Urinary System Overview
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Questions and Answers

Which structure within the kidney is responsible for collecting urine from a single kidney lobe?

  • Minor calyx (correct)
  • Renal lobe
  • Major calyx
  • Renal pelvis

What is the approximate amount of cardiac output delivered to the kidneys by the renal arteries each minute?

  • 1200 ml (correct)
  • 800 ml
  • 1500 ml
  • 600 ml

Which of the following correctly describes the flow of blood through the arterial supply to the kidneys?

  • Renal → Interlobar → Arcuate → Cortical radiate
  • Cortical radiate → Arcuate → Interlobar → Segmental → Renal
  • Segmental → Renal → Interlobar → Cortical radiate → Arcuate
  • Renal → Segmental → Interlobar → Arcuate → Cortical radiate (correct)

Which component of the urinary system is described as a funnel-shaped structure that collects urine from major calyces?

<p>Renal pelvis (C)</p> Signup and view all the answers

How many lobes does each kidney approximately contain?

<p>6 (C)</p> Signup and view all the answers

Which structure separates adjacent renal pyramids within the kidney?

<p>Renal column (C)</p> Signup and view all the answers

What unique characteristic is true regarding the venous flow in the kidney?

<p>Segmental veins are present (C)</p> Signup and view all the answers

What is the tip of the renal pyramid called?

<p>Renal papilla (A)</p> Signup and view all the answers

Which segment of the nephron is primarily responsible for reabsorbing water and sodium ions?

<p>Collecting duct (A)</p> Signup and view all the answers

What role do intercalated cells in the nephron play in kidney function?

<p>Reabsorbing hydrogen and bicarbonate ions (A)</p> Signup and view all the answers

Which structure collects fluid from multiple collecting ducts in the nephron?

<p>Papillary duct (C)</p> Signup and view all the answers

What is the main function of the proximal convoluted tubule in the nephron?

<p>Reabsorption of water, ions, and nutrients (A)</p> Signup and view all the answers

Which of the following best describes the flow of tubular fluid in the nephron?

<p>It varies by segment, influenced by hormonal regulation. (C)</p> Signup and view all the answers

Which layer of supportive tissue is closest to the kidney itself?

<p>Fibrous capsule (B)</p> Signup and view all the answers

What anatomical feature of the kidney is responsible for the entry and exit of renal blood vessels and nerves?

<p>Renal hilum (B)</p> Signup and view all the answers

The right kidney is positioned lower than the left due to which anatomical consideration?

<p>Liver crowding the kidney (C)</p> Signup and view all the answers

The kidneys are primarily located in which anatomical space?

<p>Retroperitoneal space (C)</p> Signup and view all the answers

Which of the following structures is NOT associated with the renal hilum?

<p>Renal cortex (B)</p> Signup and view all the answers

What is the primary function of the kidneys in relation to drugs and toxins?

<p>Eliminate drugs and toxins (C)</p> Signup and view all the answers

What is the average length of the kidney?

<p>4 inches (B)</p> Signup and view all the answers

What role do the ureters play in relation to the urinary bladder?

<p>They connect the kidneys to the bladder (A)</p> Signup and view all the answers

Which component is NOT considered part of the renal structure?

<p>Urethra (B)</p> Signup and view all the answers

Which part of the kidney appears convex when viewed from the lateral surface?

<p>Lateral surface (B)</p> Signup and view all the answers

What is the primary function of the glomerulus in the renal corpuscle?

<p>Filtration of blood to form filtrate (D)</p> Signup and view all the answers

Which layer of the glomerular capsule consists of simple squamous epithelium?

<p>Parietal layer (A)</p> Signup and view all the answers

What is the nature of the filtrate produced by the renal corpuscle?

<p>Protein-free and similar to blood plasma (C)</p> Signup and view all the answers

What type of capillaries compose the glomerulus, allowing for efficient filtration?

<p>Fenestrated capillaries with a porous endothelium (A)</p> Signup and view all the answers

Which component of the renal tubule is involved in modifying the filtrate to create urine?

<p>Tubular passageway (B)</p> Signup and view all the answers

What role do podocytes play in the glomerular structure?

<p>They cling to the glomerular capillaries and form filtration slits. (A)</p> Signup and view all the answers

What is the maximum length of the renal tubule?

