Understanding Uniport, Cotransport, Symport, and Antiport
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Questions and Answers

What is the function of the lipid layer in the tear film?

  • Enhancing tear production
  • Stimulating blinking reflex
  • Preventing tear evaporation (correct)
  • Providing nutrients to the cornea

Which of the following is NOT a component of the lipid layer in tear film?

  • Cholesterol
  • Wax esters
  • Triacylglycerols
  • Proteins (correct)

During tear-film breakup time, the subsequent blink is stimulated by:

  • Pain sensation
  • Muscle contraction
  • Corneal dryness
  • Film stabilization (correct)

Which gland secretes Meibum, a crucial component of the tear film lipid layer?

<p>Meibomian gland (D)</p> Signup and view all the answers

The aqueous layer of tear film contains which of the following components?

<p>Dissolved salts (D)</p> Signup and view all the answers

In tear film formation, when substances are transported in opposite directions, it is an example of:

<p>Antiport (A)</p> Signup and view all the answers

What is the major component of the lipid layer of the precorneal tear film?

<p>Waxes (C)</p> Signup and view all the answers

Which of the following is derived from eicosanoic acids and includes examples like prostaglandins and leukotrienes?

<p>Eicosanoids (B)</p> Signup and view all the answers

What is the main characteristic of glycolipids?

<p>Found in nervous, ocular, and other tissues (C)</p> Signup and view all the answers

What is the basic structure that binds glycolipids?

<p>Sphingosine (D)</p> Signup and view all the answers

In which glycolipid is phosphocholine esterified to a ceramide?

<p>Sphingomyelin (A)</p> Signup and view all the answers

What is the function of lipid esters found in tear film?

<p>Help the lipids adhere to the eyelid skin and act as a barrier to the aqueous layer (A)</p> Signup and view all the answers

What is a possible cause contributing to meibomian gland dysfunction?

<p>Increased cholesterol and appearance of ceramides (D)</p> Signup and view all the answers

What is the advantage of high fluidity of the photoreceptor disc membrane?

<p>Allows for rotational and lateral movements of rhodopsin needed for phototransduction (D)</p> Signup and view all the answers

To what class of lipids does Vitamin A belong?

<p>Isoprenoid (B)</p> Signup and view all the answers

What is the role of Vitamin E in the retina?

<p>Absorbs free radicals (A)</p> Signup and view all the answers

What are the chemical forms of Vitamin A and their roles?

<p>Retinyl ester: storage; Retinol: transport; Retinal: visual transduction; Retinoic acid: synthesis (D)</p> Signup and view all the answers

What process involves the transport of 3 sodium ions out of the cell and 2 potassium ions into the cell by hydrolyzing 1 molecule of ATP?

<p>Antiport (C)</p> Signup and view all the answers

Which type of transport involves substances being transported in the same direction, such as glucose transport in kidney tubules?

<p>Symport (A)</p> Signup and view all the answers

What is the primary function of the lipid layer in tear film?

<p>To stabilize the tear film (A)</p> Signup and view all the answers

Which components are present in the anterior/superficial lipid layer of tear film?

<p>Cholesteryl esters and waxes (B)</p> Signup and view all the answers

In tear-film formation, when substances are transported simultaneously, it is an example of:

<p>Cotransport (C)</p> Signup and view all the answers

Which gland secretes Meibum, a crucial component of the tear film lipid layer?

<p>Meibomian gland (B)</p> Signup and view all the answers

What is the result of tear-film breakup time?

<p><strong>Stimulation</strong> of the next blink (B)</p> Signup and view all the answers

What is the composition of the aqueous layer in tear film?

<p><strong>Dissolved salts and proteins</strong> (B)</p> Signup and view all the answers

What is the significance of the protein to lipid ratio in a membrane?

<p>Helps gauge the role of membrane – transport, metabolism, and signal transduction (A)</p> Signup and view all the answers

What is simple diffusion and provide an example?

<p>Movement from lower to higher concentration without energy, example: movement of glucose using GLUT-1 (C)</p> Signup and view all the answers

How does facilitated transport differ from active transport?

<p>Facilitated transport occurs against the concentration gradient, while active transport occurs down the gradient (B)</p> Signup and view all the answers

What is the role of glycolipids in cell membranes?

