USP General Chapter: Handling Hazardous Drugs
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Questions and Answers

What is the primary purpose of USP General Chapter <800>?

  • To describe standards for handling hazardous drugs to ensure safety of patient, worker, and environment (correct)
  • To describe standards for handling non-hazardous drugs
  • To describe standards for handling radiopharmaceuticals
  • To describe standards for handling sterile compounding

What type of drugs require further manipulation and must follow USP <800> guidelines?

  • Drugs that are not hazardous
  • Final dosage forms such as tablets and capsules
  • Drugs that do not require containment
  • Any hazardous drug API, antineoplastic requiring manipulation (correct)

What is the purpose of performing a risk assessment according to USP <800>?

  • To determine the dosage form of a drug
  • To determine the risk of exposure when full USP requirements are not met (correct)
  • To identify non-hazardous drugs
  • To identify all hazardous drugs

What is the primary engineering control required for sterile compounding of hazardous drugs?

<p>C-PEC ventilated device (C)</p> Signup and view all the answers

What type of personal protective equipment (PPE) is required for sterile compounding of hazardous drugs?

<p>Gloves, gowns, head/hair covering, facial hair covering, shoe covers, and eye face protection (B)</p> Signup and view all the answers

When should personal protective equipment (PPE) be worn when handling hazardous drugs?

<p>During receipt, storage, transport, compounding, administration, deactivation/decontamination/cleaning/disinfecting, spill control, and waste disposal (B)</p> Signup and view all the answers

What is the purpose of deactivation in the handling of hazardous drugs?

<p>To render the compound inert or inactive (D)</p> Signup and view all the answers

What is the correct sequence of cleaning steps for hazardous drug compounding?

<p>Deactivated, decontaminated, cleaned (C)</p> Signup and view all the answers

What is the purpose of disinfection in the handling of hazardous drugs?

<p>To destroy microorganisms (A)</p> Signup and view all the answers

Hazardous drugs that require manipulation include only antineoplastic drugs.

<p>False (B)</p> Signup and view all the answers

The primary engineering control for sterile compounding of hazardous drugs is a glove.

<p>False (B)</p> Signup and view all the answers

A risk assessment is only performed when handling antineoplastic drugs.

<p>False (B)</p> Signup and view all the answers

The NIOSH criteria for a hazardous drug include only carcinogenicity and teratogenicity.

<p>False (B)</p> Signup and view all the answers

Decontamination involves removing organic and inorganic material.

<p>False (B)</p> Signup and view all the answers

Personal protective equipment (PPE) is only required for compounding and administration of hazardous drugs.

<p>False (B)</p> Signup and view all the answers

All hazardous drugs require the same level of containment regardless of dosage form.

<p>False (B)</p> Signup and view all the answers

A hazardous drug can be classified into only one of the three groups according to NIOSH criteria.

<p>False (B)</p> Signup and view all the answers

Disinfection involves removing HD residue from surfaces.

<p>False (B)</p> Signup and view all the answers

The sequence of cleaning steps for hazardous drug compounding is deactivation, decontamination, cleaning, and disinfection.

<p>True (A)</p> Signup and view all the answers

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