Understanding the Cytochrome P450 System Naming Convention
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Questions and Answers

What does CYP stand for in the context of the text?

  • Cytosolic Pathway
  • Cysteine Peptide
  • Cytochrome Protein
  • Cytochrome P450 (correct)
  • In the naming convention of cytochrome enzymes, what do the numbers following 'CYP' represent?

  • Reaction kinetics
  • Substrate specificity
  • Active site location
  • Cytochrome family (correct)
  • Which component of the mixed-function oxidase system is responsible for transferring an oxygen atom to the substrate RH?

  • Heme proteins
  • Cytochrome P450 oxidase enzymes (correct)
  • NADH-linked cytochrome b5
  • NADPH-dependent CYP reductase
  • What is the reducing agent needed in the oxidative process catalyzed by CYP enzymes?

    <p>NADPH</p> Signup and view all the answers

    What is the end product formed when one atom of molecular oxygen is introduced into the substrate R-H in xenobiotic metabolism?

    <p>ROH</p> Signup and view all the answers

    Study Notes

    CYP Enzymes

    • CYP stands for Cytochrome P450

    Naming Convention

    • Numbers following 'CYP' in the naming convention of cytochrome enzymes represent the family (first number), subfamily (letter), and individual enzyme (number)

    Mixed-Function Oxidase System

    • The component of the mixed-function oxidase system responsible for transferring an oxygen atom to the substrate RH is CYP enzymes

    Oxidative Process

    • The reducing agent needed in the oxidative process catalyzed by CYP enzymes is NADPH and FADH

    Xenobiotic Metabolism

    • The end product formed when one atom of molecular oxygen is introduced into the substrate R-H in xenobiotic metabolism is R-OH

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    Description

    Learn about the naming convention of the cytochrome P450 system, which includes a family designation (CYP1, CYP2, etc.), a subfamily represented by a capital letter (CYP1A, CYP2B, etc.), and a specific enzyme number (CYP1A2, CYP2C9, etc.). Explore how this naming system identifies enzymes responsible for various reactions.

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