<p>Serve as biological bridges and bonding agents in membranes (B)</p> Signup and view all the answers

Which membrane has a protein to lipid ratio of 3:1?

<p>Mitochondrial inner membrane (C)</p> Signup and view all the answers

What is the primary function of glycoproteins in cell membranes?

<p>Function as molecular bridges between cells (C)</p> Signup and view all the answers

Which type of transport is limited by the ability of proteins or enzymes to perform the task?

<p><em>Facilitated transport</em> (A)</p> Signup and view all the answers

Give an example of a process that requires enzyme catalysis for energy to operate a pump moving molecules against their concentration gradient.

<p><em>Active transport</em> (D)</p> Signup and view all the answers

What is one of the functions of lipid esters found in the tear film?

<p>Help the lipids form a film over the aqueous layer and maintain contact with it (A)</p> Signup and view all the answers

Which is a possible cause contributing to meibomian gland dysfunction?

<p>Detachment of epithelial cells from the gland blocking lipid flow to the tear film (A)</p> Signup and view all the answers

Why is high fluidity crucial for the photoreceptor disc membrane?

<p>Enables rotational and lateral movements required for phototransduction (C)</p> Signup and view all the answers

To which class of lipids does Vitamin A belong?

<p>Isoprenoid (A)</p> Signup and view all the answers

What happens in the retina in the absence of Vitamin E?

<p>Free radicals attack membrane fatty acids, breaking them into fragmentary aldehydes (D)</p> Signup and view all the answers

What is a role of retinol among the chemical forms of Vitamin A?

<p>Transport and hormonal function (C)</p> Signup and view all the answers

Which statement describes a function of Vitamin E in the retina?

<p>Absorption of free radicals (B)</p> Signup and view all the answers

What are common dietary sources of Vitamin A apart from animal sources?

<p>Carrots, sweet potatoes (D)</p> Signup and view all the answers

What is a common adverse effect of high daily intake of Vitamin A?

<p>Blurred vision (B)</p> Signup and view all the answers

Where do gangliosides mainly reside in the body?

<p>Nervous tissue (D)</p> Signup and view all the answers

What is the characteristic physical feature of Tay-Sachs disease?

<p>Accumulation of gangliosides in nerve tissues (A)</p> Signup and view all the answers

What enzyme deficiency leads to Tay-Sachs disease?

<p>Hexosaminidase A (C)</p> Signup and view all the answers

In which region of the eye is the characteristic cherry-red spot observed due to Tay-Sachs disease?

<p>Macular region (A)</p> Signup and view all the answers

What is the primary impact of ganglioside accumulation in the retina?

<p>Degeneration of ganglion cells (B)</p> Signup and view all the answers

How does Tay-Sachs disease affect the lifespan of affected individuals?

<p>Causes early childhood death (B)</p> Signup and view all the answers

What are some common symptoms experienced with high Vitamin A intake?

<p>Irritability and abdominal pain (C)</p> Signup and view all the answers

What is the main role of Chylomicra in the body?

<p>Incorporate hydrophobic lipids (D)</p> Signup and view all the answers

How is retinol conveyed from the liver to target cells?

<p>Mobilization after binding to prealbumin (B)</p> Signup and view all the answers

What happens to retinol after it enters target cells?

<p>Released and transported via a receptor protein (C)</p> Signup and view all the answers

Which proteins are involved in mobilizing retinal for transport to target cells?

<p>Prealbumin and retinol binding protein (A)</p> Signup and view all the answers

What are the three disorders of the eye caused by Vitamin A deficiency?

<p>Nyctalopia, xerophthalmia, keratomalacia (B)</p> Signup and view all the answers

What does Keratomalacia involve?

<p>Degeneration of corneal epithelium and corneal perforation (B)</p> Signup and view all the answers

Which process occurs after all-trans retinal is converted to 11-cis-retinal in the retina?

<p>Esterification and isomerization (D)</p> Signup and view all the answers

What is Xerophthalmia primarily characterized by?

<p>Dry eyes due to hardening of corneal conjunctiva (A)</p> Signup and view all the answers

Which type of lipids are found on the surface of chylomicra transport complexes?

<p>Hydrophilic lipids (D)</p> Signup and view all the answers

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