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Understanding Tetanus and Opisthotonus

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Questions and Answers

Which neurotransmitter is primarily affected in Parkinson's disease?

GABA

Acetylcholine

Serotonin

Dopamine (correct)

What is the mechanism of action of ropinirole in Parkinson's disease?

Monoamine oxidase inhibition

Dopamine receptor agonist (correct)

GABA reuptake inhibitor

Acetylcholinesterase inhibitor

What is the main consequence of tetanospasmin binding to the synapse membrane?

Rigidity due to glycine release blockage (correct)

Muscle atrophy due to decreased calcium levels

Sedation due to glutamate inhibition

Hyperactivity due to dopamine release

Why did Don develop a strong interest in gambling after starting ropinirole?

Dopamine receptor agonists can cause impulsive behavior (B) Signup and view all the answers

Which receptor type does not contain ion channels but may use a second messenger system to open nearby ion channels?

G-protein coupled receptors (A) Signup and view all the answers

What is the main function of the VTA in the brain?

Reward, motivation, and addiction (D) Signup and view all the answers

What is the function of monoamine oxidase inhibitors?

Preventing dopamine breakdown at synapse (A) Signup and view all the answers

Which neurotransmitter is responsible for excitotoxicity when released excessively?

Glutamate (D) Signup and view all the answers

Which type of antagonist binds to a different site than the endogenous ligand, weakening the signal output?

Noncompetitive antagonist (A) Signup and view all the answers

What class of neurotransmitters includes Glutamate, Aspartate, and Glycine?

Amino acids (C) Signup and view all the answers