Undesirables in Food: Toxins Overview

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Questions and Answers

Which of the following is classified as an endogenous toxin found in potatoes?

  • Theobromine
  • Caffeine
  • Triclosan
  • Solanine (correct)

Caffeine is classified as a toxin.

False (B)

What is the key effect of solanine on the human body?

Neurological impairment

Toxic residues are carried over into food from __________ that are applied to plants or animals.

<p>procedures</p> Signup and view all the answers

Cocoa powder contains what percentage of theobromine?

<p>2% (A)</p> Signup and view all the answers

Match the following foods with their toxin content:

<p>Potatoes = Solanine Black tea = Caffeine Cocoa powder = Theobromine Cola drinks = Caffeine</p> Signup and view all the answers

Energy drinks can contain up to 300 mg/L of caffeine.

<p>True (A)</p> Signup and view all the answers

What is the maximum caffeine content allowed in cola drinks per liter?

<p>200 mg/L</p> Signup and view all the answers

Which of the following statements regarding caffeine during pregnancy is true?

<p>Decaffeinated coffee is recommended for pregnant individuals. (B)</p> Signup and view all the answers

Pyrrolizidine alkaloids can appear in milk or honey if cows or bees consume unsuitable plants.

<p>True (A)</p> Signup and view all the answers

What are psoralens, and where are they commonly found?

<p>Psoralens are substances present in plants that can cause severe skin rashes, commonly found in the green leafy parts of celery.</p> Signup and view all the answers

Chocolate can cause migraines in susceptible individuals due to its content of __________.

<p>phenylethylamine</p> Signup and view all the answers

Match the following substances with their associated effects:

<p>Caffeine = Not beneficial during pregnancy Pyrrolizidine alkaloids = Can cause liver damage Psoralens = Linked to skin rashes Cyanogenic compounds = Causes chronic poisoning from cassava</p> Signup and view all the answers

Chronic cyanide poisoning can result from the ingestion of which plant?

<p>Cassava (C)</p> Signup and view all the answers

Consuming chocolate is beneficial for everyone and does not lead to headaches.

<p>False (B)</p> Signup and view all the answers

What health issues are linked to chronic cyanide poisoning from cassava in combination with vitamin B12 deficiency?

<p>A degenerative neurological condition and a form of blindness.</p> Signup and view all the answers

Which mycotoxin is recognized as a potent liver carcinogen?

<p>Aflatoxin B1 (D)</p> Signup and view all the answers

Patulin is a dangerous mycotoxin commonly found in apple juice.

<p>False (B)</p> Signup and view all the answers

What preventive measures are recommended for controlling aflatoxin production?

<p>Controlling temperature and humidity</p> Signup and view all the answers

The mycotoxin that can contaminate cereals and is associated with kidney disease in humans is called ______.

<p>ochratoxins</p> Signup and view all the answers

Which of the following statements about botulism is true?

<p>It is a bacterial food intoxication. (D)</p> Signup and view all the answers

Aflatoxins can be expected in milk if contaminated animal feedstuffs are used.

<p>True (A)</p> Signup and view all the answers

What type of climate is associated with the occurrence of ochratoxins?

<p>Warm climates</p> Signup and view all the answers

Match the following mycotoxins with their characteristics:

<p>Aflatoxins = Potent liver carcinogens Ochratoxins = Associated with kidney disease Patulin = Used in apple juice as a marker Clostridium botulinum = Causes botulism</p> Signup and view all the answers

What percentage of the total protein in soybeans is represented by lectin proteins?

<p>3% (B)</p> Signup and view all the answers

Phytoestrogens are found in high human intake levels when consuming soy-based foods.

<p>False (B)</p> Signup and view all the answers

Name one food that contains significant levels of myristicin.

<p>Nutmeg</p> Signup and view all the answers

The toxin found in puffer fish that can cause fatalities is called __________.

<p>Tetrodotoxin</p> Signup and view all the answers

Match the following toxins with their associated food sources:

<p>Tetrodotoxin = Puffer fish Scombrotoxin = Tuna Myristicin = Nutmeg Ergotism = Rye plants</p> Signup and view all the answers

What effect does consumption of contaminated tuna lead to?

<p>Severe headaches (D)</p> Signup and view all the answers

Saxitoxin can cause paralysis and is found in shellfish affected by red tide.

