Podcast
Questions and Answers
What happens to the number of nephrons as a person ages?
What happens to the number of nephrons as a person ages?
Which statement best describes the function of the glomerulus?
Which statement best describes the function of the glomerulus?
What distinguishes cortical nephrons from juxtamedullary nephrons?
What distinguishes cortical nephrons from juxtamedullary nephrons?
What occurs after fluid flows into Bowman's capsule?
What occurs after fluid flows into Bowman's capsule?
Signup and view all the answers
How is hydrostatic pressure in glomerular capillaries characterized?
How is hydrostatic pressure in glomerular capillaries characterized?
Signup and view all the answers
Which of the following structures is the last component before the renal pelvis?
Which of the following structures is the last component before the renal pelvis?
Signup and view all the answers
At what age does the decline in nephron number typically begin?
At what age does the decline in nephron number typically begin?
Signup and view all the answers
What is the role of the macula densa in the nephron?
What is the role of the macula densa in the nephron?
Signup and view all the answers
What is the primary structure through which blood enters the kidneys?
What is the primary structure through which blood enters the kidneys?
Signup and view all the answers
Which two major regions are found within the kidney?
Which two major regions are found within the kidney?
Signup and view all the answers
How much blood flow do the kidneys receive as a percentage of cardiac output?
How much blood flow do the kidneys receive as a percentage of cardiac output?
Signup and view all the answers
What is the role of the glomerular capillaries?
What is the role of the glomerular capillaries?
Signup and view all the answers
What is unique about renal circulation compared to other circulatory systems?
What is unique about renal circulation compared to other circulatory systems?
Signup and view all the answers
Where do the renal pyramids meet within the kidney?
Where do the renal pyramids meet within the kidney?
Signup and view all the answers
What causes rapid fluid filtration in the glomerular capillaries?
What causes rapid fluid filtration in the glomerular capillaries?
Signup and view all the answers
What benefit does low hydrostatic pressure in tubular capillaries provide?
What benefit does low hydrostatic pressure in tubular capillaries provide?
Signup and view all the answers
What happens to substances that are freely filtered at the glomerulus but neither reabsorbed nor secreted?
What happens to substances that are freely filtered at the glomerulus but neither reabsorbed nor secreted?
Signup and view all the answers
Which of the following substances is likely to be partially reabsorbed after being filtered?
Which of the following substances is likely to be partially reabsorbed after being filtered?
Signup and view all the answers
What characterizes substances that are filtered at the glomerulus but not present in the urine?
What characterizes substances that are filtered at the glomerulus but not present in the urine?
Signup and view all the answers
Which statement best describes the handling of acids in the nephron?
Which statement best describes the handling of acids in the nephron?
Signup and view all the answers
What is the primary formula that illustrates how substances are handled by the nephron?
What is the primary formula that illustrates how substances are handled by the nephron?
Signup and view all the answers
Which of the following substances is highly reabsorbed, resulting in a small amount appearing in the urine?
Which of the following substances is highly reabsorbed, resulting in a small amount appearing in the urine?
Signup and view all the answers
How does tubular reabsorption compare to tubular secretion in the process of urine formation?
How does tubular reabsorption compare to tubular secretion in the process of urine formation?
Signup and view all the answers
Which best describes the fate of waste products like creatinine in the nephron?
Which best describes the fate of waste products like creatinine in the nephron?
Signup and view all the answers
What initiates peristaltic contractions in the ureters?
What initiates peristaltic contractions in the ureters?
Signup and view all the answers
How does the sympathetic nervous system affect peristaltic contractions in the ureters?
How does the sympathetic nervous system affect peristaltic contractions in the ureters?
Signup and view all the answers
What occurs when the stretch reflex in the bladder is activated?
What occurs when the stretch reflex in the bladder is activated?
Signup and view all the answers
What is the primary role of the higher centers in the cerebral cortex related to urination?
What is the primary role of the higher centers in the cerebral cortex related to urination?
Signup and view all the answers
What is the result of voluntary urination?
What is the result of voluntary urination?
Signup and view all the answers
What is NOT a process involved in urine excretion?
What is NOT a process involved in urine excretion?
Signup and view all the answers
What happens to urine composition after it enters the renal pelvis?
What happens to urine composition after it enters the renal pelvis?
Signup and view all the answers
How much urine typically remains in the bladder after complete emptying?
How much urine typically remains in the bladder after complete emptying?
Signup and view all the answers
What is the primary function of the vasa recta in the kidney?
What is the primary function of the vasa recta in the kidney?
Signup and view all the answers
What initiates the attrition reflex in the urinary bladder?