<p>Up to 50 mm (D)</p> Signup and view all the answers

The two layers of the glomerular capsule include which of the following?

<p>Parietal and visceral layers (D)</p> Signup and view all the answers

How is blood pressure related to the filtration process in the renal corpuscle?

<p>It forces water and solutes out of the capillaries. (B)</p> Signup and view all the answers

Which of the following accurately describes the renal plexus?

<p>A network of autonomic nerve fibers that regulates renal blood flow (A)</p> Signup and view all the answers

What is the primary function of cortical nephrons?

<p>Performing most regulatory functions of the kidney (A)</p> Signup and view all the answers

Which type of nephron is primarily responsible for producing concentrated urine?

<p>Juxtamedullary nephron (B)</p> Signup and view all the answers

How many approximate nephrons are found in a single kidney?

<p>Approximately 1 million (A)</p> Signup and view all the answers

What is the main role of the juxtamedullary nephrons?

<p>Contributing to urine concentration (B)</p> Signup and view all the answers

Which structure serves as a conical mass within the renal medulla?

<p>Renal papilla (C)</p> Signup and view all the answers

Which statement correctly distinguishes between major and minor calyces?

<p>Minor calyces drain urine into major calyces that then lead to the renal pelvis (D)</p> Signup and view all the answers

What regulates the release of renin in the kidneys?

<p>Sympathetic nerve fibers of the renal plexus (D)</p> Signup and view all the answers

What is a primary characteristic of juxtamedullary nephrons?

<p>Long nephron loops that extend deep into the medulla (B)</p> Signup and view all the answers

Which muscle fiber type is characterized by the highest capacity for generating ATP?

<p>Slow Oxidative (SO) Fibers (D)</p> Signup and view all the answers

What is the primary method of ATP production for Fast Glycolytic (FG) Fibers?

<p>Anaerobic glycolysis (B)</p> Signup and view all the answers

Which characteristic differentiates Slow Oxidative (SO) Fibers from Fast Glycolytic (FG) Fibers?

<p>Higher myoglobin content (D)</p> Signup and view all the answers

What is the primary color associated with Fast Glycolytic (FG) Fibers due to their low myoglobin content?

<p>White (pale) (B)</p> Signup and view all the answers

Which muscle fiber type exhibits the fastest contraction velocity?

<p>Fast Glycolytic (FG) Fibers (D)</p> Signup and view all the answers

Which muscle fiber type is characterized by many mitochondria?

<p>Slow Oxidative (SO) Fibers (A)</p> Signup and view all the answers

What is the level of glycogen stores in Fast Glycolytic (FG) Fibers compared to Slow Oxidative (SO) Fibers?

<p>Lower in Slow Oxidative (SO) Fibers (B)</p> Signup and view all the answers

What distinguishes juxtamedullary nephrons from cortical nephrons?

<p>Juxtamedullary nephrons have long nephron loops that extend deep into the medulla. (D)</p> Signup and view all the answers

Which function is primarily regulated by the renal plexus?

<p>Regulation of renal blood flow. (D)</p> Signup and view all the answers

What percentage of nephrons in the kidney are cortical nephrons?

<p>85 percent (D)</p> Signup and view all the answers

What is the primary role of the renin released from the kidneys?

<p>To regulate blood pressure. (D)</p> Signup and view all the answers

Which structure is part of the renal blood supply network and contributes to autonomic regulation?

<p>Renal plexus (A)</p> Signup and view all the answers

What structure anchors the kidney to surrounding organs and tissues?

<p>Renal fascia (C)</p> Signup and view all the answers

Which component provides a thick layer of adipose tissue surrounding the kidney?

<p>Perirenal fat (B)</p> Signup and view all the answers

Which of the following factors does NOT maintain the position of the kidneys?

<p>Kidney size (A)</p> Signup and view all the answers

What happens to Martine's abdominal pain when she shifts from a supine to a prone position?

<p>It decreases. (B)</p> Signup and view all the answers

What is the most definitive test for diagnosing nephroptosis?

<p>Imaging diagnosis (B)</p> Signup and view all the answers

Which symptom is exacerbated by the moderate consumption of alcohol, according to Martine's complaints?

<p>Frequent micturition (C)</p> Signup and view all the answers

The fibrous capsule covering the outer surface of the kidney is made of which type of tissue?

