Biology: Cells, pH Balance and Conversions

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Questions and Answers

How many liters are equivalent to 4,800 gigaliters?

  • 4.8 x 10^12 (correct)
  • 4.8 x 10^9
  • 4.8 x 10^6
  • 4.8 x 10^15

Which enzyme catalyzes the conversion of carbonic acid into water and carbon dioxide?

  • Protease
  • Catalase
  • Carbonic anhydrase (correct)
  • Amylase

Which condition is commonly associated with respiratory alkalosis?

  • High altitudes (correct)
  • Normal altitudes
  • Low altitudes
  • Extreme changes in altitude

A patient presents with lethargy, hypotension, tachycardia, dry mucous membranes, decreased skin turgor, and the following ABG results: pH 7.55, PaCO2 45 mmHg, HCO3 34mEq/L. What acid-base disorder is the most likely diagnosis?

<p>Metabolic alkalosis (B)</p> Signup and view all the answers

What effect does an increase in hydrogen ions (H+) have on pH?

<p>Decrease pH (A)</p> Signup and view all the answers

Which type of solution allows a red blood cell to maintain its original shape and volume?

<p>Saline water (C)</p> Signup and view all the answers

What best describes a hypotonic solution?

<p>A solution with a lower solute concentration than inside the cell, causing the cell to swell. (A)</p> Signup and view all the answers

What is the pH of blood?

<p>Basic (B)</p> Signup and view all the answers

What happens to a red blood cell when it is placed in a hypertonic solution?

<p>It shrinks and may crenate (A)</p> Signup and view all the answers

Which of the following organ system pairings correctly matches the system with its primary function?

<p>Nervous and endocrine systems: rapid short-term communication and slow long-term communication (A)</p> Signup and view all the answers

What is a normal pH range for human blood?

<p>7.35-7.45 (C)</p> Signup and view all the answers

Which of the following organ system pairs and their function are correctly matched?

<p>Cardiovascular and respiratory systems: transport oxygen and nutrients to the cell, and remove carbon dioxide and waste products. (D)</p> Signup and view all the answers

What is the pH of blood in cases of acidosis?

<p>Less than 7.35 (A)</p> Signup and view all the answers

Carbon dioxide and water can be combined by carbonic anhydrase to create what?

<p>Carbonic acids (B)</p> Signup and view all the answers

How many grams are equivalent to 5 Mg?

<p>5x10^6 grams (D)</p> Signup and view all the answers

How many millimeters are equivalent to 3.1 Gm?

<p>3.1x 10^12 mm (C)</p> Signup and view all the answers

Which of the following is NOT a function of the kidneys?

<p>Production of digestive enzymes (A)</p> Signup and view all the answers

Which of the following is an example of a homeostatic process in the human body?

<p>Sweating to cool down the body on a hot day (A)</p> Signup and view all the answers

Which organ is primarily responsible for regulating blood glucose levels?

<p>Pancreas (B)</p> Signup and view all the answers

What is the primary difference between 'function' and 'process' in physiological terms?

<p>Function explains <em>why</em> and process explains <em>how</em> (D)</p> Signup and view all the answers

What is a placebo?

<p>A substance or treatment that has no therapeutic effect, but may still have a psychological benefit. (D)</p> Signup and view all the answers

How many kilograms are equivalent to 6 µg?

<p>6x 10^-9 kg (A)</p> Signup and view all the answers

How many kilometers are equivalent to 2.4 nm?

<p>2.4x 10^-12 km (C)</p> Signup and view all the answers

Which level of organization is the heart considered to be?

<p>Organ (D)</p> Signup and view all the answers

A 70-year-old man with severe COPD is admitted with increasing dyspnea, confusion, and drowsiness. His ABG shows: pH 7.28, PaCO2 65 mmHg, HCO3 30 mEq/L, and PaO2 55 mmHg. What is the primary compensatory mechanism for this disease?

<p>Kidney - Secretion of H+, reabsorption of HCO3- (C)</p> Signup and view all the answers

The sodium-potassium pump is an example of what type of transport?

<p>Active transport (D)</p> Signup and view all the answers

Which statement best describes facilitated diffusion?

<p>It uses protein channels to move molecules down their concentration gradient. (D)</p> Signup and view all the answers

Which ion is usually found in higher concentrations outside the cell?

<p>Sodium (Na+) (A)</p> Signup and view all the answers

What best describes aquaporins?

<p>Water channels that facilitate osmosis (A)</p> Signup and view all the answers

Which of the following factors can affect the rate of facilitated diffusion through a cell membrane??

<p>All of the choices (D)</p> Signup and view all the answers

The process by which cells engulf large liquid particles, such as bacteria or cell debris, through membrane invagination and vesicle formation is called:

<p>Pinocytosis (A)</p> Signup and view all the answers

What is the primary function of the sodium-potassium pump in maintaining membrane potential?

<p>It pumps potassium ions (K+) into the cell and sodium ions (Na+) out of the cell. (B)</p> Signup and view all the answers

What is the main difference between facilitated diffusion and simple diffusion?

