Podcast
Questions and Answers
What is one of the key functions of the kidneys in maintaining the body's internal environment?
What is one of the key functions of the kidneys in maintaining the body's internal environment?
Which of the following is NOT a function of the kidneys?
Which of the following is NOT a function of the kidneys?
What structure primarily transports urine from the kidneys to the urinary bladder?
What structure primarily transports urine from the kidneys to the urinary bladder?
Which of the following describes the renal medulla?
Which of the following describes the renal medulla?
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Which layer of supportive tissue is described as a fatty cushion surrounding the kidney?
Which layer of supportive tissue is described as a fatty cushion surrounding the kidney?
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Where are the kidneys located in relation to the spinal column?
Where are the kidneys located in relation to the spinal column?
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What is the renal hilum?
What is the renal hilum?
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What is the approximate number of lobes present in one kidney?
What is the approximate number of lobes present in one kidney?
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What is the correct sequence of urine flow through the structures of the kidney?
What is the correct sequence of urine flow through the structures of the kidney?
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Which part of the nephron is primarily responsible for urine filtration?
Which part of the nephron is primarily responsible for urine filtration?
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What structure collects urine from minor calyces?
What structure collects urine from minor calyces?
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How do cortical nephrons differ from juxtamedullary nephrons?
How do cortical nephrons differ from juxtamedullary nephrons?
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What is the primary function of the macula densa cells in the juxtaglomerular complex?
What is the primary function of the macula densa cells in the juxtaglomerular complex?
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Which blood vessel carries blood away from the glomerulus?
Which blood vessel carries blood away from the glomerulus?
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What percentage of cardiac output is delivered to the kidneys at rest?
What percentage of cardiac output is delivered to the kidneys at rest?
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Where is most of the reabsorption and secretion in a nephron primarily located?
Where is most of the reabsorption and secretion in a nephron primarily located?
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What defines the structure of the renal corpuscle?
What defines the structure of the renal corpuscle?
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Which statement accurately reflects urine production?
Which statement accurately reflects urine production?
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What is the role of principal cells in the collecting duct?
What is the role of principal cells in the collecting duct?
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What are peritubular capillaries primarily adapted for?
What are peritubular capillaries primarily adapted for?
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Which process occurs first in urine formation?
Which process occurs first in urine formation?
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Functionally, what do vasa recta contribute to in the nephron?
Functionally, what do vasa recta contribute to in the nephron?
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What is the primary component of urine?
What is the primary component of urine?
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What might cause urine to have a cloudy appearance?
What might cause urine to have a cloudy appearance?
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What is the normal pH range of urine?
What is the normal pH range of urine?
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What may indicate the presence of renal calculi?
What may indicate the presence of renal calculi?
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Which part of the ureter is primarily responsible for preventing backflow of urine?
Which part of the ureter is primarily responsible for preventing backflow of urine?
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Which dietary factor can lead to an increase in urine pH?
Which dietary factor can lead to an increase in urine pH?
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What is one common treatment for kidney stones?
What is one common treatment for kidney stones?
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What is the specific gravity range of urine?
What is the specific gravity range of urine?
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What is the primary function of the urinary bladder?
What is the primary function of the urinary bladder?
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Which layer is responsible for the contraction of the urinary bladder during urination?
Which layer is responsible for the contraction of the urinary bladder during urination?
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What type of sphincter is the internal urethral sphincter?
What type of sphincter is the internal urethral sphincter?
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Which symptom is commonly associated with urinary tract infections (UTIs)?
Which symptom is commonly associated with urinary tract infections (UTIs)?
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Which condition occurs when the bladder is unable to expel urine?
Which condition occurs when the bladder is unable to expel urine?
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What is the typical length of the female urethra?
What is the typical length of the female urethra?
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Which type of incontinence is triggered by increased intra-abdominal pressure?
Which type of incontinence is triggered by increased intra-abdominal pressure?
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What is the primary cause of urinary tract infections in women?
What is the primary cause of urinary tract infections in women?
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By age 80, approximately what percentage of glomerular filtration rate (GFR) remains compared to young adults?
By age 80, approximately what percentage of glomerular filtration rate (GFR) remains compared to young adults?
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What triggers the events during micturition?
What triggers the events during micturition?
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What type of cell division is responsible for producing gametes?
What type of cell division is responsible for producing gametes?
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Which cells are considered female gametes?
Which cells are considered female gametes?
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What is the chromosome composition of human gametes?