<p>Collagen fibers (B)</p> Signup and view all the answers

Which symptom is most indicative of nephroptosis?

<p>Abdominal pain that improves when lying supine (C)</p> Signup and view all the answers

What type of physical examination finding was noted in Martine?

<p>Thin physique (B)</p> Signup and view all the answers

What structural change would occur if the perinephric fat layer were depleted?

<p>The kidney would descend more than two vertebral bodies (A)</p> Signup and view all the answers

Which of these observations specifically helps to identify the kidney as a likely target organ for Martine’s symptoms?

<p>Feeling of a tennis ball rolling inside her (D)</p> Signup and view all the answers

Which group of individuals is most commonly affected by nephroptosis?

<p>Thin women (D)</p> Signup and view all the answers

What is the standard treatment for nephroptosis?

<p>Laparoscopic nephropexy (B)</p> Signup and view all the answers

What role does peritoneum play concerning the kidneys?

<p>Overlying membrane maintaining kidney position (D)</p> Signup and view all the answers

What condition is characterized by the kidney descending during postural movement?

<p>Nephroptosis (A)</p> Signup and view all the answers

Which layer surrounds the renal sinus of the kidney?

<p>Fibrous capsule (D)</p> Signup and view all the answers

What is the common symptom experienced during pregnancy associated with nephroptosis?

<p>Improvement of abdominal pain (B)</p> Signup and view all the answers

What anatomical feature of the kidney is described as the superficial region?

<p>Renal cortex (A)</p> Signup and view all the answers

Which of the following correctly describes the term 'floating kidney'?

<p>A kidney that moves significantly with posture changes (A)</p> Signup and view all the answers

What is the primary anatomical role of the renal columns within the kidney?

<p>To separate and support adjacent renal pyramids (D)</p> Signup and view all the answers

Which statement accurately describes the flow of blood from the renal artery?

<p>Renal artery → segmental → interlobar → cortical radiate (D)</p> Signup and view all the answers

What is the combined function of minor calyces in the kidney?

<p>To merge and transport urine to the major calyces (D)</p> Signup and view all the answers

What unique feature distinguishes the venous flow in the kidney?

<p>Absence of segmental veins (B)</p> Signup and view all the answers

Which structure serves as the site for the collection of urine before it moves to the ureter?

<p>Major calyx (A)</p> Signup and view all the answers

Which anatomical feature of the kidney is most critical for its blood supply?

<p>Hilum (B)</p> Signup and view all the answers

How does the arrangement of the kidney lobes contribute to its overall function?

<p>They facilitate blood flow and urine collection (B)</p> Signup and view all the answers

What is the significance of the renal pelvis in urine transport?

<p>It channels urine to the ureter (C)</p> Signup and view all the answers

What term best describes the conical structures found within the renal medulla?

<p>Renal pyramids (B)</p> Signup and view all the answers

Which part of the renal architecture is specifically dedicated to urine collection from lobes?

<p>Minor calyx (A)</p> Signup and view all the answers

Flashcards

Renal pyramid

A conical structure in the kidney's medulla.

Renal papilla

The tip of a renal pyramid, collecting urine.

Renal column

A part of the kidney that separates pyramids.

Kidney lobe

A kidney unit containing a pyramid, cortex and columns.

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Renal artery

Brings large amount of blood to the kidney.

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Renal vein

Takes blood away from the kidney.

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Renal blood flow pathway

Blood flows from renal, segmental, interlobar, arcuate, and cortical radiate arteries/veins.

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Renal pelvis

Funnel-shaped structure that collects urine from major calyces.

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Renal Nerve Supply

Network of autonomic nerve fibers and ganglia supplying kidneys and ureters.

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Renal Plexus

Network of autonomic nerve fibers and ganglia supplying kidneys and ureters, coming off the celiac plexus.

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Renal Blood Flow Regulation

Controlled by renal nerve supply, impacting blood flow to the kidneys.

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Renin Release Stimulation

Triggered by the renal nerve supply to help control blood pressure.

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Cortical Nephrons

85% of nephrons, primarily in the cortex, handling most kidney functions.

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Juxtamedullary Nephrons

15% of nephrons with long loops into the medulla, necessary for concentrated urine.

