Gonococcal Infections and Antigenic Variation

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16 Questions

What is the characteristic finding in sterile pyuria?

Pus cells in urine without bacteriuria

What is the most common cause of Non-Gonococcal Urethritis?

Chlamydia trachomatis

What is the morphology of Neisseria gonorrhoeae?

Gram-negative diplococci

What is a characteristic of Gonococcal Urethritis?

Profuse discharge and pus

In what way are Neisseria gonorrhoeae arranged in pus cells?

Intracellular and extracellular

What is the incubation period of Gonococcal Urethritis?

Short

What is the primary manifestation of Gonococcal urethritis?

Discharge and dysuria

Which of the following is a virulence factor of N. gonorrhea?

Pili (fimbriae)

What is the mode of transmission of Gonorrhea?

Sexual contact

What is the name of the disease caused by N. gonorrhea?

Gonorrhea

What is the specific type of urethritis caused by N. gonorrhea?

Gonococcal urethritis

What is the term used to describe the infection of the endocervix?

Cervicitis

What is a possible complication of gonococcal infections in women?

Salpingitis and infertility

How is ophthalmia neonatorum typically transmitted?

From mother to newborn during labor

What type of infection can affect young girls due to contaminated toilets?

Gonococcal vulvo-vaginitis

What is the term used to describe the presence of gonococci in the blood?

Gonococcal bacteremia

Study Notes

Gonococcal Infections

  • Gonococcal infections affect the endocervix first, leading to cervicitis and urethritis with mucopurulent discharge.
  • Complications of gonococcal infections include salpingitis and infertility.

Non-Venereal Infections

  • Gonococcal bacteremia can occur.
  • Ophthalmia neonatorum is an eye infection of newborns transmitted from the mother during labor.
  • Gonococcal vulvo-vaginitis can affect young girls due to contaminated toilets.

Antigenic Variation and Virulence Factors

  • Antigenic variation occurs in Gonococci.
  • Virulence factors include pili (fimbriae) and IgA protease.

Diseases Caused by N. Gonorrhea

  • Gonorrhea is a disease caused by N. gonorrhea.
  • Gonococcal urethritis is a specific urethritis, a sexually transmitted disease that affects both males and females, manifesting with discharge and dysuria.

Urethritis

  • Urethritis is defined as inflammation of the urethra, accompanied by dysuria, frequency, urgency, and itching.
  • Classification of urethritis includes gonococcal urethritis (specific) and non-gonococcal urethritis (non-specific).

Causes of Urethritis

  • Gonococcal urethritis is caused by N. gonorrhea.
  • Non-gonococcal urethritis is caused by:
    • Chlamydia trachomatis
    • Mycoplasma genitalium
    • Ureaplasma urealyticum
    • E. coli
    • Acinetobacter

Characteristics of Urethritis

  • Gonococcal urethritis has a short incubation period, sudden onset, and profuse discharge with pus.
  • Non-gonococcal urethritis has a long incubation period, gradual onset, and little discharge with pus.
  • Specimens of gonococcal urethritis contain gonococci, while those of non-gonococcal urethritis do not.

Morphology of Neisseria Gonorrhoeae

  • Neisseria gonorrhoeae are Gram-negative diplococci, arranged in pairs with a kidney-shaped appearance.
  • They are present intracellular and extracellular in pus cells.

This quiz covers the symptoms, complications, and transmission of gonococcal infections, including cervicitis, urethritis, and ophthalmia neonatorum.

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