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Unveiling the Mysteries of Mycobacterium bovis
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Unveiling the Mysteries of Mycobacterium bovis

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Questions and Answers

What is the specificity of the skin testing (SICCT) for TB?

  • 96.5%
  • 90%
  • 98%
  • 99.98% (correct)
  • What is the sensitivity of the skin testing (SICCT) for TB?

  • 90%
  • 50-80% (correct)
  • 96.5%
  • 65%
  • What is the specificity of the INF gamma tests for TB?

  • 96.5% (correct)
  • 99.98%
  • 90%
  • 98%
  • What is the sensitivity of the INF gamma testing for TB?

    <p>90%</p> Signup and view all the answers

    What is the specificity of the antibody test for TB testing?

    <p>98%</p> Signup and view all the answers

    What is the sensitivity of the antibody test for TB testing?

    <p>65%</p> Signup and view all the answers

    Approximately what percentage of skin test reactors have no visible lesions at post-mortem inspection?

    <p>60%</p> Signup and view all the answers

    What is the protective effect of the BCG vaccine in cattle?

    <p>It has a protective effect</p> Signup and view all the answers

    What is the purpose of wildlife proofing in biosecurity?

    <p>Prevent infection via wildlife route</p> Signup and view all the answers

    Which bacterial infection primarily affects cattle and is also zoonotic?

    <p>Mycobacterium bovis (M.bovis)</p> Signup and view all the answers

    When did the prevalence of M.bovis infection in the national cattle herd start to increase?

    <p>In the 1980s</p> Signup and view all the answers

    What is the average cost of a herd TB breakdown estimated to be?

    <p>£30,000</p> Signup and view all the answers

    What is the term used to describe the strategy to eradicate bovine tuberculosis (bTB) over a 25-year period?

    <p>The Eradication Strategy</p> Signup and view all the answers

    How many management zones are there in the bovine tuberculosis (bTB) eradication strategy?

    <p>3</p> Signup and view all the answers

    What is the term used to describe testing in the area around a herd that has had a bovine tuberculosis (bTB) breakdown?

    <p>Contiguous testing</p> Signup and view all the answers

    What is one of the biosecurity measures recommended to prevent bovine tuberculosis (bTB) transmission?

    <p>Risk-based trading</p> Signup and view all the answers

    What is the primary cause of TB in people?

    <p>Other strains of mycobacteria, not M.bovis</p> Signup and view all the answers

    How many cattle were culled last year due to bTB?

    <p>Around 30,000</p> Signup and view all the answers

    What is the estimated cost of a herd TB breakdown?

    <p>£34,000</p> Signup and view all the answers

    How much of the cost of a herd TB breakdown is borne by the government?

    <p>£20,000</p> Signup and view all the answers

    How much of the cost of a herd TB breakdown is borne by the farmer?

    <p>£14,000</p> Signup and view all the answers

    How much is estimated to have cost the tax payer in the last 10 years due to bTB?

    <p>£500 million</p> Signup and view all the answers

    When did the prevalence of M.bovis infection in the national cattle herd start to increase?

    <p>Mid 80s</p> Signup and view all the answers

    What are some strategies that were focused on in the 2018 review of financial penalties for overdue tests?

    <ul> <li>Focus on biosecurity and increased industry ownership</li> <li>Strategies to increase test sensitivity</li> <li>Research into cattle vaccines and tests (DIVA/bulk milk tests)</li> <li>Genetic resistance in cattle</li> <li>Risk based trading – microchips/mandatory post movement testing/reduction in compensation paid to farmers</li> </ul> Signup and view all the answers

    What are some strategies that were focused on in the 2020 response to financial penalties for overdue tests?

    <ul> <li>Increase test sensitivity/movement restrictions</li> <li>Accelerate work on bTB cattle vaccine</li> <li>Phase out intensive badger culling and increase vaccination</li> <li>Incentivizing uptake on effective biosecurity</li> </ul> Signup and view all the answers

    What is the process for skin testing (SICCT)?

    <ul> <li>2 injections (avian and bovine tuberculin)</li> <li>Clear, inconclusive, reactor</li> <li>Standard/severe interpretation</li> <li>Specificity = 99.98%</li> <li>Sensitivity = 50-80%</li> <li>Far more likely to get false negatives than false positives</li> </ul> Signup and view all the answers

    What is the process for blood testing?

    <ul> <li>IFN gamma testing used in addition to skin testing in some breakdown herds</li> <li>Specificity = 96.5%</li> <li>Sensitivity = 90%</li> <li>More likely to get false positives than false negatives</li> <li>Antibody test occasionally used as a third line test</li> <li>Specificity = 98%</li> <li>Sensitivity = 65%</li> </ul> Signup and view all the answers

    What is the purpose of post-mortem inspection?

    <ul> <li>All cattle are inspected, but reactors/cattle from restricted herds have more detailed inspection</li> <li>Approx. 60% of skin test reactors have no visible lesions at PM – due to insensitivity of this as a diagnostic technique</li> </ul> Signup and view all the answers

    What are the challenges related to testing for bovine tuberculosis (bTB)?

    <ul> <li>Frequency and sensitivity</li> </ul> Signup and view all the answers

    What are the challenges related to vaccinating badgers for bovine tuberculosis (bTB)?

    <ul> <li>Badgers and cattle</li> </ul> Signup and view all the answers

    What are some biosecurity measures recommended to prevent bovine tuberculosis (bTB) transmission?

    <ul> <li>Cattle movements</li> <li>Risk based trading</li> </ul> Signup and view all the answers

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