<p>Facilitated diffusion involves the use of carrier proteins or channel proteins, while simple diffusion does not. (A)</p> Signup and view all the answers

What is the movement of water across a selectively permeable membrane from an area of higher water concentration to an area of lower water concentration called?

<p>Osmosis (D)</p> Signup and view all the answers

Which layer of the skin contains blood vessels, nerve endings, and hair follicles?

<p>Dermis (A)</p> Signup and view all the answers

Which of the following is NOT a function of the skin?

<p>Synthesis of Vitamin C (C)</p> Signup and view all the answers

Which type of skin cancer is the most aggressive and has the highest potential for metastasis?

<p>Melanoma (B)</p> Signup and view all the answers

Which layer of the skin is responsible for the production of new skin cells and is the primary target for chemotherapy?

<p>Stratum basale (C)</p> Signup and view all the answers

What is the function of Langerhans cells in the skin's immune system?

<p>Phagocytosis of pathogens (C)</p> Signup and view all the answers

If the Rate of Diffusion and Surface Area remained constant, what would happen to the concentration gradient if the membrane permeability decreased?

<p>Increase (A)</p> Signup and view all the answers

Which of the following best describes a primary function of the integumentary system?

<p>Protection against UV (D)</p> Signup and view all the answers

Which layer of the skin is primarily responsible for its strength and elasticity?

<p>Dermis (C)</p> Signup and view all the answers

Which structure in the skin is responsible for the sensation of touch?

<p>Meissner's corpuscles (C)</p> Signup and view all the answers

The Surface Area, Concentration, and Lipid Solubility remained constant. If the Molecular Size increases, what would happen to the Rate of Diffusion?

<p>Decrease (D)</p> Signup and view all the answers

A health care provider plans to give a Coumadin injection to a patient in order to thin their blood. Which type of injection would be given?

<p>Subcutaneous (B)</p> Signup and view all the answers

In a scenario where a patient presents with hypercalcemia, which of the following endocrine pathologies should be primarily investigated, considering the multifaceted interplay of calcium homeostasis?

<p>Primary hyperparathyroidism, focusing on potential parathyroid adenoma inducing excessive PTH secretion despite normal calcium feedback mechanisms. (C)</p> Signup and view all the answers

Given the intricacies of renal physiology, which of the following accurately maps the sequential flow of filtrate through the nephron's complex architecture, accounting for variable segment permeabilities and solute concentrations?

<p>Bowman's capsule → Proximal convoluted tubule → Loop of Henle → Distal convoluted tubule → Collecting duct, with each segment exerting distinct regulatory influences on filtrate composition. (A)</p> Signup and view all the answers

Considering the loop of Henle's pivotal role in renal concentration, how does its countercurrent multiplication system finely tune urine osmolality, while adapting to varying hydration states and hormonal signals?

<p>By actively transporting NaCl from the ascending limb, increasing medullary osmolality, which drives water reabsorption from the collecting duct under ADH influence. (A)</p> Signup and view all the answers

Given glucagon's crucial regulatory role, which of the following complex mechanisms most accurately describes its integrated action in elevating blood glucose, with considerations for enzymatic pathways and tissue-specific responses?

<p>Glucagon stimulates glycogenolysis and gluconeogenesis in the liver, while inhibiting glycolysis and glycogen synthesis, leading to hepatic glucose release. (D)</p> Signup and view all the answers

Considering the multifaceted effects of insulin, which of the following statements focusing on its physiological impact is NOT a characteristic effect, incorporating detailed knowledge of metabolic pathways and cellular mechanisms?

<p>Insulin increases blood glucose levels by promoting gluconeogenesis and glycogenolysis, ensuring availability of glucose during fasting periods. (B)</p> Signup and view all the answers

In a patient presenting with untreated Addison's disease, which constellation of laboratory findings is most likely given the disease's impact on adrenal hormone production and its downstream effects on electrolyte balance and hormonal feedback loops?

<p>High serum ACTH and low cortisol levels, reflecting the primary adrenal insufficiency and absence of negative feedback on ACTH secretion. (A)</p> Signup and view all the answers

Which complex condition arises from an excess of growth hormone (GH) in adults, leading to a cascade of anatomical deformities and metabolic disturbances while considering the varying sensitivity of tissues to GH?

<p>Acromegaly, characterized by enlarged bones in the hands, feet, and face due to GH-mediated stimulation of IGF-1 production. (D)</p> Signup and view all the answers

Considering the dynamic regulation of hormone synthesis and secretion, what sophisticated feedback mechanism most accurately governs hormone levels in the endocrine system, accounting for receptor sensitivity, signal transduction pathways, and hierarchical control loops?

<p>Negative feedback, where increased hormone levels inhibit further release, maintaining homeostasis by reducing stimulatory signals. (A)</p> Signup and view all the answers

In the complex process of glomerular filtration, which is the primary biophysical force that drives the movement of fluid and solutes across the glomerular capillaries into Bowman's capsule, taking into account Starling forces and membrane permeability?