<p>True (A)</p> Signup and view all the answers

What is the main source of phytoestrogens in human diets?

<p>Soya (soy products)</p> Signup and view all the answers

Ergotism is characterized by intense burning pains in the __________ and __________.

<p>hands, feet</p> Signup and view all the answers

What health issues can arise from consuming mycotoxins?

<p>Intense burning pains (B)</p> Signup and view all the answers

What is the main effect of botulinum toxin once absorbed into the body?

<p>Blocks transmission of nerve impulses (B)</p> Signup and view all the answers

Consumption of food contaminated with Staphylococcus aureus toxin is usually fatal.

<p>False (B)</p> Signup and view all the answers

Name a common symptom of a food allergy.

<p>Skin reactions</p> Signup and view all the answers

Cow's milk allergy (CMA) affects up to _____ of infants.

<p>7%</p> Signup and view all the answers

Match the types of food allergens with their characteristics:

<p>Peanuts = Particular attention is given due to severity Wheat = Causes coeliac disease Eggs = Proteins like ovomucoid can produce similar symptoms to milk Soy = Does not cause cow's milk allergy</p> Signup and view all the answers

Which of the following is a suitable treatment for coeliac disease?

<p>Complete removal of gluten from the diet (D)</p> Signup and view all the answers

Cooking inactivates the toxin produced by Staphylococcus aureus.

<p>False (B)</p> Signup and view all the answers

What is the main allergenic fraction of gluten responsible for coeliac disease?

<p>Gliadin</p> Signup and view all the answers

Pesticides are considered _____ components of our diet.

<p>unavoidable</p> Signup and view all the answers

Which food product is known to be safe for coeliac sufferers?

<p>Rice (B)</p> Signup and view all the answers

What is a common source of lead contamination in food?

<p>Lead water pipes (A)</p> Signup and view all the answers

Mercury from industrial pollution can contaminate seafood.

<p>True (A)</p> Signup and view all the answers

What are the symptoms of mercury poisoning?

<p>Damage to the central nervous system</p> Signup and view all the answers

Plastics used to package food may contain ________ which can mimic female sex hormones.

<p>phthalates</p> Signup and view all the answers

Match the following contaminants with their sources:

<p>Lead = Gasoline combustion Mercury = Cereal grains dressed with antifungal compounds Dioxins = Combustion of chlorinated compounds PCBs = Industrial waste</p> Signup and view all the answers

At what level is mercury in fish considered the maximum permitted?

<p>0.5 ppm (A)</p> Signup and view all the answers

Polynuclear hydrocarbons (PAHs) are beneficial and not harmful.

<p>False (B)</p> Signup and view all the answers

What design feature can reduce harmful emissions from grilling meat?

<p>Vertical design grill</p> Signup and view all the answers

Bisphenol A (BPA) is no longer allowed in making ________.

<p>baby bottles</p> Signup and view all the answers

Which of the following is true about PCBs?

<p>They were banned due to their toxicological problems. (C)</p> Signup and view all the answers

Flashcards

Solanine

A bitter, heat-stable glycoalkaloid found in potatoes and eggplants. It can build up in potatoes exposed to sunlight, turning them green, and is concentrated just under the skin.

How does solanine affect the body?

Solanine inhibits the action of acetylcholinesterase, a crucial enzyme in the nervous system.

Caffeine and Theobromine

Stimulants found in tea, coffee, cocoa, and cola beverages.

Caffeine in Coffee

The caffeine content of roasted coffee beans is around 1-2%, varying depending on the brewing method.

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Caffeine in Black Tea

Black tea leaves contain 3-4% caffeine, resulting in approximately 50mg per cup.

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Caffeine and Theobromine in Chocolate

Cocoa powder contains 2% theobromine and 0.2% caffeine, with levels varying in different chocolate types.

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Caffeine in Cola and Energy Drinks

Cola drinks are restricted to 200mg/L of caffeine, with most containing around 65mg/L. Energy drinks often include extracts of Guarana for even higher caffeine levels, reaching 200-300mg/L.

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Caffeine's Physiological Actions

Caffeine stimulates the release of adrenaline and noradrenaline, leading to various effects on glucose, triglycerides, and cholesterol levels in the blood.

