10 Questions
Which neurotransmitter is primarily affected in Parkinson's disease?
Dopamine
What is the mechanism of action of ropinirole in Parkinson's disease?
Dopamine receptor agonist
What is the main consequence of tetanospasmin binding to the synapse membrane?
Rigidity due to glycine release blockage
Why did Don develop a strong interest in gambling after starting ropinirole?
Dopamine receptor agonists can cause impulsive behavior
Which receptor type does not contain ion channels but may use a second messenger system to open nearby ion channels?
G-protein coupled receptors
What is the main function of the VTA in the brain?
Reward, motivation, and addiction
What is the function of monoamine oxidase inhibitors?
Preventing dopamine breakdown at synapse
Which neurotransmitter is responsible for excitotoxicity when released excessively?
Glutamate
Which type of antagonist binds to a different site than the endogenous ligand, weakening the signal output?
Noncompetitive antagonist
What class of neurotransmitters includes Glutamate, Aspartate, and Glycine?
Amino acids
Learn about the mechanism of action of tetanospasmin in causing muscle rigidity and the resulting condition of opisthotonus. Understand why proper wound cleaning is crucial in preventing tetanus. Explore how sedation can help manage the symptoms.
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