<p>Hydrostatic pressure in the glomerular capillaries, exceeding the combined oncotic pressure and Bowman's capsule pressure. (A)</p> Signup and view all the answers

Regarding parathyroid hormone (PTH), how does it * orchestrate* calcium homeostasis through multifaceted interactions among bone, kidney, and intestine, with specific attention to cellular mechanisms and hormonal feedback loops?

<p>PTH increases calcium release from bones by stimulating osteoclast activity, enhances renal calcium reabsorption, and indirectly promotes intestinal calcium absorption by stimulating vitamin D activation. (D)</p> Signup and view all the answers

When blood calcium levels reach critical high concentration thresholds, which hormone responds with intricate regulatory mechanisms that involve diverse target tissues and cellular processes?

<p>Calcitonin, which promotes calcium deposition in bones by inhibiting osteoclast activity and enhances renal calcium excretion. (B)</p> Signup and view all the answers

Given the intricate regulation of erythropoiesis, how does erythropoietin (EPO) coordinate red blood cell production in response to varying oxygen tensions, with considerations for signaling pathways, cellular differentiation, and feedback mechanisms?

<p>EPO stimulates erythroid progenitor cells in the bone marrow to proliferate and differentiate into mature erythrocytes, increasing red blood cell mass. (A)</p> Signup and view all the answers

Considering the adrenal cortex's distinct zones and their highly specialized secretory products, what specific hormone is synthesized exclusively in the zona glomerulosa, and how does this spatial compartmentalization ensure precise regulation of electrolyte balance and blood pressure?

<p>Aldosterone, which promotes sodium reabsorption and potassium excretion in the kidneys. (C)</p> Signup and view all the answers

Within the context of rigor mortis, what fundamental biochemical process is primarily disrupted at the molecular level, influencing muscle contraction and relaxation?

<p>The lack of ATP after death prevents the detachment of myosin from actin, causing sustained muscle contraction. (A)</p> Signup and view all the answers

Considering the filtration process at the glomerulus, which precise pressure gradient critically determines net filtration, accounting for hydrostatic and oncotic forces in the glomerulus and Bowman's capsule?

<p>The hydrostatic pressure in the glomerular capillaries minus the sum of the hydrostatic pressure in the Bowman's capsule and the osmotic pressure of the glomerulus. (B)</p> Signup and view all the answers

Which of the subsequent statements concerning insulin and diabetes is NOT accurate, when taking into account nuanced understanding of the disease's pathophysiology?

<p>All of the following are true (A)</p> Signup and view all the answers

What is the best description of aquaporins with specific regard to cellular physiology, thermodynamics, and membrane dynamics?

<p>Water channels that facilitate osmosis (D)</p> Signup and view all the answers

Which of the following is NOT a classic function of cortisol?

<p>All of the above are functions of cortisol (E)</p> Signup and view all the answers

If a patient is suffering from hyperaldosteronism, which of the following results would be least expected?

<p>Hyperaldosteronism - Hyperkalemia on serum electrolytes (C)</p> Signup and view all the answers

Which of the subsequent pairs for endocrine disorder and diagnostic lab test is always correct?

<p>All of the above are true (A)</p> Signup and view all the answers

What is the primary function of Atrial Natriuretic Peptide(ANP)?

<p>ANP (D)</p> Signup and view all the answers

Which hormone levels would be expected in primary hyperthyroidism?

<p>Low TSH, High T3/T4 (D)</p> Signup and view all the answers

Which hormone's release is inhibited by somatostatin?

<p>Growth hormone (C)</p> Signup and view all the answers

What main condition do hypercalcemia patients suffer from?

<p>Hyperparathyroidism (C)</p> Signup and view all the answers

What is the accurate sequential flow of filtrate through the nephron?

<p>Bowman's capsule 'Proximal convoluted tubule 'Loop of Henle ' Distal convoluted tubule' Collecting duct (C)</p> Signup and view all the answers

How can the Loop of Henle facilitate the countercurrent multiplication system of the kidney?

<p>Two of the choices (C)</p> Signup and view all the answers

What best describes the action of the vital Glucagon?

<p>It raises blood glucose levels by promoting glycogen breakdown and glucose release by the liver. (D)</p> Signup and view all the answers

When reviewing which of the following statements about the physiological effects of insulin, which statement is NOT true?

<p>Insulin increases blood glucose levels by promoting gluconeogenesis and glycogenolysis. (B)</p> Signup and view all the answers

What lab values would likely show in an untreated Addison's patient, considering that Addison's is an adrenal insufficiency?

<p>High serum ACTH and low cortisol levels (B)</p> Signup and view all the answers

Which condition is best characterized by an excess of GH in adults, leading to enlarged bones in the hands, feet, and face?

<p>Acromegaly (C)</p> Signup and view all the answers

Which feedback mechanism typifies how hormone levels regulate in the endocrine system?

<p>Negative feedback (A)</p> Signup and view all the answers

What is the major driving force of glomerular filtration?

<p>Hydrostatic pressure in the glomerular capillaries (C)</p> Signup and view all the answers

What best describes the action of parathyroid hormone (PTH) on bone metabolism?

<p>PTH increases calcium release from bones by stimulating osteoclast activity. (C)</p> Signup and view all the answers

What hormone is responsible for lowering blood calcium levels when they are high?

