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What is the typical duration of a cephalosporin regimen?
What is the typical duration of a cephalosporin regimen?
What is the priority nursing intervention for a patient with a draining wound?
What is the priority nursing intervention for a patient with a draining wound?
Why should a patient taking cephalosporins ingest buttermilk or yogurt?
Why should a patient taking cephalosporins ingest buttermilk or yogurt?
What should a patient report to their healthcare provider when taking cephalosporins?
What should a patient report to their healthcare provider when taking cephalosporins?
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What is the importance of completing the full course of cephalosporin therapy?
What is the importance of completing the full course of cephalosporin therapy?
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Why should a patient take cephalosporins with food?
Why should a patient take cephalosporins with food?
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What is the mechanism of action of cephalosporins?
What is the mechanism of action of cephalosporins?
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What is a common mechanism of resistance to cephalosporins?
What is a common mechanism of resistance to cephalosporins?
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What is a potential adverse effect of cephalosporin therapy?
What is a potential adverse effect of cephalosporin therapy?
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What is the importance of antibiotic sensitivity testing?
What is the importance of antibiotic sensitivity testing?
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What is the priority nursing intervention for a patient taking a cephalosporin?
What is the priority nursing intervention for a patient taking a cephalosporin?
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What is the primary purpose of a Culture and Sensitivity (C&S) test?
What is the primary purpose of a Culture and Sensitivity (C&S) test?
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How should IV cephalosporins be administered to prevent phlebitis?
How should IV cephalosporins be administered to prevent phlebitis?
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What is the mechanism of action of Penicillin?
What is the mechanism of action of Penicillin?
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What is the characteristic of a narrow-spectrum antibiotic?
What is the characteristic of a narrow-spectrum antibiotic?
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What is the purpose of teaching the patient to use buttermilk, yogurt, acidophilus milk, or probiotics?
What is the purpose of teaching the patient to use buttermilk, yogurt, acidophilus milk, or probiotics?
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What is a potential consequence of using broad-spectrum antibiotics?
What is a potential consequence of using broad-spectrum antibiotics?
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What is the potential effect of cephalosporin on oral birth control?
What is the potential effect of cephalosporin on oral birth control?
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Why should the patient take the entire prescribed dose of cephalosporin?
Why should the patient take the entire prescribed dose of cephalosporin?
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What is the main difference between the generations of Cephalosporins?
What is the main difference between the generations of Cephalosporins?
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What should the nurse teach the patient to expect and report regarding yeast infection?
What should the nurse teach the patient to expect and report regarding yeast infection?
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What is a common side effect of Cephalosporins?
What is a common side effect of Cephalosporins?
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What should be assessed before administering antibiotics?
What should be assessed before administering antibiotics?
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What is the purpose of monitoring vital signs and increasing fluids in a patient taking cephalosporin?
What is the purpose of monitoring vital signs and increasing fluids in a patient taking cephalosporin?
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What is a potential consequence of antibiotic resistance?
What is a potential consequence of antibiotic resistance?
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Why should the nurse administer IV cephalosporin over 30 minutes?
Why should the nurse administer IV cephalosporin over 30 minutes?
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What should the nurse teach the patient regarding the administration of cephalosporin?
What should the nurse teach the patient regarding the administration of cephalosporin?
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What should be monitored during antibiotic therapy?
What should be monitored during antibiotic therapy?
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Why is it important to obtain a Culture and Sensitivity (C&S) test before starting antibiotic therapy?
Why is it important to obtain a Culture and Sensitivity (C&S) test before starting antibiotic therapy?
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What should the nurse evaluate to determine if the cephalosporin treatment was effective?
What should the nurse evaluate to determine if the cephalosporin treatment was effective?
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What is the main difference between bacteriostatic and bactericidal drugs?
What is the main difference between bacteriostatic and bactericidal drugs?
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What is the primary mechanism of action of penicillin?
What is the primary mechanism of action of penicillin?
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What is the consequence of antibiotic misuse?
What is the consequence of antibiotic misuse?
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What is the purpose of a culture and sensitivity test?
What is the purpose of a culture and sensitivity test?
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What is cross-resistance?
