Gonococcal Infections and Antigenic Variation
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Questions and Answers

What is the characteristic finding in sterile pyuria?

  • Pus cells in urine without bacteriuria (correct)
  • Urine cultures showing viral growth
  • Urine cultures showing fungal growth
  • Presence of bacteria in urine
  • What is the most common cause of Non-Gonococcal Urethritis?

  • Ureaplasma urealyticum
  • Chlamydia trachomatis (correct)
  • E. coli
  • Mycoplasma genetalium
  • What is the morphology of Neisseria gonorrhoeae?

  • Gram-negative bacilli
  • Gram-negative diplococci (correct)
  • Gram-positive bacilli
  • Gram-positive cocci
  • What is a characteristic of Gonococcal Urethritis?

    <p>Profuse discharge and pus</p> Signup and view all the answers

    In what way are Neisseria gonorrhoeae arranged in pus cells?

    <p>Intracellular and extracellular</p> Signup and view all the answers

    What is the incubation period of Gonococcal Urethritis?

    <p>Short</p> Signup and view all the answers

    What is the primary manifestation of Gonococcal urethritis?

    <p>Discharge and dysuria</p> Signup and view all the answers

    Which of the following is a virulence factor of N. gonorrhea?

    <p>Pili (fimbriae)</p> Signup and view all the answers

    What is the mode of transmission of Gonorrhea?

    <p>Sexual contact</p> Signup and view all the answers

    What is the name of the disease caused by N. gonorrhea?

    <p>Gonorrhea</p> Signup and view all the answers

    What is the specific type of urethritis caused by N. gonorrhea?

    <p>Gonococcal urethritis</p> Signup and view all the answers

    What is the term used to describe the infection of the endocervix?

    <p>Cervicitis</p> Signup and view all the answers

    What is a possible complication of gonococcal infections in women?

    <p>Salpingitis and infertility</p> Signup and view all the answers

    How is ophthalmia neonatorum typically transmitted?

    <p>From mother to newborn during labor</p> Signup and view all the answers

    What type of infection can affect young girls due to contaminated toilets?

    <p>Gonococcal vulvo-vaginitis</p> Signup and view all the answers

    What is the term used to describe the presence of gonococci in the blood?

    <p>Gonococcal bacteremia</p> Signup and view all the answers

    Study Notes

    Gonococcal Infections

    • Gonococcal infections affect the endocervix first, leading to cervicitis and urethritis with mucopurulent discharge.
    • Complications of gonococcal infections include salpingitis and infertility.

    Non-Venereal Infections

    • Gonococcal bacteremia can occur.
    • Ophthalmia neonatorum is an eye infection of newborns transmitted from the mother during labor.
    • Gonococcal vulvo-vaginitis can affect young girls due to contaminated toilets.

    Antigenic Variation and Virulence Factors

    • Antigenic variation occurs in Gonococci.
    • Virulence factors include pili (fimbriae) and IgA protease.

    Diseases Caused by N. Gonorrhea

    • Gonorrhea is a disease caused by N. gonorrhea.
    • Gonococcal urethritis is a specific urethritis, a sexually transmitted disease that affects both males and females, manifesting with discharge and dysuria.

    Urethritis

    • Urethritis is defined as inflammation of the urethra, accompanied by dysuria, frequency, urgency, and itching.
    • Classification of urethritis includes gonococcal urethritis (specific) and non-gonococcal urethritis (non-specific).

    Causes of Urethritis

    • Gonococcal urethritis is caused by N. gonorrhea.
    • Non-gonococcal urethritis is caused by:
      • Chlamydia trachomatis
      • Mycoplasma genitalium
      • Ureaplasma urealyticum
      • E. coli
      • Acinetobacter

    Characteristics of Urethritis

    • Gonococcal urethritis has a short incubation period, sudden onset, and profuse discharge with pus.
    • Non-gonococcal urethritis has a long incubation period, gradual onset, and little discharge with pus.
    • Specimens of gonococcal urethritis contain gonococci, while those of non-gonococcal urethritis do not.

    Morphology of Neisseria Gonorrhoeae

    • Neisseria gonorrhoeae are Gram-negative diplococci, arranged in pairs with a kidney-shaped appearance.
    • They are present intracellular and extracellular in pus cells.

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    Description

    This quiz covers the symptoms, complications, and transmission of gonococcal infections, including cervicitis, urethritis, and ophthalmia neonatorum.

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