Electron Transport Chain and Oxidative Phosphorylation
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Questions and Answers

What is the primary function of the electron transport chain?

  • To metabolize energy-rich molecules to form CO2 and H2O
  • To oxidize NADH and FADH2 (correct)
  • To synthesize ATP from ADP and Pi
  • To reduce coenzymes NAD+ and FAD to form NADH and FADH2
  • What is the net result of oxidative phosphorylation?

  • The synthesis of ATP from ADP and Pi (correct)
  • The metabolism of energy-rich molecules to form CO2 and H2O
  • The reduction of coenzymes NAD+ and FAD
  • The production of NADH and FADH2
  • What is the role of NADH and FADH2 in the electron transport chain?

  • To metabolize energy-rich molecules to form CO2 and H2O
  • To donate electrons to the electron transport chain (correct)
  • To receive electrons from the electron transport chain
  • To synthesize ATP from ADP and Pi
  • What is the byproduct of the metabolism of energy-rich molecules?

    <p>CO2 and H2O</p> Signup and view all the answers

    What is the location of the enzymes responsible for electron transport and oxidative phosphorylation?

    <p>In the mitochondria</p> Signup and view all the answers

    What is the term for the process by which ATP is synthesized from ADP and Pi?

    <p>Oxidative phosphorylation</p> Signup and view all the answers

    What is the energy-rich molecule that can donate a pair of electrons to the electron transport chain?

    <p>NADH</p> Signup and view all the answers

    What is the outcome of the electron transport chain?

    <p>The release of energy used for ATP synthesis</p> Signup and view all the answers

    What is the role of cytochromes in the electron transport chain?

    <p>They accept electrons and are reduced from Fe3+ to Fe2+</p> Signup and view all the answers

    Which complex in the electron transport chain does not produce ATP?

    <p>Complex II</p> Signup and view all the answers

    What is the result of the electrochemical gradient across the inner mitochondrial membrane?

    <p>An efflux of H+ out of the mitochondrial matrix</p> Signup and view all the answers

    What is the purpose of the proton gradient in the electron transport chain?

    <p>To produce a proton motive force for ATP synthesis</p> Signup and view all the answers

    What is the byproduct of the electron transport chain that accumulates in the intermembrane space?

    <p>H+</p> Signup and view all the answers

    What is the chemical gradient generated across the inner mitochondrial membrane?

    <p>A lower pH outside the mitochondrial membrane</p> Signup and view all the answers

    What is the electron transport chain located in?

    <p>Inner mitochondrial membrane</p> Signup and view all the answers

    What is the purpose of the ATP synthase complex?

    <p>To synthesize ATP through oxidative phosphorylation</p> Signup and view all the answers

    What are the two components of the electrochemical gradient?

    <p>Electrical gradient and chemical gradient</p> Signup and view all the answers

    Study Notes

    Electron Transport Chain (ETC) and Oxidative Phosphorylation

    • Mitochondria contain the enzymes responsible for electron transport and oxidative phosphorylation.
    • Energy-rich molecules are metabolized to form CO2 and H2O, producing metabolic intermediates that donate electrons to specific coenzymes (NAD+ and FAD) to form energy-rich reduced coenzymes (NADH and FADH2).

    Electron Transport Chain

    • Electron transport chain (ETC) or respiratory chain (RC) oxidizes NADH and FADH2, releasing energy used for ATP synthesis through oxidative phosphorylation.
    • The ETC consists of four electron transport complexes in the inner mitochondrial membrane:
      • Complex I: NADH-CoQ reductase (produces ATP)
      • Complex II: Succinate CoQ reductase (no ATP produced)
      • Complex III: CoQ- Cytochrome C reductase (produces ATP)
      • Complex IV: Cytochrome C oxidase (produces ATP)

    Cytochromes

    • Cytochromes are proteins with bound heme, each with a different reduction potential.
    • The iron atoms in cytochromes are in Fe3+, reduced to Fe2+ when accepting electrons, and reoxidized to Fe3+ when passing electrons to the next component.

    Mechanism of Oxidative Phosphorylation

    • During the ETC, H+ are released into the intermembrane space, creating an electrochemical gradient across the inner mitochondrial membrane.
    • The electrochemical gradient consists of:
      • Electrical gradient (more positive charges outside the membrane)
      • Chemical gradient (pH gradient, with lower pH outside the membrane)
    • This H+ gradient (Proton Motif Force) is used by ATP synthase complex to make ATP via oxidative phosphorylation.

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    Description

    This quiz covers the electron transport chain and oxidative phosphorylation, including the role of mitochondria, energy-rich molecules, and electron donation.

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