What is cross-resistance?
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What is the term for the ability of an organism to resist the effects of an antibiotic?
What is the term for the ability of an organism to resist the effects of an antibiotic?
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What is the term for the ability of an antibiotic to inhibit or kill an organism?
What is the term for the ability of an antibiotic to inhibit or kill an organism?
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What is the term for the infections acquired in healthcare settings?
What is the term for the infections acquired in healthcare settings?
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What is an example of a bacterium that has developed resistance to multiple antibiotics?
What is an example of a bacterium that has developed resistance to multiple antibiotics?
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What is the mechanism of action of cephalosporins?
What is the mechanism of action of cephalosporins?
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What is the benefit of using sulfonamides and trimethoprim in combination?
What is the benefit of using sulfonamides and trimethoprim in combination?
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What is a common indication for sulfonamide therapy?
What is a common indication for sulfonamide therapy?
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What is a potential side effect of sulfonamide therapy?
What is a potential side effect of sulfonamide therapy?
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What is a contraindication for sulfonamide therapy?
What is a contraindication for sulfonamide therapy?
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What should the nurse assess before administering sulfonamides?
What should the nurse assess before administering sulfonamides?
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What is a potential interaction between sulfonamides and warfarin?
What is a potential interaction between sulfonamides and warfarin?
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What should the nurse teach the patient to do to reduce the risk of crystalluria?
What should the nurse teach the patient to do to reduce the risk of crystalluria?
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What is a potential consequence of sulfonamide therapy?
What is a potential consequence of sulfonamide therapy?
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What is the effect of taking dairy products or antacids with sulfonamides?
What is the effect of taking dairy products or antacids with sulfonamides?
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What should the nurse administer to the patient before starting sulfonamide therapy?
What should the nurse administer to the patient before starting sulfonamide therapy?
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What should the nurse monitor in a patient taking sulfonamides?
What should the nurse monitor in a patient taking sulfonamides?
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What is the effect of sulfonamides on the hypoglycemic effect of sulfonylureas?
What is the effect of sulfonamides on the hypoglycemic effect of sulfonylureas?
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What is the effect of sulfonamides on the anticoagulant effect of warfarin?
What is the effect of sulfonamides on the anticoagulant effect of warfarin?
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Why should patients taking sulfonamides increase their fluid intake?
Why should patients taking sulfonamides increase their fluid intake?
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What is the type of effect of combining two medications, such as trimethoprim and sulfamethoxazole, in co-trimoxazole?
What is the type of effect of combining two medications, such as trimethoprim and sulfamethoxazole, in co-trimoxazole?
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What is the consequence of not taking sulfonamides with antacids?
What is the consequence of not taking sulfonamides with antacids?
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Why should patients avoid taking antacids with sulfonamides?
Why should patients avoid taking antacids with sulfonamides?
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What is the effect of sulfonamides on the body's ability to excrete the medication?
What is the effect of sulfonamides on the body's ability to excrete the medication?
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What is the importance of fluid intake in patients taking sulfonamides?
What is the importance of fluid intake in patients taking sulfonamides?
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What is the type of interaction between sulfonamides and sulfonylureas?
What is the type of interaction between sulfonamides and sulfonylureas?
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What is the importance of monitoring vital signs and increasing fluids in a patient taking sulfonamides?
What is the importance of monitoring vital signs and increasing fluids in a patient taking sulfonamides?
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Why should a patient taking sulfonamides avoid taking antacids?
Why should a patient taking sulfonamides avoid taking antacids?
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What is the purpose of monitoring for bleeding and bruising in a patient taking sulfonamides?
What is the purpose of monitoring for bleeding and bruising in a patient taking sulfonamides?
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Why is it important to teach patients to increase fluid intake when taking sulfonamides?
Why is it important to teach patients to increase fluid intake when taking sulfonamides?
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What is the importance of teaching patients to wear sunglasses and sunblock when taking sulfonamides?
What is the importance of teaching patients to wear sunglasses and sunblock when taking sulfonamides?
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What is the purpose of monitoring renal function in a patient taking sulfonamides?
What is the purpose of monitoring renal function in a patient taking sulfonamides?
