Podcast
Questions and Answers
What does CYP stand for in the context of the text?
What does CYP stand for in the context of the text?
- Cytosolic Pathway
- Cysteine Peptide
- Cytochrome Protein
- Cytochrome P450 (correct)
In the naming convention of cytochrome enzymes, what do the numbers following 'CYP' represent?
In the naming convention of cytochrome enzymes, what do the numbers following 'CYP' represent?
- Reaction kinetics
- Substrate specificity
- Active site location
- Cytochrome family (correct)
Which component of the mixed-function oxidase system is responsible for transferring an oxygen atom to the substrate RH?
Which component of the mixed-function oxidase system is responsible for transferring an oxygen atom to the substrate RH?
- Heme proteins
- Cytochrome P450 oxidase enzymes (correct)
- NADH-linked cytochrome b5
- NADPH-dependent CYP reductase
What is the reducing agent needed in the oxidative process catalyzed by CYP enzymes?
What is the reducing agent needed in the oxidative process catalyzed by CYP enzymes?
What is the end product formed when one atom of molecular oxygen is introduced into the substrate R-H in xenobiotic metabolism?
What is the end product formed when one atom of molecular oxygen is introduced into the substrate R-H in xenobiotic metabolism?
Study Notes
CYP Enzymes
- CYP stands for Cytochrome P450
Naming Convention
- Numbers following 'CYP' in the naming convention of cytochrome enzymes represent the family (first number), subfamily (letter), and individual enzyme (number)
Mixed-Function Oxidase System
- The component of the mixed-function oxidase system responsible for transferring an oxygen atom to the substrate RH is CYP enzymes
Oxidative Process
- The reducing agent needed in the oxidative process catalyzed by CYP enzymes is NADPH and FADH
Xenobiotic Metabolism
- The end product formed when one atom of molecular oxygen is introduced into the substrate R-H in xenobiotic metabolism is R-OH
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Description
Learn about the naming convention of the cytochrome P450 system, which includes a family designation (CYP1, CYP2, etc.), a subfamily represented by a capital letter (CYP1A, CYP2B, etc.), and a specific enzyme number (CYP1A2, CYP2C9, etc.). Explore how this naming system identifies enzymes responsible for various reactions.
