Podcast
Questions and Answers
Which drug is metabolized through N-dealkylation?
Which drug is metabolized through N-dealkylation?
- Caffeine (correct)
- Barbiturates
- Ibuprofen
- Amphetamines
Which drug undergoes amine oxidation in its metabolism?
Which drug undergoes amine oxidation in its metabolism?
- Ethanol
- Chloral hydrate
- Clonazepam
- Epinephrine (correct)
Which of the following drugs is metabolized by S-oxidation?
Which of the following drugs is metabolized by S-oxidation?
- Nicotine
- Acetaminophen
- Chlorpromazine (correct)
- Thioridazine
Which type of reaction is involved in the metabolism of aspirin?
Which type of reaction is involved in the metabolism of aspirin?
In humans, which process significantly induces P450-mediated drug metabolism?
In humans, which process significantly induces P450-mediated drug metabolism?
What is the main function of Cytochrome P450s in xenobiotic metabolism?
What is the main function of Cytochrome P450s in xenobiotic metabolism?
Which enzyme is responsible for the addition of glucuronic acid in Phase II reactions of xenobiotic metabolism?
Which enzyme is responsible for the addition of glucuronic acid in Phase II reactions of xenobiotic metabolism?
What is the main purpose of Glutathione-S-transferases (GST) in drug metabolism?
What is the main purpose of Glutathione-S-transferases (GST) in drug metabolism?
Which enzyme is NOT involved in Phase I reactions of xenobiotic metabolism?
Which enzyme is NOT involved in Phase I reactions of xenobiotic metabolism?
What is the primary function of Alcohol Dehydrogenase in xenobiotic metabolism?
What is the primary function of Alcohol Dehydrogenase in xenobiotic metabolism?
Which enzyme category is responsible for the addition of methyl groups to xenobiotics?
Which enzyme category is responsible for the addition of methyl groups to xenobiotics?
What is the main purpose of Phase II metabolism in xenobiotics?
What is the main purpose of Phase II metabolism in xenobiotics?
Which drug metabolism reaction involves the conjugation with glutathione?
Which drug metabolism reaction involves the conjugation with glutathione?
In alcohol metabolism, what system is responsible for increased activity in chronic alcoholism?
In alcohol metabolism, what system is responsible for increased activity in chronic alcoholism?
Which type of drug metabolism reaction involves the addition of a sulfate group?
Which type of drug metabolism reaction involves the addition of a sulfate group?
What happens to xenobiotics during Phase II metabolism?
What happens to xenobiotics during Phase II metabolism?
Which reaction type involves conjugating drugs with glucuronic acid in Phase II metabolism?
Which reaction type involves conjugating drugs with glucuronic acid in Phase II metabolism?
