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Questions and Answers
NSAIDs are primarily used to relieve pain and increase inflammation.
NSAIDs are primarily used to relieve pain and increase inflammation.
False (B)
Chronic conditions like rheumatoid arthritis can be treated with NSAIDs.
Chronic conditions like rheumatoid arthritis can be treated with NSAIDs.
True (A)
Selective COX-2 inhibitors like celecoxib are a type of non-steroidal anti-inflammatory drug.
Selective COX-2 inhibitors like celecoxib are a type of non-steroidal anti-inflammatory drug.
True (A)
Common side effects of NSAIDs include dyspepsia, anxiety, and vomiting.
Common side effects of NSAIDs include dyspepsia, anxiety, and vomiting.
Prostaglandins and leukotrienes are synthesized as a result of NSAID actions.
Prostaglandins and leukotrienes are synthesized as a result of NSAID actions.
The stretching behavior exhibited by the animals is known as writhing.
The stretching behavior exhibited by the animals is known as writhing.
Acetic acid is not involved in the stimulation process described.
Acetic acid is not involved in the stimulation process described.
The stimulation process requires an irritant to be injected.
The stimulation process requires an irritant to be injected.
The characteristic behavior is unrelated to any injected substance.
The characteristic behavior is unrelated to any injected substance.
The animals display their writhing behavior without external stimulation.
The animals display their writhing behavior without external stimulation.
Writhe involves the constriction of the abdomen and the turning of the trunk.
Writhe involves the constriction of the abdomen and the turning of the trunk.
The action of writhe does not include the extension of the hind legs.
The action of writhe does not include the extension of the hind legs.
The term 'talo' refers to twisting and constriction in abdominal muscles.
The term 'talo' refers to twisting and constriction in abdominal muscles.
Twisting of the trunk is a key component of the writhe movement.
Twisting of the trunk is a key component of the writhe movement.
Writhe only involves the upper body movements.
Writhe only involves the upper body movements.
The number of writhes for each animal is counted during a time period of 30 minutes.
The number of writhes for each animal is counted during a time period of 30 minutes.
Counting of writhes begins immediately after the injection of acetic acid.
Counting of writhes begins immediately after the injection of acetic acid.
The behavior observed is described as a form of stretching.
The behavior observed is described as a form of stretching.
Acetic acid injection has no effect on the animals' behavior.
Acetic acid injection has no effect on the animals' behavior.
The writhing behavior is a common characteristic of all animal species.
The writhing behavior is a common characteristic of all animal species.
A drug with analgesic activity reduces the number of writhings in animals compared to control.
A drug with analgesic activity reduces the number of writhings in animals compared to control.
If a drug does not have analgesic activity, it will still decrease the writhing response in animals.
If a drug does not have analgesic activity, it will still decrease the writhing response in animals.
The presence of analgesic activity in a drug implies that it can inhibit writhing.
The presence of analgesic activity in a drug implies that it can inhibit writhing.
Animals receiving an analgesic drug will exhibit more writhing compared to the control group.
Animals receiving an analgesic drug will exhibit more writhing compared to the control group.
A higher number of writhings in animals indicates the effectiveness of an analgesic drug.
A higher number of writhings in animals indicates the effectiveness of an analgesic drug.
Study Notes
What are NSAIDs?
- Nonsteroidal anti-inflammatory drugs (NSAIDs) are used to reduce pain and inflammation signs
- NSAIDs are commonly used to treat long-term health problems, such as rheumatoid or osteoarthritis
- Newer NSAIDs, such as celecoxib, are known as COX-2 inhibitors or selective COX-2 NSAIDs
General Unwanted Effects of NSAIDs
- Dyspepsia, nausea and vomiting
- Acetic acid is commonly used to induce writhing in animals
- Writhing is a characteristic stretching behavior of animals; this involves constriction of the abdomen, turning of the trunk and extension of the hind legs
- Analgesic drugs reduce the number of writhes an animal performs during a certain period; typically 30 minutes beginning 5 minutes after the injection of acetic acid
Prostaglandins & Leukotrienes
- Prostaglandin and Leukotrienes synthesis is not mentioned in the text provided
- This text focuses on writhing behaviors and analgesics, which are not directly related to prostaglandin or leukotriene synthesis
- Further research is needed to understand the relationship between prostaglandin and leukotriene synthesis and the action of NSAIDs
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Description
This quiz delves into the types and effects of nonsteroidal anti-inflammatory drugs (NSAIDs), their usage in treating various conditions, and common unwanted effects. It also covers the role of analgesics in reducing pain behaviors observed in animals.
