Podcast
Questions and Answers
What is the diameter of the spherical enveloped particle of retroviruses?
What is the diameter of the spherical enveloped particle of retroviruses?
- ~80-100nm (correct)
- ~10-20nm
- ~200-250nm
- ~50-60nm
Which proteins are derived from the pol gene in retroviruses?
Which proteins are derived from the pol gene in retroviruses?
- MA (matrix), CA (capsid), NC (nucleocapsid)
- SU (external surface protein, also called gp120) and TM (transmembrane protein, also called gp24)
- MA (matrix), CA (capsid), NC (nucleocapsid)
- PR (protease), RT (reverse transcriptase), IN (integrase) (correct)
What is the function of the gag gene in retroviruses?
What is the function of the gag gene in retroviruses?
- Encoding of envelope proteins: SU (external surface protein, also called gp120) and TM (transmembrane protein, also called gp24)
- Involvement in genome replication and integration
- Cleavage of polyprotein into mature proteins
- Production of group-specific antigen proteins: MA (matrix), CA (capsid), NC (nucleocapsid) (correct)
What is the initial step in the unique replication cycle of retroviruses?
What is the initial step in the unique replication cycle of retroviruses?
What is the role of reverse transcriptase in retroviruses?
What is the role of reverse transcriptase in retroviruses?
Where does the DNA enter after being made from the ssRNA genome by viral enzyme integrase?
Where does the DNA enter after being made from the ssRNA genome by viral enzyme integrase?
What is bound to genomic RNA by base pairing with primer binding sequences downstream of U5?
What is bound to genomic RNA by base pairing with primer binding sequences downstream of U5?
What are the two subfamilies into which retroviruses were reclassified?
What are the two subfamilies into which retroviruses were reclassified?
What is the function of Ppt in retroviruses?
What is the function of Ppt in retroviruses?
What is the main basis for the tropism of retroviruses?
What is the main basis for the tropism of retroviruses?
What is the role of ribonuclease H (RNAse H) in reverse transcription?
What is the role of ribonuclease H (RNAse H) in reverse transcription?
What facilitates the DNA polymerase activity during reverse transcription?
What facilitates the DNA polymerase activity during reverse transcription?
Which type of genome does HIV possess?
Which type of genome does HIV possess?
What causes depletion of CD4+ T cells in HIV-infected individuals?
What causes depletion of CD4+ T cells in HIV-infected individuals?
What is the main basis for the tropism of retroviruses?
What is the main basis for the tropism of retroviruses?
What is the diameter of the spherical enveloped particle of retroviruses?
What is the diameter of the spherical enveloped particle of retroviruses?
What facilitates the DNA polymerase activity during reverse transcription?
What facilitates the DNA polymerase activity during reverse transcription?
What is the role of ribonuclease H (RNAse H) in reverse transcription?
What is the role of ribonuclease H (RNAse H) in reverse transcription?
What is bound to genomic RNA by base pairing with primer binding sequences downstream of U5?
What is bound to genomic RNA by base pairing with primer binding sequences downstream of U5?
Which proteins are derived from the pol gene in retroviruses?
Which proteins are derived from the pol gene in retroviruses?
What causes depletion of CD4+ T cells in HIV-infected individuals?
What causes depletion of CD4+ T cells in HIV-infected individuals?
What is the function of Ppt in retroviruses?
What is the function of Ppt in retroviruses?
What is the function of the env gene in retroviruses?
What is the function of the env gene in retroviruses?
What is the role of the U3 region in retroviruses?
What is the role of the U3 region in retroviruses?
What is the function of the protease (PR) protein in retroviruses?
What is the function of the protease (PR) protein in retroviruses?
What is the specific cellular component bound to genomic RNA by base pairing with primer binding sequences (PBS) downstream of U5?
What is the specific cellular component bound to genomic RNA by base pairing with primer binding sequences (PBS) downstream of U5?
What is the primary function of reverse transcriptase (RT) in retroviruses?
What is the primary function of reverse transcriptase (RT) in retroviruses?
What is the role of nucleocapsid protein in retroviruses?
What is the role of nucleocapsid protein in retroviruses?
What is the function of integrase (IN) enzyme in retroviruses?
What is the function of integrase (IN) enzyme in retroviruses?
Which proteins are derived from the gag gene in retroviruses?
Which proteins are derived from the gag gene in retroviruses?