Uremia in End-Stage Renal Disease

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Questions and Answers

What is the primary feature of uremia in end-stage renal disease (ESRD)?

  • Abnormal glucose metabolism
  • Accumulation of urea in the blood (correct)
  • Total insulin deficiency
  • Excessive production of erythropoietin

Which of the following early symptoms is commonly associated with uremia?

  • Vomiting
  • Apathy (correct)
  • Confusion
  • Hyperkalemia

In the advanced stages of uremia, which electrolyte imbalance is typically observed?

  • Hypocalcemia
  • Hypomagnesemia
  • Hyperkalemia (correct)
  • Hyponatremia

What clinical manifestation indicates loss of functional kidney tissue in uremia?

<p>Nocturia (A)</p> Signup and view all the answers

What mechanism is primarily affected due to loss of functional kidney tissue in uremia?

<p>Fluid and acid-base regulation (D)</p> Signup and view all the answers

What is a common symptom that progresses as uremia develops?

<p>Confusion (B)</p> Signup and view all the answers

Which condition is primarily caused by the loss of functional kidney tissue in uremia?

<p>Fluid overload (A)</p> Signup and view all the answers

Which of the following indicates an early sign of uremia?

<p>Nocturia (A)</p> Signup and view all the answers

In advanced stages of uremia, what is a common fluid/electrolyte effect observed?

<p>Hyperkalemia (B)</p> Signup and view all the answers

What metabolic issue is closely associated with uremia in end-stage renal disease?

<p>Metabolic waste accumulation (A)</p> Signup and view all the answers

What complication can arise from pericarditis in the context of end-stage renal disease (ESRD)?

<p>Pericardial effusion (B)</p> Signup and view all the answers

Which factor contributes to the development of systemic hypertension in patients with ESRD?

<p>Retention of fluids (A)</p> Signup and view all the answers

What is a major risk associated with the immune system in patients suffering from end-stage renal disease?

<p>Delayed infection diagnosis (D)</p> Signup and view all the answers

What is a common hematologic complication in end-stage renal disease characterized by deficient red blood cell production?

<p>Anemia (C)</p> Signup and view all the answers

Impaired platelet function in patients with end-stage renal disease increases the risk of which of the following?

<p>Gastrointestinal bleeding (D)</p> Signup and view all the answers

What is a significant cardiovascular complication associated with end-stage renal disease (ESRD)?

<p>Accelerated atherosclerosis (A)</p> Signup and view all the answers

What is a common cause of anemia in patients with end-stage renal disease?

<p>Decreased erythropoietin production (A)</p> Signup and view all the answers

Which factor significantly contributes to the bleeding risks in ESRD patients?

<p>Impacted platelet function (B)</p> Signup and view all the answers

Which aspect of immune response is notably compromised in patients with end-stage renal disease?

<p>Impaired white blood cell function (B)</p> Signup and view all the answers

What complication associated with pericarditis may occur in end-stage renal disease due to retained toxins?

<p>Pericardial effusion (B)</p> Signup and view all the answers

Flashcards

Uremia Definition

The clinical condition caused by waste buildup in the blood due to failing kidneys.

Early Uremia Symptoms

Initial signs include nausea, lack of interest, weakness, and tiredness.

Progressive Uremia Symptoms

Advanced uremia symptoms involve vomiting, increased weakness, lethargy, and confusion.

Kidney Function in Uremia

Failing kidneys disrupt the body's ability to control fluids, electrolytes, and balance acids and bases.

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Early Kidney Impairment

Damage causes protein and blood in urine, frequent nighttime urination, and large amounts of urine.

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Uremia definition

Clinical syndrome of waste buildup in blood, caused by kidney failure, leading to fluid/electrolyte problems and metabolic waste.

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Early Uremia symptoms

Initial signs include nausea, apathy, weakness, and fatigue.

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Kidney function in Uremia

Failing kidneys disrupt fluid, electrolyte, and acid-base balance.

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Advanced Uremia symptoms

Progressive symptoms include vomiting, weakness, lethargy, and confusion.

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Early kidney impairment signs

Protein/blood in urine, frequent night urination, and larger-than-normal urine output.

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ESRD Accelerated Atherosclerosis

A major cause of death in patients with End-Stage Renal Disease (ESRD), often linked to high blood pressure, high cholesterol, and high blood sugar.

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ESRD High Blood Pressure

High blood pressure in ESRD is due to excess fluid, activated renin-angiotensin system, and constricted blood vessels.

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ESRD Anemia Cause

Anemia, a condition of low red blood cells, in ESRD results from reduced erythropoietin, toxins, shortened red blood cell lifespan, and nutritional issues.

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ESRD Infection Risk

ESRD increases infection risks due to impaired white blood cell function, reduced immune response, and trouble recognising infections.

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ESRD Bleeding Risk

ESRD patients have a higher risk of bleeding from the stomach or nose due to problems with blood clotting.

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ESRD Atherosclerosis

A major cause of death in people with end-stage kidney disease, often linked to high blood pressure, high cholesterol, and high blood sugar.

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ESRD Hypertension Cause

High blood pressure in ESRD is caused by extra fluid, an overactive hormone system, and narrowed blood vessels.

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ESRD Anemia

Low red blood cell count in ESRD, often caused by reduced erythropoietin and other factors.

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ESRD Infection Risk

Increased risk of infections due to weakened immune system function in ESRD.

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ESRD Bleeding Risk

Higher risk of bleeding (stomach/nose) due to blood clotting issues in ESRD.

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