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What are Pyrrolizidine alkaloids (PAs)?

Pyrrolizidine alkaloids (PAs) are naturally occurring toxins found in certain plants, like comfrey, which can contaminate milk and honey if animals or bees ingest them. They have been linked to liver damage, especially when consumed in herbal remedies.

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What are psoralens?

Psoralens are natural substances with insecticidal properties found in plants like celery. They can cause severe skin rashes in those who work closely with them, particularly when absorbed through the skin from the plant's green parts.

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What is phenylethylamine?

Phenylethylamine is a vasopressor amine found in chocolate, cheese, and wine. It can cause migraine headaches in susceptible individuals by constricting blood vessels, potentially leading to hypertension.

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What is cyanogenesis?

Cyanogenesis is a process that releases cyanide, a toxic compound, from plants like cassava. Chronic exposure to low levels of cyanide through cassava consumption can cause severe health problems.

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How does cassava relate to cyanide poisoning?

Cassava, a starchy root vegetable, contains cyanogenic glycosides, which release cyanide when ingested. Chronic exposure to low levels of cyanide from cassava can lead to serious health issues. Two common diseases associated with cyanide exposure from cassava are degenerative neurological conditions and a form of blindness.

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What are the main toxins in legumes?

Raw legumes, such as peas, beans, peanuts, and soybeans, contain two main types of toxins: (1) lectins, which are proteins that can interfere with intestinal absorption and cause digestive problems, and (2) antinutritional factors, which can inhibit the absorption of nutrients and lead to nutrient deficiencies.

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What is a safer coffee option for pregnant women?

Decaffeinated instant coffee is a safer alternative for pregnant women compared to caffeinated coffee. While caffeine itself doesn't cause birth defects or low birth weights, its stimulant effects are not beneficial during pregnancy.

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What are endogenous toxins of plant foods?

Certain plant foods contain naturally occurring toxins, also called endogenous toxins. These substances can have adverse effects on humans and are often present in the plant's defense mechanisms against insects or other organisms.

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Aflatoxins

A group of toxins produced by the fungus Aspergillus flavus. One of the most potent liver carcinogens known, particularly dangerous in peanuts and peanut butter.

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Hepatotoxins

Aflatoxins are toxic to the liver. Long-term exposure can lead to liver damage, cancer, and hepatitis B.

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Aflatoxins in Milk

Aflatoxins can be found in milk due to contaminated animal feedstuffs.

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Aflatoxin Conversion

Aflatoxin B1 and G1 are converted into M1 by liver enzymes, appearing in milk and posing a serious problem for the dairy industry.

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Ochratoxins

A mycotoxin found in warm climates that contaminates cereals. Associated with kidney disease in humans.

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Patulin

A mycotoxin that occurs in apple juice and home-made jam, indicating the use of moldy fruit. Not considered a dangerous toxin.

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Botulism

The most feared bacterial food poisoning caused by the toxin secreted by the anaerobic bacterium Clostridium botulinum.

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Clostridium botulinum Heat Resistance

The vegetative cells of Clostridium botulinum are not particularly resistant to heat, unlike its spores.

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Lectin Proteins

Proteins found in legumes that bind to red blood cells, causing them to clump together. This action is called hemagglutination.

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Phytoestrogens

A type of toxin found in plants, specifically soybeans. They mimic the effects of estrogen in the body.

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Myristicin

A compound found in nutmeg and other spices. It can cause euphoria, hallucinations, and even nausea and delirium in large doses.

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Tetrodotoxin

A toxin found in pufferfish, specifically in the liver and ovaries. It can cause paralysis and death, even at very low doses.

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Saxitoxin

A toxin produced by red algae that can accumulate in shellfish. It causes a type of poisoning called Paralytic Shellfish Poisoning (PSP) and affects the nervous system.

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Scombrotoxin (Histamine)

A type of toxin commonly found in tuna and sardines. It is formed when the fish is not handled properly and stored at high temperatures.

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Mycotoxins

Toxins produced by certain fungi that can contaminate food. They are often highly dangerous and can cause various health issues.

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Ergotism

A disease caused by a mycotoxin called ergot, which contaminates grains like rye. It can cause severe health problems involving burning pain, loss of sensation, and mental derangement.

