Understanding Inflammation: Response to Injury and Infection

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19 Questions

What are the four cardinal signs of acute inflammation listed by Celsus in the first century A.D.?

Rubor, Calor, Tumor, Dolor

What are the general components of inflammation according to the text?

Vascular reaction and Cellular reaction

What is the primary function of inflammation as mentioned in the text?

Protective response

What causes edema in inflammation according to the text?

Increased hydrostatic pressure and lowered intravascular osmotic pressure

What are some examples of potentially harmful conditions related to inflammation as mentioned in the text?

Chronic diseases like arthritis and atherosclerosis

What is the historical significance of Celsus in the context of inflammation?

Listed the four cardinal signs of acute inflammation

Which component of inflammation results from increased hydrostatic pressure and lowered intravascular osmotic pressure?

Edema

What are the stimuli that can lead to inflammation as mentioned in the text?

Infections, trauma, physical or chemical agents, foreign bodies, immune reactions

What are some examples of potentially harmful conditions related to inflammation as mentioned in the text?

Hypersensitivity reactions to insect bites, drugs, contrast media in radiology

During inflammation, what causes endothelial cells to separate, allowing fluid + protein to enter tissue bed?

Inflammation

What is the delivery of leukocytes from the vessel lumen to the interstitium called?

Extravasation

What type of inflammation is characterized by outpouring of thin fluid such as serous effusion or blisters?

Serous inflammation

What is the outcome of acute inflammation that involves localized collections of pus?

Abscess formation

What is the term for the increased leukocyte count in the blood during systemic manifestations of inflammation?

Neutrophilia

Which phase of leukocyte emigration involves migration across the endothelium?

Diapedesis

What is the progression to chronic inflammation indicative of?

Fibrosis

What type of inflammation is characterized by leakage of fibrin and may lead to scar tissue or adhesions in body cavities?

Fibrinous inflammation

What outcome of acute inflammation involves substantial tissue destruction and occurs in tissues that do not regenerate?

Progression to chronic inflammation

During systemic manifestations, what leads to reduced volume of body fluid to be warmed?

Decreased secretion of vasopressin

Explore the fundamental concept of inflammation as a protective response to injury, including its role in the accumulation of fluid and leukocytes, initiation of the repair process, and potential harmful effects. Delve into the connection between inflammation and chronic diseases, hypersensitivity reactions, and the formation of disfiguring scars and adhesions.

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