Understanding Seizures and Their Causes
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Questions and Answers

What typically causes the first seizure in individuals over 20 years of age?

  • Genetic predisposition
  • Neurotransmitter imbalances
  • Structural changes or trauma (correct)
  • Uncontrolled electrical discharge
  • Which statement best describes unprovoked seizures?

  • They do not involve any electrical discharge.
  • They are associated with epilepsy. (correct)
  • They have a known trigger such as infection.
  • They are caused by identifiable factors.
  • What might contribute to the occurrence of seizures according to the theories on their causes?

  • Low levels of glucose in the bloodstream
  • High levels of oxygen in the brain
  • Increased blood flow to the brain
  • Neuron membrane alterations (correct)
  • What is the definition of a seizure?

    <p>An abnormal, uncontrolled electrical discharge in the brain (B)</p> Signup and view all the answers

    Which of these is a characteristic symptom of seizures?

    <p>Abrupt alteration in cerebral activity (D)</p> Signup and view all the answers

    What characterizes focal seizures without impairment of consciousness?

    <p>They may have motor, sensory, or autonomic symptoms. (D)</p> Signup and view all the answers

    Which type of seizure typically arises in the temporal lobe and involves a loss of consciousness?

    <p>Focal seizures with impairment of consciousness (C)</p> Signup and view all the answers

    What is an aura in the context of seizures?

    <p>A warning sensation or experience prior to a seizure. (B)</p> Signup and view all the answers

    What distinguishes generalized seizures from focal seizures?

    <p>Generalized seizures involve both hemispheres from the start. (B)</p> Signup and view all the answers

    What is a common characteristic of tonic-clonic seizures?

    <p>Involuntary muscle contractions and loss of consciousness. (A)</p> Signup and view all the answers

    What defines status epilepticus in terms of seizure duration?

    <p>Seizures lasting 30 minutes or more (B)</p> Signup and view all the answers

    Which of the following medications is typically used during seizure activity?

    <p>Lorazepam (C)</p> Signup and view all the answers

    What percentage of patients can stop their medications and remain seizure-free after achieving control?

    <p>60% (A)</p> Signup and view all the answers

    What is a known potential consequence of untreated status epilepticus?

    <p>Respiratory failure and death (D)</p> Signup and view all the answers

    Which treatment may be considered if pharmacological treatments with two or more drugs are not effective?

    <p>Surgery (A)</p> Signup and view all the answers

    What is a key characteristic of generalized seizures?

    <p>They involve unconsciousness. (D)</p> Signup and view all the answers

    Which type of generalized seizure is characterized by a sudden loss of muscle tone resulting in the drooping of limbs?

    <p>Atonic Seizure (A)</p> Signup and view all the answers

    What is NOT a common manifestation of absence seizures?

    <p>Rhythmic jerking movements (C)</p> Signup and view all the answers

    Which phase of a tonic-clonic seizure involves sharp muscle contractions and immediate loss of consciousness?

    <p>Tonic phase (A)</p> Signup and view all the answers

    What diagnostic test is commonly used to help identify seizure activity?

    <p>Electroencephalogram (EEG) (A)</p> Signup and view all the answers

    What may occur during the tonic phase of a tonic-clonic seizure?

    <p>Cyanosis and incontinence (C)</p> Signup and view all the answers

    What trigger is associated with myoclonic seizures?

    <p>Cerebral stimuli (C)</p> Signup and view all the answers

    Which category of generalized seizures is defined by lasting only a few seconds with no convulsions?

    <p>Absence (B)</p> Signup and view all the answers

    Flashcards

    Generalized Seizures

    Seizures that involve both hemispheres of the brain from the onset.

    Focal Seizures

    Seizures that start in one hemisphere of the brain; can be with or without impairment of consciousness.

    Focal Seizures Without Impairment

    Focal seizures that do not affect consciousness or awareness, may include motor and sensory symptoms.

    Focal Seizures With Impairment

    Focal seizures that begin in one hemisphere and may spread, causing impaired consciousness and awareness.

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    Aura

    A sensory warning sign that precedes a seizure, may include unusual sensations or emotions.

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    Seizure Protection

    Avoiding injury during seizure episodes.

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    Status Epilepticus

    Continuous seizures lasting over 30 minutes.

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    Anti-epileptic Drugs

    Medications used to control seizures based on type.

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    Prognosis for Seizure Patients

    With treatment, seizures may stop for 1/3 of patients.

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    Sudden Unexplained Death in Epilepsy (SUDEP)

    A rare complication where cause remains unknown.

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    Seizure

    An abnormal and uncontrolled electrical discharge from neurons in the cerebral cortex.

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    Causes of Seizures

    Alterations in neuron membranes, ion distribution, decreased inhibition, structural changes, or neurotransmitter imbalances.

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    Epilepsy prevalence in Canada

    1 in 100 Canadians are diagnosed with epilepsy, often with first seizure before age 20.

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    Unprovoked Seizures

    Seizures with no known cause, often classified as epilepsy.

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    Provoked Seizures

    Seizures caused by an underlying condition, such as infections or trauma.

