shoe covers, and eye face protection</p> Signup and view all the answers

    When should personal protective equipment (PPE) be worn when handling hazardous drugs?

    <p>During receipt, storage, transport, compounding, administration, deactivation/decontamination/cleaning/disinfecting, spill control, and waste disposal</p> Signup and view all the answers

    What is the purpose of deactivation in the handling of hazardous drugs?

    <p>To render the compound inert or inactive</p> Signup and view all the answers

    What is the correct sequence of cleaning steps for hazardous drug compounding?

    <p>Deactivated, decontaminated, cleaned</p> Signup and view all the answers

    What is the purpose of disinfection in the handling of hazardous drugs?

    <p>To destroy microorganisms</p> Signup and view all the answers

    Hazardous drugs that require manipulation include only antineoplastic drugs.

    <p>False</p> Signup and view all the answers

    The primary engineering control for sterile compounding of hazardous drugs is a glove.

    <p>False</p> Signup and view all the answers

    A risk assessment is only performed when handling antineoplastic drugs.

    <p>False</p> Signup and view all the answers

    The NIOSH criteria for a hazardous drug include only carcinogenicity and teratogenicity.

    <p>False</p> Signup and view all the answers

    Decontamination involves removing organic and inorganic material.

    <p>False</p> Signup and view all the answers

    Personal protective equipment (PPE) is only required for compounding and administration of hazardous drugs.

    <p>False</p> Signup and view all the answers

    All hazardous drugs require the same level of containment regardless of dosage form.

    <p>False</p> Signup and view all the answers

    A hazardous drug can be classified into only one of the three groups according to NIOSH criteria.

    <p>False</p> Signup and view all the answers

    Disinfection involves removing HD residue from surfaces.

    <p>False</p> Signup and view all the answers

    The sequence of cleaning steps for hazardous drug compounding is deactivation, decontamination, cleaning, and disinfection.

    <p>True</p> Signup and view all the answers

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