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Nephrons

Microscopic functional units in the kidney, approximately 1 million per kidney.

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Microscopic kidney features

Nephrons are the microscopic functional units of the kidneys that filter waste from the blood.

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Nephron Loop

The part of the nephron that extends deep into the medulla, crucial for water reabsorption.

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Concentrated Urine Production

Crucial role played by juxtamedullary nephrons in creating concentrated urine.

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What is filtration?

The process where blood pressure forces water and solutes out of glomerular capillaries into the capsular space.

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What is filtrate?

The protein-free fluid produced by filtration in the glomerulus, similar to blood plasma.

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Renal tubule

A long, tubular passageway that receives filtrate and modifies it to create urine.

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Glomerulus

A tuft of capillaries with fenestrated endothelium, allowing efficient filtrate formation.

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What are podocytes?

Branching epithelial cells in the glomerular capsule with extensions called foot processes that cling to the basement membrane.

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What is the parietal layer?

The outer layer of the glomerular capsule, composed of simple squamous epithelium.

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What is the visceral layer?

The inner layer of the glomerular capsule, consisting of podocytes that cling to the glomerular capillaries.

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What is the capsular space?

The space between the glomerulus and the glomerular capsule where filtrate collects.

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What is the function of the renal corpuscle?

The renal corpuscle is responsible for filtering blood and producing filtrate.

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How does filtrate differ from blood plasma?

Filtrate is similar to blood plasma but lacks proteins, due to the filtration process in the glomerulus.

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Nephron segment fluid flow

The direction of tubular fluid and interstitial fluid (peritubular fluid) changes in different nephron segments.

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Variable Reabsorption

Some regions of the nephron can regulate reabsorption of water and solutes based on hormonal signals.

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Collecting system function

A series of tubes that collect tubular fluid from the nephron and carry it away.

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Collecting duct cell types

Two main cell types in the collecting duct: intercalated cells (handle hydrogen/bicarbonate) and principal cells (reabsorb water/sodium, secrete potassium).

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Papillary duct function

Collects fluid from multiple collecting ducts and delivers it to the minor calyx.

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Kidney Location

The kidneys are located in the superior lumbar region, between the 12th thoracic vertebra (T12) and the 5th lumbar vertebra (L5).

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Kidney Position

The kidneys are retroperitoneal, meaning they lie behind the peritoneum (the lining of the abdominal cavity).

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Kidney Asymmetry

The right kidney is slightly lower than the left kidney due to the presence of the liver on the right side.

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What sits atop the kidney?

The adrenal (suprarenal) gland sits on top of each kidney like a little hat.

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Kidney Surface

The kidney has a convex lateral surface (outer side) and a concave medial surface (inner side).

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Renal Sinus

The renal sinus is the internal space within the kidney that is accessed through the renal hilum.

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Kidney Size and Shape

Each kidney is roughly 4 inches long, 2 inches wide, and weighs about 150 grams. They have a reddish-brown color.

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Kidney Connection to Bladder

The ureters, which carry urine from the kidneys, connect to the urinary bladder at its posterior, inferior surface.

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Kidney Protective Layers

The kidneys are protected by three layers of tissue: fibrous capsule, perirenal fat capsule, and renal fascia.

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Muscle twitch

A single, brief contraction of a muscle fiber (cell) in response to a single nerve impulse, generating tension. This is the fundamental unit of muscle activity.

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Muscle fiber types

Muscle fibers are classified into different types based on their characteristics, including contraction speed, fatigue resistance, and metabolic pathways. There are three main types: Slow Oxidative (SO), Fast Oxidative-Glycolytic (FOG), and Fast Glycolytic (FG) fibers.

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Slow Oxidative (SO) fibers

Muscle fibers that contract slowly, are highly resistant to fatigue, and rely mainly on aerobic respiration for energy. They are rich in mitochondria and myoglobin, giving them a red color.

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Fast Glycolytic (FG) fibers

Muscle fibers that contract quickly, fatigue rapidly, and rely mostly on anaerobic glycolysis for energy. They have fewer mitochondria and myoglobin, giving them a pale color.

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Fast Oxidative-Glycolytic (FOG) fibers

Muscle fibers that have intermediate characteristics between SO and FG fibers. They can contract quickly, are moderately fatigue-resistant, and utilize both aerobic and anaerobic pathways for energy.