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Why should a patient taking sulfonamides avoid taking dairy products or antacids?
Why should a patient taking sulfonamides avoid taking dairy products or antacids?
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What is the purpose of monitoring for rash and superinfection in a patient taking sulfonamides?
What is the purpose of monitoring for rash and superinfection in a patient taking sulfonamides?
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Why should a patient taking sulfonamides take the medication on an empty stomach?
Why should a patient taking sulfonamides take the medication on an empty stomach?
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What is the purpose of teaching patients to report bruising or bleeding when taking sulfonamides?
What is the purpose of teaching patients to report bruising or bleeding when taking sulfonamides?
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Study Notes
Monitoring and Teaching
- Monitor for signs and symptoms of allergic reaction, superinfection, and organ toxicity
- Monitor vital signs and increase fluids to prevent dehydration
- Teach patients to take the entire prescribed dose, and to report signs of superinfection (yeast infection)
- Teach patients to use buttermilk, yogurt, acidophilus milk, or probiotics to maintain GI flora
- Teach patients to recognize signs and symptoms of allergy
Antibiotics Overview
- Antibiotics can be bacteriostatic (inhibit growth) or bactericidal (kill bacteria)
- Mechanisms of action include:
- Inhibition of bacterial cell wall synthesis
- Alteration of membrane permeability
- Inhibition of protein synthesis
- Inhibition of synthesis of bacterial RNA and DNA
- Interference with metabolism within the cell
Penicillin and Cephalosporins
- Penicillin:
- Narrow-spectrum and broad-spectrum types
- Action: inhibit bacterial cell wall synthesis
- Side effects: GI distress, hypersensitivity, bleeding, superinfection
- Contraindications: allergy to penicillin or cephalosporin, severe kidney disease
- Cephalosporins:
- Generations: first to fifth
- Use: bacterial infections
- Side effects: GI upset, dizziness, headache, superinfection, bleeding, allergic reaction
- Contraindications: severe kidney disease, penicillin or cephalosporin allergy
Nursing Process
- Assessment: assess for allergies, renal and liver function, review lab results and I & O
- Nursing interventions:
- Obtain C&S before giving first dose
- Administer antibiotics over 30-45 minutes
- Monitor vital signs and I & O
Practice Questions
- Priority nursing intervention for a patient with a draining wound is to obtain a culture and antibiotic sensitivity testing of infectious organism (C&S)
- When teaching a patient about cephalosporin therapy, inform them to report signs of superinfection, such as mouth ulcers or discharge from the anal or genital area
Uses of Sulfonamides
- Used in synergistic effect to delay bacterial resistance
- Used to treat urinary infections and MRSA
- Alternative therapy for patients allergic to penicillin
Routes of Administration
- Oral
- IV
- Topical
- Ophthalmic
Side Effects/Adverse Reactions
- GI distress
- Stomatitis
- Photosensitivity
- Hypoglycemia
- Blood dyscrasias (RBC's, WBC's, platelets)
- Crystalluria leading to renal failure
- Stevens-Johnson syndrome
Contraindications
- Renal or liver disease
- Anemia
- Caution in older adults and diabetes
Interactions
- Increases bleeding with warfarin
- Increases effect of hypoglycemics
- Increases digoxin level
Assessment
- Vital signs
- Renal function (urine output/labs)
- Medical history/medication history
- Allergies
- CBC (baseline)
Nursing Interventions
- Obtain C&S
- Administer with full glass of water
- Increase fluid intake to at least 2000 mL/day
- Monitor I&O, VS, and CBC
- Monitor for bleeding, CBC, and renal function
- Monitor for rash and superinfection
- Avoid during third trimester
- Best given on an empty stomach
Teaching
- Increase fluids to several quarts a day
- Do not take antacids with medication
- Warn patient if allergic to other sulfa drugs
- Teach to minimize side effects
- Teach to report adverse reactions (bruising or bleeding)
- Wear sunglasses and sunblock when outdoors
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Description
This quiz covers the importance of monitoring patients undergoing antibiotic treatment, recognizing signs and symptoms of allergic reactions, and teaching patients to maintain good health practices. It also provides an overview of antibiotics.