<p>Calcitonin (A)</p> Signup and view all the answers

Which of these is not the role of erythropoietin (EPO)?

<p>E. None of the above (A)</p> Signup and view all the answers

In Myasthenia Gravis, there is a breakdown in the regular communication between nerves and muscles. Which antibodies are most commonly associated with Myasthenia Gravis?

<p>Anti-acetylcholine receptor antibodies (A)</p> Signup and view all the answers

Which substance is specifically regulated for reabsorption in the Distal Convoluted Tubule (DCT)?

<p>Sodium ions (D)</p> Signup and view all the answers

Numerous factors can influence the efficiency and effectiveness of synaptic transmission at the neuromuscular junction. Which scenario describes an alteration that would compromise synaptic transmission at the neuromuscular junction?

<p>An increase in the synthesis and release of acetylcholinesterase, which rapidly break down the acetylcholine, into the synaptic cleft (D)</p> Signup and view all the answers

Which of the following is INCORRECTLY matched with its function?

<p>E. Sarcomere - The basic unit of a neuron (C)</p> Signup and view all the answers

What feature is contributed that allows the heart to function?

<p>The presence of intercalated disks for electrical coupling (B)</p> Signup and view all the answers

Knowing that a motor unit is composed of a motor neuron and the skeletal muscle fibers innervated by that motor neuron, what best describes a motor unit?

<p>A collection of muscle fibers innervated by a single motor neuron, functioning as a single unit. (C)</p> Signup and view all the answers

Which of the following scenarios would result when the membrane permeability decreases but the Rate of Diffusion and Surface Area remain constant?

<p>The concentration gradient across the membrane will increase. (D)</p> Signup and view all the answers

Which scenario correctly integrates knowledge of diffusion dynamics, considering that Surface Area, Concentration, and Lipid Solubility remain constant?

<p>An increase in Molecular Size will cause a decrease to the Rate of Diffusion. (B)</p> Signup and view all the answers

Select the incorrect association regarding skin structures and sensory function:

<p>Meissner's corpuscles: Sense fine touch and adapt slowly to sustained stimuli. (D)</p> Signup and view all the answers

If the health care provider gave a subcutaneous injection, which layer of the skin would the injection be administered to?

<p>Hypodermis. (C)</p> Signup and view all the answers

Which of the following options accurately describe muscle contraction, clarifying the role of ATP in the process?

<p>ATP binding to myosin causes conformational changes in myosin, reducing its affinity for actin and promoting detachment. (C)</p> Signup and view all the answers

Which of the following options best describes the functional organization of skeletal muscle components, from largest to smallest?

<p>Muscle &gt; Fascicles &gt; Muscle fibers &gt; Myofibrils (A)</p> Signup and view all the answers

How does hydrostatic pressure affect glomerular filtration?

<p>It favors filtration by forcing fluid from the glomerular capillaries into Bowman's capsule. (D)</p> Signup and view all the answers

What is the function of T-tubules in regards to muscle fiber contraction?

<p>To conduct electrical impulses into the muscle fiber. (C)</p> Signup and view all the answers

In the loop of Henle, what specific structure facilitates countercurrent multiplication within the kidney to finely tune urine osmolality by responding to variations in hydration status and hormonal signals?

<p>The ascending limb, which actively transports ions out of the filtrate. (A)</p> Signup and view all the answers

Which option accurately combines an endocrine disorder and a mismatched diagnostic lab test?

<p>Hyperaldosteronism - Hyperkalemia on serum electrolytes (D)</p> Signup and view all the answers

Considering the effects of Atrial Natriuretic Peptide (ANP), which of the following statements accurately describes its primary function?

<p>Decreasing the absorption of sodium by the kidneys, thereby reducing blood volume. (D)</p> Signup and view all the answers

What hormone is responsible for the homeostasis of the body?

<p>Aldosterone. (C)</p> Signup and view all the answers

What lab results would you expect for high thyroid levels, along with primary hyperthyroidism?

<p>Low TSH, High T3/T4. (A)</p> Signup and view all the answers

Which hormone's release is inhibited by somatostatin, an action integral to the regulation of various physiological processes?

<p>Growth hormone. (D)</p> Signup and view all the answers

Which condition is most closely associated with hypercalcemia, reflecting an underlying disruption in calcium homeostasis?

<p>Hyperparathyroidism. (C)</p> Signup and view all the answers

What is the accurate sequential flow of filtrate in the nephron, highlighting the structural organization critical for renal function?

<p>Bowman's capsule -&gt; Proximal convoluted tubule -&gt; Loop of Henle -&gt; Distal convoluted tubule -&gt; Collecting duct (C)</p> Signup and view all the answers

How does the Loop of Henle facilitate the countercurrent multiplication system of the kidney?

<p>By actively transporting sodium and chloride ions out of the ascending limb, increasing the osmolarity of the surrounding medullary fluid. (A)</p> Signup and view all the answers

Which of the following statements best describes the action of glucagon?