What is the chromosome composition of human gametes?
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During which process do gametes unite to initiate the formation of a new individual?
During which process do gametes unite to initiate the formation of a new individual?
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What function do sex chromosomes serve in humans?
What function do sex chromosomes serve in humans?
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What distinguishes meiosis from mitosis?
What distinguishes meiosis from mitosis?
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What is the significance of crossing over during meiosis?
What is the significance of crossing over during meiosis?
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What is the total chromosome number in a diploid human cell?
What is the total chromosome number in a diploid human cell?
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What is the final stage of spermatogenesis called?
What is the final stage of spermatogenesis called?
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Which cell type remains at the basal lamina as a stem cell during spermatogenesis?
Which cell type remains at the basal lamina as a stem cell during spermatogenesis?
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What structure forms above the nucleus of a spermatid during spermiogenesis?
What structure forms above the nucleus of a spermatid during spermiogenesis?
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What is the role of mitochondria in the mature spermatozoon?
What is the role of mitochondria in the mature spermatozoon?
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How many sperm are produced from one primary spermatocyte undergoing spermatogenesis?
How many sperm are produced from one primary spermatocyte undergoing spermatogenesis?
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What characterizes a mature (large vesicular) follicle in ovarian follicle development?
What characterizes a mature (large vesicular) follicle in ovarian follicle development?
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What happens to the primary oocyte in a primordial follicle?
What happens to the primary oocyte in a primordial follicle?
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What hormone is primarily secreted by granulosa cells during the maturation of ovarian follicles?
What hormone is primarily secreted by granulosa cells during the maturation of ovarian follicles?
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What is the fate of the corpus luteum after the oocyte is expelled during ovulation?
What is the fate of the corpus luteum after the oocyte is expelled during ovulation?
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What is the typical outcome of female gametogenesis in terms of viable gametes produced?
What is the typical outcome of female gametogenesis in terms of viable gametes produced?
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During which phase of meiosis does crossing over occur?
During which phase of meiosis does crossing over occur?
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How many chromosomes does each daughter cell have after Meiosis I?
How many chromosomes does each daughter cell have after Meiosis I?
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What is the primary result of independent assortment during meiosis?
What is the primary result of independent assortment during meiosis?
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What process occurs during Meiosis II?
What process occurs during Meiosis II?
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What occurs during telophase I and cytokinesis?
What occurs during telophase I and cytokinesis?
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What may result from nondisjunction during meiosis?
What may result from nondisjunction during meiosis?
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What is the primary function of spermatogonia in spermatogenesis?
What is the primary function of spermatogonia in spermatogenesis?
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In females, what do secondary oocytes mature into?
In females, what do secondary oocytes mature into?
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What is the result of successful crossing over during meiosis?
What is the result of successful crossing over during meiosis?
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What is the outcome of meiosis in terms of the number of daughter cells produced?
What is the outcome of meiosis in terms of the number of daughter cells produced?
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What happens during anaphase II of meiosis?
What happens during anaphase II of meiosis?
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At what stage does the process of spermiogenesis occur during spermatogenesis?
At what stage does the process of spermiogenesis occur during spermatogenesis?
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What is a characteristic of fraternal twins compared to identical twins?
What is a characteristic of fraternal twins compared to identical twins?
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Which cellular event defines the transition from meiosis I to meiosis II?
Which cellular event defines the transition from meiosis I to meiosis II?
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What is the fate of the polar body formed during oogenesis?
What is the fate of the polar body formed during oogenesis?
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During which phase of the ovarian cycle does the primary oocyte complete meiosis I?
During which phase of the ovarian cycle does the primary oocyte complete meiosis I?
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What occurs to the secondary oocyte if it is not fertilized?
What occurs to the secondary oocyte if it is not fertilized?
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Which hormone primarily stimulates the maturation of primordial follicles from puberty to menopause?
Which hormone primarily stimulates the maturation of primordial follicles from puberty to menopause?
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What is the status of primary oocytes in the ovaries before birth?
What is the status of primary oocytes in the ovaries before birth?
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Which method of contraception involves surgically cutting and tying off the uterine tubes?
Which method of contraception involves surgically cutting and tying off the uterine tubes?
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What is a common risk factor for breast cancer that is associated with increased estrogen exposure?
What is a common risk factor for breast cancer that is associated with increased estrogen exposure?
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Which of the following sexually transmitted infections is caused by a bacterium and can be asymptomatic in many individuals?
