Unregulated Cell Growth and Cancer Mechanisms
29 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the main learning objective of the session?

  • Learning about the normal cell cycle
  • Exploring the molecular biology of cancer
  • Understanding the mechanisms leading to unregulated cell growth in cancer (correct)
  • Understanding the impact of cancer on patients

    • What is the primary characteristic of normal cell growth?

  • Tight control and maintenance of tissue number (correct)
  • Rapid and uncontrolled growth
  • Errors in signaling the end of cell division
  • Tumour formation

    • What is the defining feature of cancer cells?

  • Errors in signaling the end of cell division
  • Tight regulation of the cell cycle
  • Rapid and uncontrolled growth (correct)
  • Tumour formation

    • Which lecture would likely cover the topic of 'Molecular Biology of Cancer'?

    <p>Lecture 3: Molecular Biology of Cancer I (A)</p> Signup and view all the answers

    What does cytokinesis refer to?

    <p>The process of cell division after mitosis (D)</p> Signup and view all the answers

    What type of cells divide only when new cells are required?

    <p>Normal cells (A)</p> Signup and view all the answers

    What is the defining feature of all cancers?

    <p>Immortality of cancer cells (B)</p> Signup and view all the answers

    How many mutations are required for cancer to reach the tumour state?

    <p>Four to six mutations (D)</p> Signup and view all the answers

    What is the main difference between normal cells and cancer cells with respect to contact inhibition?

    <p>Cancer cells do not require attachment to a physical substrate for growth (B)</p> Signup and view all the answers

    Which of the following is a characteristic of cancer cells?

    <p>Exhibit reduced requirement for growth factors to sustain proliferation (D)</p> Signup and view all the answers

    What do cancer cells exhibit with respect to apoptosis?

    <p>Immortality as they do not undergo apoptosis (C)</p> Signup and view all the answers

    What distinguishes cancerous cells from normal cells?

    <p>Reduced requirement for growth factors (A)</p> Signup and view all the answers

    What is a characteristic feature of cancerous cells with respect to chromosomal aberrations?

    <p>Chromosomal aberrations, including changes in chromosome number and structure (C)</p> Signup and view all the answers

    What is the main difference between normal and cancerous cells in terms of proliferation?

    <p>Cancer cells are immortal and do not stop dividing after a predetermined number of generations (D)</p> Signup and view all the answers

    What causes deregulated cell growth in all cancers?

    <p>Constant stimulation of cell growth by overactive growth factors or their receptors (D)</p> Signup and view all the answers

    How do cancerous tissues differ from normal tissues with respect to tissue mass maintenance?

    <p>Cancerous tissues have decreased apoptosis rates compared to normal tissues (A)</p> Signup and view all the answers

    What is responsible for controlling cell divisions?

    <p>Growth factors (D)</p> Signup and view all the answers

    Which of the following is a function of growth factors?

    <p>Regulation of cell cycle progression (A)</p> Signup and view all the answers

    What effect does the withdrawal of growth factors have on cells?

    <p>Favours apoptosis (B)</p> Signup and view all the answers

    Which protein inhibits intracellular signals related to cell proliferation and cell death?

    <p>Hormone receptors (B)</p> Signup and view all the answers

    Which growth factor stimulates gene expression in monocytes, macrophages, and fibroblasts for cell repair?

    <p>Platelet-derived growth factor (PDGF) (C)</p> Signup and view all the answers

    Which growth factor is used for the treatment of anemia of renal disease?

    <p>Erythropoietin (EPO) (B)</p> Signup and view all the answers

    In cancer, what is overactive or active inappropriately?

    <p>Growth factors or their receptors (C)</p> Signup and view all the answers

    Which factor is a breast cancer prognostic marker due to its overexpression?

    <p>EGF (epidermal growth factor) (D)</p> Signup and view all the answers

    What type of growth factors stimulate tumor growth in an autocrine fashion?

    <p>IGF-1 and IGF-2 (A)</p> Signup and view all the answers

    10

    <p>Cancer cells ignore signals to enter G0 and continue proliferating. (C)</p> Signup and view all the answers

    What is the main difference between stem cells and differentiated cells?

    <p>Stem cells have unlimited capability to renew themselves. (A)</p> Signup and view all the answers

    What happens when a normal stem cell divides?

    <p>It remains a stem cell. (A)</p> Signup and view all the answers

    Why can tissue decrease its pool of replicating cells?

    <p>Due to the induction of stem cells into post-mitotic differentiation. (D)</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser