Understanding Polysaccharides and Gut Flora

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Questions and Answers

What type of linkages are found in cellulose?

  • α-1,6 linkages
  • β-1,4 linkages (correct)
  • δ-1,3 linkages
  • γ-1,5 linkages

Which polysaccharide is primarily made of fructose and is good for digestion?

  • Starch
  • Glycogen
  • Inulin (correct)
  • Cellulose

Which organism relies on symbiotic gut microflora to digest cellulose?

  • Humans
  • Most multicelled animals (correct)
  • Fish
  • Bacteria

Which transporter is responsible for transporting fructose into the cell?

<p>GLUT5 (D)</p> Signup and view all the answers

How do termites reconstitute their gut flora?

<p>By eating nestmates' feces (D)</p> Signup and view all the answers

Which is crucial for the absorption of carbohydrates at the brush border?

<p>Sodium concentration gradient (B)</p> Signup and view all the answers

What change occurs to the villi in the gut of animals during high digestion periods?

<p>They extend (C)</p> Signup and view all the answers

Where does the majority of the biotransformation of phenylephrine occur?

<p>Intestinal epithelium (A)</p> Signup and view all the answers

What happens to the absorption of monomers after digestion in the small intestine?

<p>Monomers are not absorbed at all (B)</p> Signup and view all the answers

Which of the following is NOT a carbohydrate transporter at the brush border?

<p>GLUT4 (A)</p> Signup and view all the answers

Flashcards

Cellulose

A complex carbohydrate composed of many glucose molecules linked together by β-1,4 glycosidic bonds.

Inulin

A type of polysaccharide made up of fructose molecules. It's found in some plants and is good for digestion.

Vertebrate digestion of cellulose and inulin

Most multicellular animals lack the necessary enzymes to break down cellulose and inulin.

Symbiotic gut microflora

Microorganisms living in the gut that help break down complex carbohydrates that the host's digestive system can't.

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Absorption

The process by which nutrients are absorbed from the digestive tract into the bloodstream.

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Absorption of carbohydrates at the brush border

The process by which sugars are transported across the intestinal wall.

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SGLT1

A protein that helps transport glucose and sodium into the intestinal cells.

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GLUT5

A type of protein that helps transport fructose across the intestinal wall.

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Post-absorption processing

The process by which the body breaks down and modifies absorbed molecules.

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Sulfate conjugation

A chemical process in which a sulfate group is added to a molecule.

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Study Notes

Other Polysaccharides

  • Cellulose is a poly-glucose molecule with β-1,4 linkages.
  • Inulin is a poly-fructose molecule found in some plants instead of starch. It aids digestion, promotes satiety, and is difficult for the body to break down.
  • Vertebrates lack enzymes to break down cellulose and inulin.
  • They rely on symbiotic gut microflora, a process that occurs in the large intestine, not the small intestine.
  • This results in gas production.

Symbiotic Gut Flora

  • Symbiotic protists aid termites in digesting cellulose and lignin.
  • Termites must shed their exoskeletons (moult) to grow.
  • The lining of the digestive tract is also molted during this process.
  • To replenish the gut flora, termites consume the feces of nestmates.

Absorption of Carbohydrates at the Brush Border

  • The Na+/K+ pump maintains a sodium gradient, driving sodium from the lumen into absorptive cells.
  • SGLT1 co-transports sodium and glucose into the cell.
  • Fructose enters the cell via the GLUT5 transporter, moving down its concentration gradient.
  • Glucose, galactose, and fructose are transported into interstitial fluid by facilitated diffusion, moving down their concentration gradient.
  • Other sugars follow a similar transport pathway.
  • Gut surface area can be increased by extending villi, especially during periods of high digestion, such as summer, then reduced during winter or hibernation.

Post-Absorption Processing

  • Phenylephrine is rapidly metabolized (typically by conjugation to a sulfate group) primarily in the intestinal epithelium.
  • This leaves little active phenylephrine in circulation, limiting its systemic effects.
  • The small intestine is a crucial site for absorption.

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