Which of the following sexually transmitted infections is caused by a bacterium and can be asymptomatic in many individuals?
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What is the purpose of barrier methods in contraception?
What is the purpose of barrier methods in contraception?
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What does the morning-after pill primarily inhibit?
What does the morning-after pill primarily inhibit?
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Which of the following is NOT a symptom commonly associated with chlamydia?
Which of the following is NOT a symptom commonly associated with chlamydia?
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In older males, what hormonal change primarily contributes to benign prostatic hyperplasia?
In older males, what hormonal change primarily contributes to benign prostatic hyperplasia?
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What are the flexible plastic structures inserted into the uterus called?
What are the flexible plastic structures inserted into the uterus called?
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What is the primary treatment for endometriosis aimed at suppressing the growth of endometrial tissue?
What is the primary treatment for endometriosis aimed at suppressing the growth of endometrial tissue?
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Which sexually transmitted infection is characterized by cyclic outbreaks of blister formation?
Which sexually transmitted infection is characterized by cyclic outbreaks of blister formation?
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Which procedure permanently prevents sperm from being able to exit the testis?
Which procedure permanently prevents sperm from being able to exit the testis?
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What common breast cancer screening method is recommended for women over 40?
What common breast cancer screening method is recommended for women over 40?
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What complication can arise in women due to untreated sexually transmitted infections?
What complication can arise in women due to untreated sexually transmitted infections?
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What is the characteristic feature of prostate cancer in its early stages?
What is the characteristic feature of prostate cancer in its early stages?
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What occurs during the follicular phase of the ovarian cycle?
What occurs during the follicular phase of the ovarian cycle?
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What triggers ovulation in the ovarian cycle?
What triggers ovulation in the ovarian cycle?
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What does the corpus luteum primarily secrete during the luteal phase?
What does the corpus luteum primarily secrete during the luteal phase?
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What occurs if the secondary oocyte is not fertilized?
What occurs if the secondary oocyte is not fertilized?
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Which phase of the uterine cycle aligns with the ovarian luteal phase?
Which phase of the uterine cycle aligns with the ovarian luteal phase?
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During which phase of the ovarian cycle does the secondary oocyte reach metaphase II?
During which phase of the ovarian cycle does the secondary oocyte reach metaphase II?
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What is the typical age range for the onset of menopause?
What is the typical age range for the onset of menopause?
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What signifies the end of the luteal phase?
What signifies the end of the luteal phase?
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What hormone is secreted by a pre-embryo after fertilization?
What hormone is secreted by a pre-embryo after fertilization?
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Which type of cancer is the fifth most common in women?
Which type of cancer is the fifth most common in women?
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What is the role of the corpus luteum if the oocyte is fertilized?
What is the role of the corpus luteum if the oocyte is fertilized?
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What occurs during the menstrual phase of the uterine cycle?
What occurs during the menstrual phase of the uterine cycle?
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What characterizes the secretory phase of the uterine cycle?
What characterizes the secretory phase of the uterine cycle?
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Flashcards
Kidney Function
Kidney Function
Kidneys maintain internal balance by regulating water, solutes, and acid-base levels; excreting waste and producing hormones.
Kidney Location
Kidney Location
Located in the superior lumbar region, between vertebrae T12 and L5; retroperitoneal.
Renal Cortex
Renal Cortex
Outermost region of the kidney; light-colored and granular.
Renal Medulla
Renal Medulla
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Renal Pyramid
Renal Pyramid
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Kidney Support Layers
Kidney Support Layers
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Urinary System Parts
Urinary System Parts
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Kidney Hormones
Kidney Hormones
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Renal Pelvis
Renal Pelvis
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Minor Calyx
Minor Calyx
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Major Calyx
Major Calyx
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Nephron
Nephron
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Renal Corpuscle
Renal Corpuscle
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Glomerulus
Glomerulus
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Glomerular Capsule
Glomerular Capsule
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Proximal Convoluted Tubule (PCT)
Proximal Convoluted Tubule (PCT)
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Nephron Loop
Nephron Loop
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Distal Convoluted Tubule (DCT)
Distal Convoluted Tubule (DCT)
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Collecting Duct
Collecting Duct
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Cortical Nephrons
Cortical Nephrons
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Juxtamedullary Nephrons
Juxtamedullary Nephrons
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Peritubular Capillaries
Peritubular Capillaries
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Vasa Recta
Vasa Recta
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Urine composition
Urine composition
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Abnormal urine
Abnormal urine
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What does urine color tell us?
