BC Oxidative Phosphorylation
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Questions and Answers

Which molecules are energy-rich and involved in oxidative phosphorylation?

  • NADH and FADH2 (correct)
  • Acetyl coenzyme A
  • Pyruvate
  • NAD+ and FAD

    • What is the process called when ATP is made using the proton gradient generated by the electron transport chain?

  • Substrate level phosphorylation
  • Chemiosmosis (correct)
  • Citric acid cycle
  • Glycolysis

    • What is the role of NADH and FADH2 in cellular respiration?

  • They generate carbon dioxide
  • They convert glucose into pyruvate
  • They deliver electrons to the electron transport chain (correct)
  • They produce ATP directly

    • Where does oxidative phosphorylation occur in the cell?

    <p>Inside the mitochondria</p> Signup and view all the answers

    What is the main function of the electron transport chain?

    <p>To transfer electrons in a series of redox reactions</p> Signup and view all the answers

    What molecules do NADH and FADH2 turn back into during the delivery of electrons in cellular respiration?

    <p>NAD+ and FAD</p> Signup and view all the answers

    Which of the following is the terminal electron acceptor in the electron transport pathway?

    <p>Oxygen</p> Signup and view all the answers

    Which complex in the electron transport chain transfers electrons from FADH2 to Coenzyme Q?

    <p>Complex II</p> Signup and view all the answers

    What is the function of ATP synthase in oxidative phosphorylation?

    <p>Synthesizes ATP using the proton gradient</p> Signup and view all the answers

    What is the role of Coenzyme Q in electron transport?

    <p>Transfers electrons from NADH to Coenzyme Q</p> Signup and view all the answers

    What powers the ATP synthase in oxidative phosphorylation?

    <p>Proton gradient</p> Signup and view all the answers

    Which of the following conditions favors increased activity of the electron transport chain and oxidative phosphorylation?

    <p>All of the above</p> Signup and view all the answers

    Which of the following would be the effect of cyanide poisoning on the electron transport chain and the proton gradient across the inner mitochondrial membrane?

    <p>The electron transport chain would stop, and the gradient would decrease</p> Signup and view all the answers

    How would DNP affect the amount of ATP produced in cellular respiration?

    <p>It would decrease ATP production, but could also cause dangerously high body temperature</p> Signup and view all the answers

    Which metabolic change would be expected in a patient exposed to a toxic compound that increases the permeability of mitochondrial membranes to protons?

    <p>Increased ATP synthase activity</p> Signup and view all the answers

    What effect does cyanide poisoning have on the electron transport chain?

    <p>It stops the electron transport chain</p> Signup and view all the answers

    What effect does DNP have on the inner mitochondrial membrane?

    <p>It increases the permeability of the membrane to protons</p> Signup and view all the answers

    Why is DNP no longer on the market as a weight-loss drug?

    <p>It caused dangerously high body temperature</p> Signup and view all the answers

    Which of the following is true about glucose degradation under aerobic conditions?

    <p>Oxygen is the final electron acceptor</p> Signup and view all the answers

    Which of the following happens when ADP levels rise and the demand for ATP synthesis increases?

    <p>Oxygen consumption will increase</p> Signup and view all the answers

    What is the effect of cyanide on ATP production during respiration?

    <p>Cyanide inhibits the transfer of electrons to the final acceptor in the electron transport chain</p> Signup and view all the answers

    What is the net movement of a negative charge when ATP is transported out of the mitochondria?

    <p>Positive charge going out</p> Signup and view all the answers

    What is the P/O (Phosphate/Oxygen) Ratio in the electron transport chain?

    <p>10/4</p> Signup and view all the answers

    Which shuttle system is commonly encountered in glycolysis?

    <p>Glycerophosphate shuttle</p> Signup and view all the answers

    Which shuttle system employs an intermediate of glycolysis rather than the TCA cycle?

    <p>Glycerol phosphate shuttle</p> Signup and view all the answers

    Which of the following directly provides the energy needed to form ATP in the mitochondrion?

    <p>An electrochemical proton gradient</p> Signup and view all the answers

    During electron transport, protons are pumped out of the mitochondrion at each of the major sites except for:

    <p>Complex II</p> Signup and view all the answers

    Human produce a natural uncoupling protein that can uncouple the proton gradient from ATP synthesis. Under which of the following conditions, you think that body produces this protein?

    <p>During physical exercise</p> Signup and view all the answers

    Which of the following drugs would be most likely to prevent cavities caused by S. mutans?

    <p>A drug that inhibits the formation of a proton gradient across the cell membrane</p> Signup and view all the answers

    The enzyme isocitrate dehydrogenase (IDH) catalyzes the conversion of isocitrate to α-ketoglutarate (step 3). IDH is allosterically activated by ADP at high concentrations. Which of the following best describes how this interaction helps regulate the Krebs cycle?

    <p>Low levels of ADP stimulate the Krebs cycle, leading to the production of excess ATP that is stored for later use</p> Signup and view all the answers

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