<p>It raises blood glucose levels by promoting glycogen breakdown and glucose release by the liver. (A)</p> Signup and view all the answers

Which of the following statements about the physiological effects of insulin is NOT true?

<p>Insulin increases blood glucose levels by promoting gluconeogenesis and glycogenolysis. (C)</p> Signup and view all the answers

A patient with untreated primary Addison's disease would likely exhibit which of the following lab findings, indicative of adrenal insufficiency?

<p>High serum ACTH and low cortisol levels. (D)</p> Signup and view all the answers

Which feedback mechanism typically regulates hormone levels in the endocrine system, ensuring proper physiological balance?

<p>Negative feedback. (B)</p> Signup and view all the answers

What is the major driving force of glomerular filtration, essential for the kidney's function to filter blood?

<p>Hydrostatic pressure in the glomerular capillaries. (C)</p> Signup and view all the answers

Which of the following best describes the action of parathyroid hormone (PTH) on bone metabolism?

<p>PTH increases calcium release from bones by stimulating osteoclast activity. (C)</p> Signup and view all the answers

Which hormone is responsible for lowering blood calcium levels when they are excessively high, thus preventing hypercalcemia?

<p>Calcitonin. (D)</p> Signup and view all the answers

Which of these choices is not a role of erythropoietin (EPO) on hematopoiesis and oxygen homeostasis?

<p>Suppressing erythropoiesis in response to increasing serum oxygen levels (D)</p> Signup and view all the answers

What is the primary disruption at the molecular level within the context of rigor mortis, given its influence on muscle contraction and relaxation?

<p>Depletion of ATP, preventing the detachment of myosin from actin, resulting in sustained muscle contraction. (C)</p> Signup and view all the answers

Considering the filtration process at the glomerulus, identify the precise pressure gradient that critically determines net filtration:

<p>The hydrostatic pressure in the glomerular capillaries minus the sum of the hydrostatic pressure in Bowman's capsule and the osmotic pressure of the glomerulus. (A)</p> Signup and view all the answers

During an autopsy, a pathologist is explaining rigor mortis to medical students. Which of the following statements best elucidates the molecular mechanism underlying the rigor mortis process?

<p>The absence of ATP after death prevents the detachment of myosin from actin, causing sustained muscle fiber contraction. (A)</p> Signup and view all the answers

Given that Myasthenia Gravis disrupts communication between nerves and muscles, which antibodies are most often implicated?

<p>Anti-acetylcholine receptor antibodies. (C)</p> Signup and view all the answers

Which intervention related to synaptic transmission may likely occur at the neuromuscular junction?

<p>A decrease in the synthesis and release of acetylcholinesterase, which rapidly break down the acetylcholine, into the synaptic cleft. (A)</p> Signup and view all the answers

Which of the following pairs is INCORRECTLY matched, demonstrating a misunderstanding of basic physiology?

<p>Sarcomere - The basic unit of a neuron (D)</p> Signup and view all the answers

What is the unique feature of cardiac muscle that supports its function, setting it apart from skeletal muscle?

<p>The presence of intercalated discs for electrical coupling. (A)</p> Signup and view all the answers

What is the functional definition of a motor unit?

<p>A collection of muscle fibers innervated by a single motor neuron, functioning as a single unit. (A)</p> Signup and view all the answers

What is the pressure exerted by water vapor above a liquid in a closed system?

<p>Vapor pressure. (A)</p> Signup and view all the answers

What role does calcium ion ($Ca^{2+}$) play during muscle contraction?

<p>Binds to troponin, causing a conformational change that exposes myosin-binding sites on actin. (A)</p> Signup and view all the answers

During cross-bridge cycling, explain the role of ATP in relation to myosin heads?

<p>Is required for the detachment of myosin heads from actin. (D)</p> Signup and view all the answers

Which processes does Angiotensin II play in the Renin-Angiotensin-Aldosterone System (RAAS)?

<p>It acts as a potent vasoconstrictor and stimulates the adrenal gland to release aldosterone, increasing blood pressure and blood volume. (A)</p> Signup and view all the answers

When the stimulus frequency reaches a value beyond which no further increases in force are generated by the muscle, this is a result of:

<p>Maximum tetanic tension. (D)</p> Signup and view all the answers

Which of the following is a correct statement about nephrons?

<p>Cortical nephrons make up approximately 80% of nephrons. (A)</p> Signup and view all the answers

What effect does hydrostatic pressure have on glomerular filtration?

<p>It favors filtration by pushing fluid from the glomerular capillaries into Bowman's capsule. (C)</p> Signup and view all the answers

Flashcards

What is carbonic anhydrase?

Catalyzes the conversion of carbon dioxide and water into carbonic acid.

What is respiratory alkalosis?

A condition characterized by an elevated blood pH due to excessive respiration.

What is metabolic alkalosis?

A condition characterized by an elevated blood pH due to a metabolic disturbance that causes an increase in bicarbonate.

What is a hypotonic solution?

A solution with a solute concentration lower outside the cell, leading to cell swelling.

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What happens to a red blood cell in a hypertonic solution?

Causes a red blood cell to shrink and potentially crenate.

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Muscular and skeletal system functions?