What does urine color tell us?
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Urine pH
Urine pH
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Specific gravity of urine
Specific gravity of urine
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Ureter function
Ureter function
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Kidney stones
Kidney stones
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How are kidney stones treated?
How are kidney stones treated?
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Trigone
Trigone
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Detrusor Muscle
Detrusor Muscle
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Internal Urethral Sphincter
Internal Urethral Sphincter
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External Urethral Sphincter
External Urethral Sphincter
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Urethritis
Urethritis
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Cystitis
Cystitis
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Pyelitis
Pyelitis
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Micturition
Micturition
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Stress Incontinence
Stress Incontinence
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Overflow Incontinence
Overflow Incontinence
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Gametes
Gametes
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Meiosis
Meiosis
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Homologous Chromosomes
Homologous Chromosomes
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Crossing Over
Crossing Over
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Autosomes
Autosomes
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Sex Chromosomes
Sex Chromosomes
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Haploid Cell
Haploid Cell
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Spermatogenesis
Spermatogenesis
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Spermiogenesis
Spermiogenesis
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Acrosome Cap
Acrosome Cap
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Spermatogonium
Spermatogonium
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Primary Spermatocyte
Primary Spermatocyte
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Secondary Spermatocyte
Secondary Spermatocyte
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Late Spermatid
Late Spermatid
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Follicle Cells
Follicle Cells
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Corpus Luteum
Corpus Luteum
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Antrum
Antrum
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What is oogenesis?
What is oogenesis?
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What happens to primary oocytes before birth?
What happens to primary oocytes before birth?
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What happens to primary oocytes during puberty?
What happens to primary oocytes during puberty?
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What happens to the primary oocyte in the vesicular follicle?
What happens to the primary oocyte in the vesicular follicle?
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What happens to the secondary oocyte after meiosis I?
What happens to the secondary oocyte after meiosis I?
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Endometriosis
Endometriosis
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Contraception
Contraception
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Abstinence
Abstinence
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Barrier Method
Barrier Method
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Intrauterine Device (IUD)
Intrauterine Device (IUD)
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Oral Contraceptives
Oral Contraceptives
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Tubal Ligation
Tubal Ligation
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Vasectomy
Vasectomy
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Breast Cancer Risk Factors
Breast Cancer Risk Factors
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Benign Prostatic Hyperplasia (BPH)
Benign Prostatic Hyperplasia (BPH)
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Prostate Cancer
Prostate Cancer
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Sexually Transmitted Infections (STIs)
Sexually Transmitted Infections (STIs)
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Chlamydia
Chlamydia
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Genital Herpes
Genital Herpes
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Gonorrhea
Gonorrhea
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Follicular Phase
Follicular Phase
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Ovulation
Ovulation
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Luteal Phase
Luteal Phase
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Menopause
Menopause
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Pre-Embryo
Pre-Embryo
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Human Chorionic Gonadotropin (hCG)
Human Chorionic Gonadotropin (hCG)
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Cervical Cancer
Cervical Cancer
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Pap Smear
Pap Smear
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Uterine Cycle
Uterine Cycle
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Menstrual Phase
Menstrual Phase
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Proliferative Phase
Proliferative Phase
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Secretory Phase
Secretory Phase
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Ovarian Cycle and Uterine Cycle Relationship
Ovarian Cycle and Uterine Cycle Relationship
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Study Notes
Kidney Function
- Kidneys are major excretory organs, maintaining internal body environment by regulating water volume and solute concentration in blood, ion concentrations in extracellular fluids, and long-term acid-base balance.
- They excrete metabolic wastes, toxins, and drugs.
- Kidneys produce erythropoietin (regulates red blood cell production) and renin (regulates blood pressure).
- They convert vitamin D to its active form and carry out gluconeogenesis as needed.
Urinary System Components
- Ureters: Transport urine from kidneys to bladder.
- Urinary bladder: Temporarily stores urine.
- Urethra: Transports urine out of the body.
Kidney Location and Structure
- Retroperitoneal, in superior lumbar region between T12 and L5.
- Right kidney is lower than left due to liver position.
- Adrenal gland sits atop each kidney.
- Kidney has convex lateral surface and concave medial surface with renal hilum (where vessels, nerves, and ureters enter/exit).
- Three supportive tissue layers surround the kidney:
- Renal fascia: Anchoring outer layer of dense fibrous connective tissue.
- Perirenal fat capsule: Fatty cushion.
