Understanding Karyotypes and Their Applications

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What is the purpose of treating cells with colchicine in karyotype preparation?

To arrest cells at metaphase for condensed chromosome characterization

What is the purpose of arranging metaphase chromosomes in homologous pairs?

To determine the size and centromere location of chromosomes

What is the purpose of photographing stained metaphase spreads in karyotype preparation?

To document and analyze chromosome arrangements

Which stain is commonly used to prepare chromosomes for karyotyping?

Giemsa stain

Genetic linkage is the phenomenon in genes that are close together on the same chromosome tend to be transmitted ____________

together

A chromosome is a single piece of ________

DNA

Why are individual chromosomes cut and arranged in pairs in descending order during karyotype preparation?

To organize them based on size and centromere position

Different versions of the same gene are called ____________

alleles

Linked genes sit close together on a chromosome, making them likely to be inherited together. A chromosome is a single piece of ________.

DNA

During the formation of gametes, chromosomes go through a process called ____________

homologous recombination

A single chromosome can have hundreds of even thousands of ________.

genes

Most sexually reproducing organisms, like people and pigeons, have two copies of each chromosome called ____________

homologous chromosomes

Humans have 23 chromosome pairs, or 46 chromosomes in all. Homologous chromosomes have the same genes arranged in the same order, but they have slightly different ________ sequences.

DNA

During the formation of gametes (eggs and sperm in people and pigeons), chromosomes go through a process called ________.

recombination

Different versions of the same gene are called ________. Homologous chromosomes often contain different alleles.

alleles

Learn about karyotypes, the arrangement of metaphase chromosomes in homologous pairs, and their applications, including species identification, detecting chromosome abnormalities, and diagnosing diseases. Explore the preparation of karyotypes and their role in genetic analysis.

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