Provide structure, support, and enable movement.

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Cardiovascular and respiratory systems function?

Transports oxygen and nutrients to cells and removes carbon dioxide and waste.

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What do carbon dioxide and water create?

Weak acid formed from carbon dioxide and water in the body.

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The function of the kidneys is NOT?

The kidneys are responsible for secretion of digestive enzymes.

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An example of homeostatic process?

Cooling the body on a hot day.

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Primary function for the Pancreas?

Responsible for regulating blood glucose levels.

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What is a placebo?

Substance with no therapeutic effect, but may have psychological benefits.

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The level of organization of the heart?

Organ

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What is the compensation mechanism to this disease?

Secretion of H+, reabsorption of HCO3-

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What best describes facilitated diffusion?

It uses protein channels to move molecules down their concentration gradient.

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Best describes aquaporins?

Water channels that facilitate osmosis

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What is pinocytosis?

Engulfing large liquid particles through membrane invagination.

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Function of the sodium-potassium pump?

It pumps potassium ions (K+) into the cell and sodium ions (Na+) out of the cell.

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The difference between facilitated and simple diffusion?

Use of carrier proteins or channel proteins

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What is Osmosis?

The movement of water across a selectively permeable membrane.

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What does the Dermis contain?

Contains blood vessels, nerve endings, and hair follicles.

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The layer of skin NOT found in thin skin?

Found in thin skin.

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Whats the role of ATP during muscle contraction?

It is required for the detachment of myosin heads from actin.

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What is the structural organization of skeletal muscle?

Largest to smallest component?

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What is the role of acetylcholine in muscle contraction?

Bind to receptors on the sarcolemma to initiate contraction

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What are Anti-acetylcholine receptor antibodies?

Antibodies most commonly associated with Myasthenia Gravis?

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Which substance is specifically regulated for reabsorption in the DCT?

Na+ is specifically regulated for reabsorption

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The unique feature of cardiac muscle is?

Electrical coupling.

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Pressure gradient is critical for the process at the glomerulus?

The hydrostatic pressure in the glomerular capillaries minus the sum of the hydrostatic pressure in the Bowman's capsule and the osmotic pressure of the glomerulus.

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Best described aquaporins?

Water channels that facilitate osmosis

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Which hormone is responsible for decreasing the absorption of sodium by the kidneys?

ANP

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A correct order of the flow of filtrate trough the nephron?

Distal convoluted tubule- collecting duct

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Action of parathyroid hormone (PTH) is?

PTH increases calcium release from bones by stimulating osteoclast activity.

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Raises blood glucose levels

The action of the hormone glucagon?

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What is 4.8 x 10^12?

A conversion factor to convert gigaliters to liters.

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What is a pathological pH disease?

A pathological condition resulting from disruptions in the body's acid-base balance.

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What happens to pH in the presence of increased H+?

It decreases the overall pH level.

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What is a saline water for a red blood cell?

The concentration of solutes is equal inside and outside the cell.

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What is Blood?

Blood has a pH of 7.4.

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What happens during acidosis?

The pH of blood gets lower than 7.35.

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Which acid is created by carbon dioxide and water?

Weak acid

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Convert 5 Mg to grams?

5x10^6 grams

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Convert 3.1 Gm to mm.

3.1x 10^12

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What are aquaporins?

Water channels in cell membranes

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What symptoms indicate a respiratory disease?

Medical history; use of accessory muscles; diminished breath sounds.

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What is osmotic pressure?

The minimum pressure required to prevent the inward flow of water across a semipermeable membrane.

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Describe the role calcium ion (Ca²z) play during muscle contraction?

Does nothing during muscle contraction

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What is Maximum tetanic tension?

When the stimulus frequency reaches a value beyond which no further increases in force are generated by the muscle.

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What effect does hydrostatic pressure have on glomerular filtration?

It favors filtration by pushing fluid from the glomerular capillaries into Bowman's capsule.

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What is the function of the T-tubules in muscle fibers?

Conduct electrical impulses into the muscle fiber

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What is the function of the collecting duct in the kidney?

It reabsorbs sodium and water under the influence of aldosterone and antidiuretic hormone (ADH), respectively, regulating urine concentration and volume.

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Wave summation is achieved by what?

Increasing the stimulus frequency

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What is the primary function of the glomerulus?

The glomerular capillaries filter blood plasma, allowing water and solutes of small molecular weight to pass into the Bowman's capsule.

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How much fluid does a healthy kidney filter?

Within a 24 hour, human glomerular capillaried can filter 180 Liters

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What happens to the neurotransmitters?

An increase in the synthesis and release of acetylcholinesterase, which rapidly break down the acetylcholine, into the synaptic cleft

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What is a motor unit?

A collection of muscle fibers innervated by a single motor neuron, functioning as a single unit.

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Which of the following conditions is associated with hypercalcemia?

Hyperparathyroidism

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Which is the best description of glucagon's mechanism?

It raises blood glucose levels by promoting glycogen breakdown and glucose release by the liver.

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A patient with untreated Addison's disease would likely exhibit which of the following lab findings?

High serum ACTH and low cortisol levels

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An excess of growth hormone leads to?