- Fibrous capsule: Transparent capsule preventing infection spread.
Kidney Internal Anatomy
- Renal cortex: Superficial region, light-colored and granular appearance.
- Renal medulla: Deep to cortex, darker, reddish-brown appearance, composed of medullary pyramids.
- Pyramid base faces cortex, tip (papilla) faces internal space.
- Pyramids are separated by renal columns, extensions of cortical tissue.
- Lobe: Medullary pyramid and surrounding cortical tissue (approx. 8 per kidney).
- Renal pelvis: Funnel-shaped tube continuous with the ureter leaving the hilum.
- Branches of pelvis form 2-3 major calyces, which subdivide to form several minor calyces.
- Minor calyces: cup-shaped collecting urine from papillae.
- Major calyces: Collect urine from minor calyces and drain into renal pelvis.
- Urine flow: Papillae to minor calyx to major calyx to renal pelvis to ureter.
Kidney Blood Supply
- Kidneys have a rich blood supply as they cleanse blood and adjust composition.
- Renal arteries branch from the abdominal aorta, delivering ~1/4 of total cardiac output (~1200 mL/min) to kidneys at rest.
- Blood flow: Renal artery -> segmental -> interlobar -> arcuate -> cortical radiate arteries.
- Blood flows through microscopic vessels before draining into veins.
- Venous flow: Cortical radiate -> arcuate -> interlobar -> renal veins.
- Renal veins drain into the inferior vena cava.
Nephron Structure
- Nephrons are the functional units (over 1 million per kidney) that form urine.
- Each nephron has two main parts: renal corpuscle and renal tubule.
- Most of the corpuscle and tubule reside in the cortex.
Renal Corpuscle
- Glomerulus: Ball of capillaries with fenestrated endothelium, allowing filtrate (plasma-derived fluid) formation.
- Glomerular capsule: Cup-shaped hollow structure around glomerulus.
- Parietal layer: Simple squamous epithelium.
- Visceral layer: Podocytes clinging to glomerular capillaries.
Renal Tubule
- Proximal convoluted tubule: Close to corpuscle, confined to cortex, and has dense microvilli increasing surface area; reabsorption and secretion occur there.
- Nephron loop: U-shaped structure with descending and ascending limbs.
- Distal convoluted tubule: Farthest from corpuscle, confined to cortex, fewer microvilli (more secretion than reabsorption).
- Distal convoluted tubule drains into collecting duct.
- Collecting duct: Receives filtrate from many nephrons, runs through medullary pyramids, and gives them striped appearance. Fuses to deliver urine through papillae to minor calyces.
Nephron Classes
- Cortical nephrons: Primarily in cortex, constituting 85% of nephrons.
- Juxtamedullary nephrons: Have long loops that deeply invade medulla, crucial for concentrated urine production.
Nephron Capillary Beds
- Renal tubules are associated with glomerulus and peritubular capillaries/vasa recta.
- Glomerulus: Specialized for filtration, fed/drained by arterioles (afferent enters, efferent leaves).
- Peritubular capillaries: Clinging to renal tubules in cortex, low-pressure and porous for water/solute absorption (arise from efferent arterioles and empty into venules).
- Vasa recta: Long vessels parallel to nephron loops of juxtamedullary nephrons in medulla, crucial for concentrated urine.
Juxtaglomerular Complex (JGC)
- Each nephron has one JGC, involving modified portions of distal ascending limb of nephron loop and afferent arteriole.
- Important in regulating filtrate formation rate and blood pressure.
- Macula densa: Tall cells of ascending limb that detect NaCl content in filtrate (chemoreceptors).
- Granular cells: Enlarged, smooth muscle cells of afferent arteriole acting as mechanoreceptors sensing blood pressure; contain renin-containing secretory granules.
Kidney Physiology
- Kidneys filter entire plasma volume ~60 times/day (~180 L processed daily).
- Consume 20-25% of body's resting oxygen.
- Filtrate is blood plasma minus proteins; urine is produced from filtrate.
- Urine formation/blood adjustment involves three processes:
- Glomerular filtration: Produces cell/protein-free filtrate.
- Tubular reabsorption: Returns > 99% of filtrate substances to blood.
- Tubular secretion: Selectively moves substances from blood to filtrate.
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Description
This quiz covers the essential functions of the kidneys as excretory organs, their role in maintaining the body's internal environment, and the components of the urinary system. It also explores the anatomy of kidneys, including their location and structure. Test your knowledge on these critical aspects of human physiology.