Urethritis & Cervicitis: Chlamydia, Gonorrhoea, & NGU

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52 Questions

What percentage of individuals with chlamydial infection are asymptomatic?

The majority

What is the highest prevalence of genital chlamydia infection in?

15-24 year-olds

What is the primary cause of chlamydial infection?

Chlamydia trachomatis

What is a common symptom of chlamydial infection in women?

Lower abdominal pain

What is the typical presentation of rectal chlamydia infection?

Asymptomatic

What is the rate of pharyngeal chlamydia infection in MSM?

0.5-2.3%

What percentage of patients with recurrent disease experience lymphadenitis?

30%

What is a common complication of lesions in the second week of progression?

Superinfection with candida and streptococcal species

What is the dose and frequency of Aciclovir for recurrent disease?

800mg bd 5 days

How long does the chancre of primary syphilis typically resolve over?

3-8 weeks

What percentage of patients with primary syphilis will develop secondary syphilis if left untreated?

25%

What is a characteristic of the rash in secondary syphilis?

It is widespread and may be itchy

What is the primary mode of acquiring conjunctivitis in adults?

Sexual contact

What is the typical presentation of chlamydial conjunctivitis in adults?

Unilateral chronic, low-grade irritation

What is the most common complication of chlamydial conjunctivitis in women?

PID

What is the primary method of diagnosis for symptomatic women?

Gram or wet film examination

What is the antibiotic susceptibility trend of N. gonococcus patients from 2001 to 2007?

Decreased susceptibility to ciprofloxacin

What is the recommended treatment for pregnant women?

Intravaginal treatment for 7 days

What is the cure rate for topical and oral azoles in uncomplicated cases?

Over 70%

What is the primary cause of abnormal discharge in women of childbearing age?

Bacterial vaginosis

What is the characteristic pH of vaginal fluid in bacterial vaginosis?

pH 4.5-6.0

Why is speciation to albicans/non-albicans essential?

If complicated disease is suspected or present

What is the primary risk factor for bacterial vaginosis?

All of the above

What is the recommended treatment for recurrent VC?

Oral fluconazole every 72 hours for 3 doses then once a week for 6 months

What is the Whiff test used to diagnose?

Bacterial vaginosis

What is the goal of general advice for VC?

To improve vulval health

What is the primary cause of vulvovaginal candidiasis?

Candida albicans

What is the usual cause of oro-labial herpes in the UK?

HSV-1

What is the characteristic discharge of vulvovaginal candidiasis?

Off-white, curdy discharge

What is the median recurrence rate for genital herpes after a symptomatic first episode?

0.34 recurrences/month

What is the incubation period for genital herpes?

2 days to 2 weeks

What is the characteristic of local symptoms in genital herpes?

Painful ulceration, dysuria, vaginal or urethral discharge

What percentage of untreated cases can occur many years after initial infection?

One third

What is a common complication of congenital syphilis that occurs within two years of birth?

Hepatosplenomegaly

What is the recommended treatment for adults with syphilis?

All of the above

What is a risk factor for HIV transmission?

Mucosal damage

What is a common opportunistic infection in people with HIV?

All of the above

What is a characteristic of congenital syphilis that occurs after two years of birth?

All of the above

What is a recommended treatment for congenital syphilis in children?

Benzyl penicillin sodium 60–90mg/kg daily IV

What is a systemic presentation of HIV?

Tuberculosis

What is a skin condition associated with HIV?

All of the above

What is a complaint presented by the 27-year-old IT specialist in the clinical scenario?

Penile discharge and dysuria

What is the primary purpose of a physical examination in Case 1?

To examine the genital area for signs of inflammation, discharge, or ulcers

What is the main objective of laboratory tests in Case 1?

To identify the causative organism and guide treatment

Why is serological testing ordered in some cases?

To screen for other sexually transmitted infections

What is the likely diagnosis based on the patient's presentation and laboratory findings?

Gonorrhea

What is the first-line treatment for gonorrhea in Case 1?

IM Ceftriaxone 1g single dose

What is the importance of partner notification and treatment in Case 1?

To prevent further transmission of the infection

Why is education and counselling crucial in Case 1?

To educate the patient on safe sexual practices and reduce the risk of reinfection

What is the purpose of a follow-up visit in Case 1?

To monitor the patient's response to treatment

What is the prognosis for gonorrhea with appropriate antibiotic treatment and patient compliance?

Generally favourable

What can occur if the patient fails to adhere to treatment or continues high-risk behaviour?

The patient will be at risk of developing complications such as pelvic inflammatory disease

Test your knowledge on urethritis and cervicitis, including causes such as Chlamydia trachomatis, Gonorrhoea, and Non-Gonococcal Urethritis (NGU). Learn about the prevalence of different microorganisms and their effects on the body.

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