Acromegaly

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What mechanism regulates hormone levels?

Negative feedback

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Which hormone lowers calcium levels?

Calcitonin

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Which hormone is released from the zona glomerulosa?

Aldosterone

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Subcutaneous injection

A health care provider administers this type of injection under the skin.

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What is a macule?

A flat, distinct, discolored area of skin

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What is a papule?

A small, raised lesion less than 1 cm in diameter.

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Sodium-potassium pump ion movement

The sodium-potassium pump moves 3 sodium ions and 2 potassium ions simultaneously.

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Rate of Diffusion when Molecular Size increases

The rate of diffusion decreases.

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Hormone inhibited by somatostatin?

Growth hormone

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Hormone levels in hyperthyroidism?

Low TSH and High T3/T4

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The sodium-potassium pump is an example of?

Active transport.

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Factors affecting facilitated diffusion

What factors affect the rate of facilitated diffusion?

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Which ion is typically found in higher concentrations outside the cell?

Sodium (Na+)

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Primary Function of the Integumentary System?

Protection against UV

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Skin layer for strength and elasticity?

Dermis

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What is the role of angiotensin II?

It acts as a potent vasoconstrictor and stimulates the adrenal gland to release aldosterone, increasing blood pressure and blood volume.

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Study Notes

  • 4,800 gigaliters is equivalent to 4.8 x 10^12 liters.
  • Carbonic anhydrase converts carbonic acid into water and carbon dioxide.
  • Respiratory alkalosis is usually triggered by high altitudes.
  • Blood pH is 7.4
  • Saline water allows a red blood cell to maintain its original shape, neither shrinking nor swelling.
  • A hypotonic solution is characterized by, the solute concentration outside the cells being lower than inside, causing the cell to swell and potentially burst.
  • When a red blood cell is placed in a hypertonic solution, it shrinks and may crenate.
  • Muscular and skeletal systems provide structure and support, enabling movement.
  • Normal pH range for human blood is 7.35-7.45.
  • Cardiovascular and respiratory systems transport oxygen and nutrients to cells while removing carbon dioxide and waste.
  • In cases of acidosis, the pH of blood is less than 7.35.
  • Carbon dioxide and water create carbonic acids which are a weak acid.
  • 5 Mg is equivalent to 5x10^6 grams.
  • 3.1 Gm is equal to 3.1x 10^12 mm.
  • Production of digestive enzymes is NOT a function of the kidneys.
  • Sweating to cool down the body on a hot day exemplifies homeostasis in the human body.
  • The pancreas is primarily responsible for regulating blood glucose levels.
  • Function explains 'why', and process explains 'how' in physiological terms.
  • A placebo has no therapeutic effect but may still have a psychological benefit.
  • 6 µg is equivalent to 6x 10^-9 kg.
  • 2.4 nm is equivalent to 2.4x 10-12 km.
  • The heart is an organ level of organization.

COPD and ABG Analysis

  • The compensation mechanism is Secretion of H+, reabsorption of HCO3- in a 70-year-old man with severe chronic obstructive pulmonary disease (COPD)
  • Active transport is exemplified by the sodium-potassium pump.
  • Facilitated diffusion employs protein channels to move molecules down their concentration gradient.
  • The ion typically found in higher concentrations outside the cell is Sodium (Na+).
  • Aquaporins are water channels that facilitate osmosis.
  • All choices can affect the rate of facilitated diffusion through a cell membrane.
  • Pinocytosis is the process where cells engulf large liquid particles, such as bacteria or cell debris, through membrane invagination and vesicle formation.
  • The primary function of the sodium-potassium pump (Na+/K+ pump) is to maintain membrane potential by pumping potassium ions (K+) into the cell and sodium ions (Na+) out of the cell.
  • Facilitated diffusion uses carrier proteins or channel proteins, while simple diffusion does not.
  • Osmosis is water movement across a selectively permeable membrane from high to low water concentration.
  • The dermis contains blood vessels, nerve endings, and hair follicles.
  • Synthesis of Vitamin C is NOT a function of the skin.
  • Melanoma is the most aggressive skin cancer with the highest potential for metastasis.
  • The stratum basale is responsible for new skin cell production and is the primary target for chemotherapy.
  • Langerhans cells in the skin's immune system function through phagocytosis of pathogens.
  • If the rate of diffusion and surface area remain constant, the concentration gradient would increase if membrane permeability decreased.
  • Protection against UV is a primary function of the integumentary system.
  • The dermis is primarily responsible for the skin's strength and elasticity.
  • Meissner's corpuscles allow the structure in the skin to be responsible for the is sensation of touch.
  • If Surface Area, Concentration, and Lipid Solubility remained constant, the molecular size increases, what would happen to the Rate of Diffusion Decrease.
  • A Coumadin injection, to thin blood, would be given subcutaneously.
  • The stratum Lucedum is NOT found in thin skin.
  • A macule is a flat, distinct, discolored area of skin.
  • A papule is a small, raised lesion less than 1 cm in diameter.
  • The sodium-potassium pump moves 3 sodium ions and 2 potassium ions simultaneously.
  • Osmotic pressure is the minimum pressure required to prevent the inward flow of water across a semipermeable membrane.
  • Calcium ion plays none of the above roles during muscle contraction.
  • ATP is required for the detachment of myosin heads from actin during muscle contraction.
  • Angiotensin II acts as a potent vasoconstrictor and stimulates the adrenal gland to release aldosterone, increasing blood pressure and blood volume in the Renin-Angiotensin-Aldosterone System (RAAS).
  • When the stimulus frequency reaches a value beyond which no further increases in force are generated by the muscle, reach its maximum tetanic tension.
  • Cortical nephrons make up approximately 80% of nephrons.
  • All of the choices are correctly matched pairs.
  • Hydrostatic pressure favors filtration by pushing fluid from glomerular capillaries into Bowman's capsule.
  • T-tubules in muscle fibers conduct electrical impulses into the muscle fiber.
  • None of the above are characteristic of muscle hypertrophy.
  • The collecting duct reabsorbs sodium and water under aldosterone and antidiuretic hormone (ADH), respectively, regulating urine concentration and volume.
  • Increasing the stimulus frequency achieves wave summation .
  • Using GFR = Pg - (Ï€ + Pbc) the following calculation would be: Hydrostatic Pressure in Glomerulus is 120 mm Hg, Glomerular Filtration Rate is 80 mm Hg, Osmotic Pressure in the Glomerulus is 30 mm Hg Osmotic Pressure in the Bowman's Capsule is 40 mm Hg will have a result of 10 mmHg
  • Glomerular hydrostatic pressure promotes filtration in the nephron.
  • The primary function of the glomerulus in the kidney is to filter blood plasma, allowing water and solutes of small molecular weight to pass into the Bowman's capsule.
  • Muscle > Fascicles > Muscle fibers > Myofibrils, is the structural organization of skeletal muscle from largest to smallest component
  • Acetylcholine binds to receptors on the sarcolemma to initiate contraction
  • Within a 24 hour period, the human glomerular capillaries can filter 180 Liters

