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Questions and Answers
What is the primary role of the CFTR protein?
What is the primary role of the CFTR protein?
- Act as a potassium ion channel
- Act as a sodium ion channel
- Act as a calcium ion channel
- Act as a chloride ion channel (correct)
Which chromosome is the gene for the protein CFTR located on?
Which chromosome is the gene for the protein CFTR located on?
- Chromosome 5
- Chromosome 10
- Chromosome 7 (correct)
- Chromosome 13
What is the mutation known as that accounts for approximately 70% of all mutations in CFTR?
What is the mutation known as that accounts for approximately 70% of all mutations in CFTR?
- Alpha508
- Beta508
- Delta508 (correct)
- Gamma508
What type of inheritance does Cystic Fibrosis (CF) exhibit?
What type of inheritance does Cystic Fibrosis (CF) exhibit?
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How do mutations influence the function of the CFTR protein product?
How do mutations influence the function of the CFTR protein product?
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What is the specific mutation responsible for approximately 70% of all mutations in the CFTR gene?
What is the specific mutation responsible for approximately 70% of all mutations in the CFTR gene?
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How do mutations influence the function of the CFTR protein product?
How do mutations influence the function of the CFTR protein product?
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What type of inheritance does Cystic Fibrosis (CF) exhibit?
What type of inheritance does Cystic Fibrosis (CF) exhibit?
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What is the primary role of the CFTR protein?
What is the primary role of the CFTR protein?
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Why do ΔF508 homozygotes almost always have the severe classical CF?
Why do ΔF508 homozygotes almost always have the severe classical CF?
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