Unraveling the Mysteries of Fibronectins
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Questions and Answers

What are the functions of fibronectin domains?

  • Binding to cell surfaces only
  • Binding to heparin and fibrin only
  • Binding to heparin, fibrin, collagen, DNA, and cell surfaces (correct)
  • Binding to collagen and DNA only
  • What are fibrillinopathies?

  • Soluble forms of fibronectin found in tissue fluids
  • Insoluble forms of fibronectin organized into fibers in the extracellular matrix
  • Connective tissue disorders caused by mutations in fibrillin genes (correct)
  • Repeating motifs in fibronectin proteins
  • What is the role of integrin receptors in fibronectin fibers?

  • To cross-link fibronectin homodimers
  • To bind to distinct regions in fibronectin (correct)
  • To contain six structural regions in fibronectin proteins
  • To integrate fibronectin fibers into the extracellular matrix network
  • What are fibrillinopathies?

    <p>Connective tissue disorders resulting from mutations in fibrillin genes.</p> Signup and view all the answers

    What are the two forms of fibronectin and where are they found?

    <p>Soluble forms are found in tissue fluids, while insoluble forms are organized into fibers in the extracellular matrix.</p> Signup and view all the answers

    What are the functions of the three types of repeating motifs in fibronectin?

    <p>The three types of repeating motifs in fibronectin are organized into functional domains that bind to Heparin, Fibrin, Collagen, DNA, and cell surfaces.</p> Signup and view all the answers

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