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Ergot

A specific form of mycotoxin that can cause ergotism.

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Cooking

The process of heating food to destroy harmful substances, such as toxins or bacteria. It is an essential part of food safety.

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Botulinum toxin

A neurotoxin produced by Clostridium botulinum bacteria, which blocks nerve impulses to muscles leading to paralysis and potentially death.

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Staphylococcus aureus food poisoning

Contamination of food with Staphylococcus aureus toxin, which is heat-resistant and causes vomiting and diarrhoea.

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Food allergy

An exaggerated immune response to a food component, leading to symptoms like skin reactions, vomiting, and breathing difficulties.

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Coeliac disease

An immune response to proteins in wheat, barley, and rye, particularly the gliadin fraction of gluten.

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Cow's milk allergy (CMA)

A food allergen found in cow's milk, affecting up to 7% of infants.

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Egg allergy

A protein found in eggs, particularly ovomucoid, which can cause allergic reactions.

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Pesticide residues

Chemicals used to control pests, which can contaminate food and pose health risks.

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Toxic metal residues

Heavy metals like lead, mercury, and cadmium, which can accumulate in food and harm human health.

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Food chemistry

The scientific study of food and its relationship to health, focusing on the chemical composition and effects on the body.

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Digestion

The process of breaking down food into smaller molecules that can be absorbed by the body. This involves mechanical and chemical processes.

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Lead in Food

Lead is a metal that can contaminate food and accumulate in our bodies over time. It's commonly found in old water pipes, leaded gasoline, and paints.

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Mercury in Seafood

Mercury, often from industrial pollution or antifungal treatments, can contaminate seafood. Once in sediment, it turns into methylmercury, a highly toxic form.

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PAHs from Cooking

PAHs, formed when food is cooked at high temperatures, are carcinogenic, meaning they can cause cancer. They are especially high in barbecued meat, where fat drips onto hot charcoal.

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Plastic Packaging Residues

Plastics used for packaging can leach chemicals into our food. Plasticizers, like phthalates, can mimic hormones and affect fertility. BPA, used in certain plastics, is banned from baby bottles.

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Dioxins in Food

Dioxins, formed during the burning of materials containing chlorine, are persistent pollutants. They build up in fatty tissues and can harm our health.

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PCBs in Food

PCBs, once used for various purposes, are now banned due to their toxic properties and persistence in the environment. They accumulate in fatty tissues, like dioxins.

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Dirt on Vegetables

The dirt on unwashed vegetables can carry bacteria and pathogens that cause foodborne illnesses.

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Contaminated Crops

Sewage sludge, when applied to crops, can introduce harmful bacteria and parasites. Fertilizers and other chemicals can also contaminate food.

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Contaminated Food Processing Water

Water used to process food, if contaminated, can introduce bacteria and other contaminants into the final product.

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Contaminated Food Processing Equipment

Equipment and utensils used in food processing, if not properly cleaned, can spread bacteria and other contaminants.

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Study Notes

Undesirables in Food

  • Four categories of undesirables exist: endogenous toxins, microbial toxins, toxic residues, and toxic contaminants.
  • Endogenous toxins are natural components of food.
  • Microbial toxins arise from contaminating molds or bacteria.
  • Toxic residues are carried over into food from procedures applied to plants or animals.
  • Toxic contaminants arise during food processing.

Endogenous Toxins of Plant Foods

  • Solanine: A bitter, heat-stable glycoalkaloid found in potatoes and eggplants. Potatoes exposed to light turn green, increasing solanine levels, primarily beneath the skin. Its presence inhibits acetylcholinesterase, a key nervous system enzyme, causing neurological impairment at high doses.
  • Caffeine and Theobromine alkaloids: Found in tea, coffee, cocoa, and cola beverages, these substances are stimulants, not toxins. They are not considered nutrients.
    • Roasted coffee beans contain 1-2% caffeine; typical beverage levels are 50-125 mg per serving.
    • Black tea contains 3-4% caffeine, usually 50 mg per serving.
    • Cocoa powder contains 2% theobromine and 0.2% caffeine.
    • Plain chocolate contains 0.5% theobromine and 0.05% caffeine; milk chocolate has 0.2% theobromine and 0.02% caffeine.
    • Cola drinks are limited to 200 mg/L caffeine; average is ~65 mg/L. "Energy drinks" can contain 200-300 mg/L caffeine (about 5 cups of coffee).
  • Pyrrolizidine alkaloids (PAs): Associated with herbal remedies. They can be found in milk or honey from cows or bees fed contaminated plants. Comfrey is a plant containing over 12 different PAs; these are linked with liver damage.
  • Psoralens: Natural insecticides found in celery and other plants. They can cause skin rashes, especially in farm workers.
  • Phenylethylamine: Found in chocolate; in susceptible people it can cause migraines due to its vasoconstricting properties.
  • Cyanogenic compounds: Present in cassava, these can cause chronic cyanide poisoning when ingested at low levels over prolonged periods; this is widespread in cassava-dependent areas. It is connected to vitamin B12 deficiency and neurodegenerative disorders.