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    Absence Seizures

    Brief disturbances in consciousness without convulsions, characterized by a blank stare and motionlessness.

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    Atonic Seizures

    Seizures leading to sudden loss of muscle tone, causing slackening of the jaw and limbs.

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    Myoclonic Seizures

    Seizures with brief involuntary muscle jerks, which may affect one or both sides of the body.

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    Tonic-Clonic Seizures

    Major motor seizures with two phases: tonic (muscle contraction) and clonic (rhythmic contractions).

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    Tonic Phase

    The first phase of a tonic-clonic seizure marked by muscle contraction and loss of consciousness.

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    Clonic Phase

    The second phase of a tonic-clonic seizure marked by rhythmic muscle contractions.

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    EEG

    A diagnostic test used to measure electrical activity in the brain, often used in seizure evaluation.

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    Study Notes

    Seizures

    • Seizures are abnormal, uncontrolled electrical discharges from a group of neurons in the cerebral cortex.
    • This leads to abrupt and temporary alterations in cerebral activity.
    • Seizures are a symptom of underlying central nervous system (CNS) dysfunction.
    • Severity and presentation vary depending on the site of the discharge in the brain.

    Theories on Causes of Seizures

    • Neuron membrane alterations
    • Imbalances in ion distribution
    • Decreased activity of inhibitory neurons
    • Structural changes
    • Neurotransmitter imbalances

    Seizures in Canada

    • Approximately 1 in 100 Canadians have epilepsy.
    • First seizures typically occur before age 20.
    • Seizures after age 20 are often due to structural changes, trauma, tumors, or stroke.

    Broad Categories of Seizures

    • Unprovoked seizures: Cause unknown, often associated with epilepsy
    • Provoked seizures: Secondary to an underlying cause such as infections (e.g., HIV, bacterial meningitis, and others), head injury, etc.

    Focal vs. Generalized Seizures

    • Focal seizures involve one hemisphere of the brain. They can be further categorized by whether or not consciousness is impaired during the seizure.
      • Focal seizures without impairment of consciousness: May be localized or widespread within the hemisphere. Characterized by no loss of consciousness or responsiveness and can have motor, sensory, or autonomic symptoms. The initial part of the seizure can be recognized as an aura.
      • Focal seizures with impairment of consciousness: Begin in one hemisphere and rapidly spread to the other, often originating in the temporal lobe. May cause loss of consciousness and awareness as well as hallucinations and illusions. These seizures may also present automatisms (e.g., repetitive movements or behaviors) and confusion, which can last after the seizure has ended (post-ictal state).
    • Generalized seizures involve both hemispheres of the brain at onset. These seizures are typically accompanied by unconsciousness and symmetrical motor activity on both sides of the body. There are six broad categories of generalized seizures.

    Types of Generalized Seizures

    • Absence seizures: Characterized by disturbances in consciousness, but no convulsions. Typically occur only in children. Manifestations include blank stares, being motionless and unresponsive, and often brief loss of contact with the environment.
    • Atonic seizures: Characterized by a sudden loss of muscle tone. Manifestations may include jaw slackening, drooping limbs, and falling to the ground.
    • Myoclonic seizures: Characterized by brief, involuntary muscle contractions. The contractions can be bilateral or confined to the face, trunk, or extremities. The seizures are often triggered by cerebral stimuli.
    • Tonic-clonic seizures: Characterized by a tonic phase (muscle contraction and extension of extremities) followed by a clonic phase (rhythmic bilateral contraction and relaxation of extremities). Unconsciousness often occurs during the tonic phase and continues until the post-ictal phase. They are typically major motor seizures and may have a vague warning sign (focal seizure) beforehand.

    Diagnostic Tests for Seizures

    • Neurological exam
    • Electroencephalogram (EEG)
    • Computed tomography (CT) scan or magnetic resonance imaging (MRI)
    • Lab tests

    Treatment for Seizures

    • Protect from injury during a seizure.
    • Reduce seizure activity through pharmacological means.
    • Medications vary depending of the type of seizure
    • Surgery may be an option if medications are not effective.
    • Neurostimulators are also used in some cases.

    Complication: Status Epilepticus

    • Prolonged seizure activity, lasting 30 minutes or more.
    • Can lead to respiratory failure and death if not treated immediately through airway maintenance and medications.
    • Identification of the underlying cause (e.g., tumors) is essential for appropriate treatment.
    • It is a medical emergency.

    Prognosis for Seizures

    • With medication treatment:
    • Seizures may be eliminated in about one-third of individuals.
    • Seizure frequency may reduce in a significant portion.
    • About sixty percent of patients who remain seizure-free can discontinue antiepileptic medication.
    • Sudden unexpected death in epilepsy (SUDEP) is a rare but significant complication with an unknown cause.

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    Week 4 Seizures F22 Student PDF

    Description

    This quiz explores the nature of seizures, their causes, and their prevalence in Canada. Delve into the differences between provoked and unprovoked seizures, and gain insights into the various factors affecting neuronal activity. Perfect for those studying neurology or related fields.

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