What initiates the attrition reflex in the urinary bladder?
Signup and view all the answers
Which part of the bladder is primarily responsible for collecting urine?
Which part of the bladder is primarily responsible for collecting urine?
Signup and view all the answers
What allows action potentials to spread quickly throughout the smooth muscle of the bladder?
What allows action potentials to spread quickly throughout the smooth muscle of the bladder?
Signup and view all the answers
What role does the internal sphincter play in bladder function?
What role does the internal sphincter play in bladder function?
Signup and view all the answers
Which nerves are primarily responsible for the innervation of the bladder?
Which nerves are primarily responsible for the innervation of the bladder?
Signup and view all the answers
What type of muscle is the external sphincter of the bladder?
What type of muscle is the external sphincter of the bladder?
Signup and view all the answers
How do sympathetic fibers affect the bladder?
How do sympathetic fibers affect the bladder?
Signup and view all the answers
Which of the following waste products are eliminated from the body primarily by the kidneys?
Which of the following waste products are eliminated from the body primarily by the kidneys?
Signup and view all the answers
What is the primary stimulus for erythropoietin secretion in individuals with severe kidney disease?
What is the primary stimulus for erythropoietin secretion in individuals with severe kidney disease?
Signup and view all the answers
What is the primary role of the kidneys in regulating arterial blood pressure?
What is the primary role of the kidneys in regulating arterial blood pressure?
Signup and view all the answers
Which of the following hormones is produced by the kidneys and is essential for calcium absorption from the gastrointestinal tract?
Which of the following hormones is produced by the kidneys and is essential for calcium absorption from the gastrointestinal tract?
Signup and view all the answers
What is the role of the kidneys in maintaining acid-base balance?
What is the role of the kidneys in maintaining acid-base balance?
Signup and view all the answers
Why does an increase in sodium intake lead to a temporary increase in cellular fluid volume?
Why does an increase in sodium intake lead to a temporary increase in cellular fluid volume?
Signup and view all the answers
Which of the following is NOT a function of the kidneys?
Which of the following is NOT a function of the kidneys?
Signup and view all the answers
What is the primary function of the kidneys?
What is the primary function of the kidneys?
Signup and view all the answers
Flashcards
Functions of Kidneys
Functions of Kidneys
The kidneys filter plasma, remove waste, and regulate body fluids.
Waste Products
Waste Products
Includes urea, creatinine, uric acid, bilirubin, and hormone metabolites.
Homeostasis
Homeostasis
The kidneys adjust excretion rates to match fluid and electrolyte intake.
Erythropoietin
Erythropoietin
Signup and view all the flashcards
Acid-Base Regulation
Acid-Base Regulation
Signup and view all the flashcards
Vitamin D Activation
Vitamin D Activation
Signup and view all the flashcards
Gluconeogenesis
Gluconeogenesis
Signup and view all the flashcards
Electrolyte Regulation
Electrolyte Regulation
Signup and view all the flashcards
Vasa Recta
Vasa Recta
Signup and view all the flashcards
Attrition Reflex
Attrition Reflex
Signup and view all the flashcards
Bladder Body
Bladder Body
Signup and view all the flashcards
Bladder Neck
Bladder Neck
Signup and view all the flashcards
Internal Sphincter
Internal Sphincter
Signup and view all the flashcards
External Sphincter
External Sphincter
Signup and view all the flashcards
Pelvic Nerves
Pelvic Nerves
Signup and view all the flashcards
Parasympathetic Innovation
Parasympathetic Innovation
Signup and view all the flashcards
Kidney Structure
Kidney Structure
Signup and view all the flashcards
Hilum
Hilum
Signup and view all the flashcards
Cortex and Medulla
Cortex and Medulla
Signup and view all the flashcards
Renal Pyramids
Renal Pyramids
Signup and view all the flashcards
Renal Pelvis
Renal Pelvis
Signup and view all the flashcards
Blood Flow to Kidneys
Blood Flow to Kidneys
Signup and view all the flashcards
Glomerular Filtration
Glomerular Filtration
Signup and view all the flashcards
Peritubular Capillaries
Peritubular Capillaries
Signup and view all the flashcards
Ureters
Ureters
Signup and view all the flashcards
Peristaltic contractions
Peristaltic contractions
Signup and view all the flashcards
Stretch reflex in bladder
Stretch reflex in bladder
Signup and view all the flashcards
Positive feedback loop
Positive feedback loop
Signup and view all the flashcards
Urine excretion calculation