Endogenous Toxins of Animal Foods

  • Tetrodotoxin: Present in several puffer fish organs (liver and ovaries), it's extremely poisonous, with a low lethal dose (1.5-4.0 mg); licensing of expert cooks is vital to prevent fatalities.
  • Red tide poisoning: Massive proliferation of red-pigmented dinoflagellates in coastal waters can produce toxins that accumulate in shellfish, the most potent being saxitoxin, causing paralysis.
  • Scombrotoxin (histamine): Formed in some fish (tuna and sardines) at above 10°C, it leads to headaches, palpitations, gastrointestinal, and skin issues.

Mycotoxins

  • Ergotism: A mycotoxin produced by fungi on rye; its onset can be slow but lead to significant health problems, especially if not treated immediately. Modern fungicides and inspection help reduce incidence.

  • Aflatoxins: Produced by Aspergillus flavus, these are potent liver carcinogens and hepatotoxins. Aflatoxins B1 and G1 are converted into M1 in the liver, which can contaminate milk, posing a hazard to dairy industries. Preventive measures for aflatoxin production control temperature and humidity.

  • Ochratoxins: Mycotoxins that contaminate cereals in warm climates and are linked with kidney disease.

  • Patulin: Used as a marker in apple juice for moldy fruit; found in homemade jam contaminated by molds.

Bacterial Toxins

  • Botulism: Caused by the toxin secreted by the anaerobic bacterium Clostridium botulinum, characterized by intense burning pain, paralysis, and death; canning techniques eliminate spores.
  • Staphylococcus aureus enterotoxins: Present in some foods, these are resistant to heat and digestive enzymes, leading to unpleasant but non-fatal symptoms, like stomach upset.

Allergens

  • Food components can cause allergies: Some people react badly to specific food components.
  • Allergy types: Skin reactions, vomiting, diarrhea, difficulty breathing, and anaphylaxis can all result from food allergies.
  • Important types of allergens: Cow's milk, peanuts, wheat (gluten), and eggs.
  • Coeliac disease: An allergy to wheat (gliadin fraction of gluten) that damages the small intestine. Gluten-free diet is fundamental for treatment.

Toxic Agricultural Residues

  • Pesticides: Universally dispersed in the environment; they are unavoidable in the food we eat; DDT use is greatly limited or banned.

Toxic Metal Residues

  • Lead: A metal that is ingested through contaminated soil, air(from gasoline combustion), and water; its concentration potentially increases with age.
  • Mercury: Can be found in products with antifungals, industrial pollution, and consequently in seafood. It's primarily a concern in some fish species and converts to methyl mercury in sediments, a toxic form.

Toxins from Heat Treatment

  • Polyaromatic hydrocarbons (PAHs): Formed when carbohydrates or fats are heated above 500°C, they are linked to cancer risk. Barbecued meat, improperly cooked foods and smoke are significant sources. Cooking methods designed to prevent fat dripping can help.

Packaging Residues

  • Plasticizers (especially phthalates and BPA): Chemicals added to plastics to prevent brittleness, these can mimic hormones and potentially impact fertility and other health concerns. Use of some plasticizers is restricted.

Environmental Pollutants

  • Dioxins: Produced during combustion of chlorinated materials, they accumulate in animal and human fatty tissues.
  • PCBs (polychlorinated biphenyls): Banned due to toxicity and persistence in the environment, these accumulate in animal and human fatty tissues.

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