Myasthenia Gravis

  • Anti-acetylcholine receptor antibodies are most commonly associated with Myasthenia Gravis
  • Sodium ions are specifically regulated for reabsorption in the distal convoluted tubule (DCT) of the nephron.
  • An increase in the synthesis and release of acetylcholinesterase, which rapidly breaks down the acetylcholine, into the synaptic cleft would most likely impair synaptic transmission at the neuromuscular junction.
  • Sarcomere - The basic unit of a neuron is the incorrectly matched pair.
  • The presence of intercalated disks for electrical coupling is the unique feature of cardiac muscle contribute to its function in the heart.
  • A collection of muscle fibers innervated by a single motor neuron, functioning as a single unit is the function of a motor unit .
  • The lack of ATP after death prevents the detachment of myosin from actin, causing sustained muscle contraction exemplifies a pathologist explaining the process of rigor mortis.
  • The hydrostatic pressure in the glomerular capillaries minus the sum of the hydrostatic pressure in the Bowman's capsule and the osmotic pressure of the glomerulus is the critical pressure gradient is critical for the filtration process at the glomerulus in the context of renal blood flow.
  • All of the following are true concerning the statement about insulin and diabetes is false?
  • Aquaporins are best described as water channels facilitate osmosis.
  • All of the above are functions of cortisol
  • Hyperaldosteronism - Hyperkalemia on serum electrolytes is the mismatched pair of endocrine disorder and the diagnostic lab test typically used for its diagnosis,
  • All of the above are correctly matched for the which of the following pairs of endocrine disorder and diagnostic lab test is correctly matched?
  • ANP is responsible for decreasing the absorption of sodium by the kidneys, thus influencing blood pressure and fluid balance?
  • Low TSH, High T3/T4 hormone level would be abnormally high in a patient with primary hyperthyroidism?
  • The release of Growth hormone is inhibited by somatostatin?
  • Hyperparathyroidism is associated with hypercalcemia?
  • Bowman's capsule 'Proximal convoluted tubule 'Loop of Henle ' Distal convoluted tubule' Collecting duct correctly describe the flow of filtrate through the nephron?
  • Two of the choices are the role in the countercurrent multiplication system of the kidney?
  • Glucagon raises blood glucose levels by promoting glycogen breakdown and glucose release by the liver.
  • Insulin increasing blood glucose levels by promoting gluconeogenesis and glycogenolysis is not true?
  • In a patient with untreated Addison's disease high serum ACTH and low cortisol levels will likely exhibit?
  • An excess of GH, leading to enlarged bones in the hands, feet, and face in adults is Acromegaly
  • Negative feedback typically regulates hormone levels in the endocrine system?
  • Hydrostatic pressure in the glomerular capillaries create is the primary driving force for glomerular filtration?
  • PTH increases calcium release from bones by stimulating osteoclast activity is the best action of parathyroid hormone (PTH) on bone metabolism?
  • The hormone responsible for lowering blood calcium levels when they are high is calcitonin?
  • Aldosterone is specifically secreted from the zona glomerulosa of the adrenal cortex.

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