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ATP hydrolysis by myosin ATPase

The rate at which myosin ATPase hydrolyzes ATP (a high-energy molecule) directly impacts the speed of muscle contraction. Slow fibers have slower ATP hydrolysis, while fast fibers have faster ATP hydrolysis.

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Creatine kinase

An enzyme that helps regenerate ATP in muscle fibers. Fast glycolytic (FG) fibers have the highest amount of creatine kinase, reflecting their reliance on anaerobic metabolism for rapid ATP production.

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Micturition

The process of urination, or the act of emptying the bladder.

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Martine's Symptoms

Intermittent right abdominal pain, worsened by standing upright and moving from supine to prone, relieved when lying down, exacerbated by alcohol and frequent urination.

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Exacerbating Factors

Martine's pain is exacerbated by standing upright, moving from supine to prone, alcohol consumption, and frequent urination.

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Kidney as Target

Martine's symptoms suggest the kidney as a possible source of pain due to its location in the right abdomen, pain worsened by movement, and potential connection to urination.

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Renal Medulla

The inner region of the kidney, containing renal pyramids and columns.

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Hilum

A medial indentation on the kidney where blood vessels, nerves, and ureters enter and exit.

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Minor Calyx

A cup-shaped structure collecting urine from a single kidney lobe.

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Major Calyx

Formed by the fusion of several minor calyces, collecting urine from multiple lobes.

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Renal Blood Supply

Kidneys receive a rich blood supply, filtering waste and regulating blood composition.

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Nephroptosis

A condition where the kidney descends abnormally during postural changes, often causing pain.

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Floating Kidney

A common description for nephroptosis, where the kidney descends more than 2 vertebral bodies (> 5 cm) with movement.

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Most common nephroptosis group

Thin women are more susceptible to nephroptosis, as the surrounding fat and support structures are reduced.

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Nephroptosis symptoms

Abdominal pain, often relieved by lying down, can indicate nephroptosis.

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Pregnancy and nephroptosis

Pregnancy can alleviate nephroptosis pain due to increased abdominal pressure.

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Definitive nephroptosis test

Imaging techniques like ultrasound or CT scan are key for making a definitive diagnosis.

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Nephroptosis treatment

Laparoscopic nephropexy is the standard procedure to fix nephroptosis.

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Kidney hilum structures

The renal artery, renal vein, and ureter all enter and exit the kidney through a central point called the hilum.

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Kidney connective tissue layers

The kidney is protected by three layers: fibrous capsule, perirenal fat capsule, and renal fascia.

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Kidney position change with fat loss

If perinephric fat is depleted and the fibrous capsule detaches, the kidney can migrate downward.

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Study Notes

Urinary System Overview

  • The urinary system comprises two kidneys, ureters, a urinary bladder, and a urethra.
  • Kidneys are major excretory organs, processing about 25% of cardiac output per minute.
  • Urine, water, and small molecule substances are filtered by the kidneys.
  • The urinary system produces and excretes urine by processing the blood.

Urinary System - Major Organs

  • Kidneys: Major excretory organs responsible for filtering blood and producing urine.
  • Ureters: Tubes that transport urine from the kidneys to the urinary bladder.
  • Urinary bladder: Stores urine until elimination.
  • Urethra: Tube through which urine is expelled from the body.

Urinary System - Functions

  • Regulate blood pressure: Maintaining adequate fluid balance influences blood volume.
  • Regulate plasma osmolarity and ionic balance: This includes electrolytes like sodium and potassium.
  • Regulate plasma pH: Kidneys maintain acid-base balance in the body.
  • Eliminate drugs and toxins: This includes excreting metabolic products and foreign substances.
  • Prevent loss of nutrients: Crucial for maintaining essential substances in the body.

Kidney Structure and Location

  • Location: Retroperitoneal (behind the peritoneum) in the superior lumbar region.
  • Structure: Kidney is reddish-brown, with an approximate size of 4 inches long by 2 inches wide.
  • Layers: The coverings are predominantly connective tissue, consisting of Fibrous capsule (innermost layer), Perirenal fat capsule (middle layer), and Renal fascia (outermost layer).
  • Hilum: Medial indentation where the ureters, renal blood vessels, lymphatics, and nerves enter and exit the kidney.