Urine excretion calculation
Signup and view all the flashcards
Bowman's capsule
Bowman's capsule
Signup and view all the flashcards
Smooth muscle innervation
Smooth muscle innervation
Signup and view all the flashcards
Hydrostatic Pressure
Hydrostatic Pressure
Signup and view all the flashcards
Nephrons
Nephrons
Signup and view all the flashcards
Glomerulus
Glomerulus
Signup and view all the flashcards
Loop of Henle
Loop of Henle
Signup and view all the flashcards
Macula Densa
Macula Densa
Signup and view all the flashcards
Cortical Nephrons
Cortical Nephrons
Signup and view all the flashcards
Juxtamedullary Nephrons
Juxtamedullary Nephrons
Signup and view all the flashcards
Nephron function
Nephron function
Signup and view all the flashcards
Excretion rate
Excretion rate
Signup and view all the flashcards
Creatinine handling
Creatinine handling
Signup and view all the flashcards
Partial reabsorption
Partial reabsorption
Signup and view all the flashcards
Glucose reabsorption
Glucose reabsorption
Signup and view all the flashcards
Secretion in nephron
Secretion in nephron
Signup and view all the flashcards
Excretion formula
Excretion formula
Signup and view all the flashcards
Importance of reabsorption
Importance of reabsorption
Signup and view all the flashcards
Study Notes
Urinary System and Kidney Function
- Kidneys filter plasma, removing waste and regulating: water balance, electrolyte balance, body fluid osmolality, electrolyte concentrations, arterial pressure, acid-base balance, erythrocyte production, hormone secretion, metabolism, and excretion, and gluconeogenesis.
- Kidneys eliminate metabolic wastes (urea, creatine, uric acid, bilirubin, hormones).
- Water and electrolyte excretion rates adjust to match intake for homeostasis.
- Kidneys regulate sodium, chloride, potassium, calcium, hydrogen, magnesium, and phosphate.
- Kidneys are critical for long-term arterial blood pressure regulation.
- Kidneys help regulate acid-base balance, alongside lungs and buffer system.
- Kidneys produce erythropoietin to stimulate red blood cell production. Hypoxia is a main stimulus.
- Kidneys produce 1-5 hydroxyvitamin D3 (active form of vitamin D) essential for calcium deposition in bone and calcium reabsorption.
- Kidneys perform gluconeogenesis (glucose synthesis from amino acids) during prolonged fasting.
Kidney Anatomy and Structure
- Kidneys lie on posterior abdominal wall, weighing ~150g each.
- Size of a clenched fist, medial side has hilum (where renal artery, vein, lymphatics, nerve supply pass).
- Two main regions: outer cortex, inner medulla, divided into pyramids.
- Pyramid bases at cortex-medulla border, tips (papillae) collect urine.
- Urine collected by minor calices, then major calices, forming renal pelvis.
- Urine travels to bladder via ureters.
Renal Blood Flow and Filtration
- ~22% cardiac output flows to kidneys (~1100 ml/min).
- Renal artery branches, forming interlobar, arcuate, and interlobular arteries, leading afferent arterioles and glomerular capillaries.
- Glomeruli filter large amounts of fluid and solutes, starting urine formation.
- Filtered fluid flows to peri-tubular capillaries, surrounding renal tubules.
- High glomerular hydrostatic pressure drives rapid filtration.
- Adjustments to afferent and efferent arterioles regulate hydrostatic pressure for tubular reabsorption.
Nephron Structure and Function
- Each kidney has ~800,000-1,000,000 nephrons.
- Nephron consists of glomerulus (capillary network) and a long tubule.
- Bowman's capsule surrounds glomerulus, collecting filtered fluid.
- Filtered fluid moves into proximal tubule, then loop of Henle (descending/ascending limbs), distal tubule, and collecting duct.
- Loop of Henle includes specialized cells (macula densa) for regulating reabsorption/secretion.
Urine Formation
- Glomerular filtration, tubular reabsorption, and tubular secretion.
- Substances can be freely filtered, reabsorbed, or secreted.
- Kidney functions to make urine and maintaining homeostasis by filtering, regulating, or excreting substances to maintain healthy levels.
- Urinary excretion = filtration - reabsorption + secretion.
Kidney Function Summary
- Important in removing waste products from the body, maintaining fluid and electrolyte balance, and regulating blood pressure.
- Filtration rate (180L/day) allows processing plasma ~60 times daily
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Related Documents
Description
Test your knowledge on the urinary system and the crucial role of the kidneys in filtering blood, maintaining homeostasis, and regulating various bodily functions. This quiz covers aspects such as waste elimination, electrolyte balance, and hormone secretion. Discover how kidneys contribute to overall health and metabolic processes.