Kidney - Major Structural Features

  • Fibrous capsule: Lines the renal sinus, the internal cavity within the kidney.
  • Renal cortex: Superficial region of the kidney.
  • Renal medulla: Inner region containing renal pyramids.
  • Renal pyramids: Conical structures in the medulla, ending at the renal papilla.
  • Renal papilla: Tip of a renal pyramid.
  • Renal columns: Separating adjacent renal pyramids.
  • Kidney lobe: One renal pyramid plus the cortical tissue encompassing its base, and portions of the adjacent renal columns.

Kidney - Other Structural Features

  • Hilum: Medial indentation in the kidney.
  • Minor calyces: Collects urine from a single kidney lobe.
  • Major calyces: Forms from the fusion of 4-5 minor calyces.
  • Renal pelvis: Funnel-shaped structure that collects urine from major calyces.
  • Ureter: Continuous with the renal pelvis exiting the kidney collecting urine.

Renal Blood Supply

  • About one-fourth (1200 ml) of cardiac output is delivered to the kidneys each minute.
  • Arterial flow: renal → segmental → interlobar → arcuate → cortical radiate (interlobular).
  • Venous flow: cortical radiate → arcuate → interlobar → renal veins.

Renal Nerve Supply

  • The renal plexus is a network of autonomic nerve fibers and ganglia.
  • The renal plexus supplies the kidneys and ureters stemming from the celiac plexus.
  • The renal plexus regulates renal blood flow and stimulates the release of renin.

Nephron – Overview

  • Nephrons are the microscopic functional units of the kidney. Each kidney contains about 1 million nephrons.
  • There are two types of nephrons.
  • Cortical nephrons: Located primarily in the cortex and are the majority type.
  • Juxtamedullary nephrons: Located deep in the medulla with long nephron loops, which contribute to the production of concentrated urine.

Renal Corpuscle - Overview

  • The renal corpuscle consists of the glomerulus and Bowman's capsule.
  • Glomerulus: A tuft of capillaries where filtration occurs.
  • Bowman's capsule: Cup-shaped structure that surrounds the glomerulus, collecting the filtrate.

Nephron - Proximal Convoluted Tubule (PCT)

  • Reabsorbs nutrients from the filtrate (now called tubular fluid).
  • Allows optimum time for exchange of tubular fluid components.
  • Cuboidal cells arranged in a winding pattern in the DCT to maximize the time fluid interacts with the surrounding cells.

Nephron - Nephron Loop

  • U-shaped structure consisting of descending and ascending limbs.
  • Descending limb is lined by simple squamous epithelium, while the ascending limb has thick and thin segments.

Nephron - Distal Convoluted Tubule (DCT)

  • Cuboidal cells with few microvilli.
  • Plays a crucial role in regulating salt and water balance in the body.

Collecting System

  • Collecting ducts collect fluid from many nephrons and carry it through the renal medulla.
  • Lined with principal cells (reabsorb water and Na+, secrete K+) and intercalated cells (regulate hydrogen and bicarbonate ions.)
  • The papillary ducts deliver urine to the minor calyces.

Physiological Parameters for Effective Renal function

  • Blood pressure is a crucial factor in maintaining the proper flow of blood through the kidneys.
  • Adequate blood supply delivers necessary nutrients to the kidneys to support their function.
  • Hormonal control is essential in regulating processes like water and electrolyte reabsorption in different anatomical segments of the nephron.

Nephron- Segments

  • The direction of tubular fluid and the surrounding interstitial fluid (peritubular fluid) varies at each segment of the nephron.
  • Water and solutes are reabsorbed in different nephron segments. Hormonal control regulates water and electrolyte reabsorption in various parts of the nephron segments.

Case Study: The Pensive Paramedic

  • Martine, 32 years old, experiences intermittent right abdominal pain exacerbated by standing and relieved by lying down.
  • The pain is triggered by changing from a supine to a prone position and is exacerbated by alcohol consumption followed by frequent micturition.
  • This case study highlights a possible renal abnormality (possible nephroptosis) needing further investigation.

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Description

This quiz covers the key components and functions of the urinary system, including the roles of the kidneys, ureters, bladder, and urethra. Explore how these organs work together to filter blood, produce urine, and maintain body fluid balance.

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