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Questions and Answers
Which immunoglobulin is predominantly found in external secretions like tears and saliva?
Which immunoglobulin is predominantly found in external secretions like tears and saliva?
- IgG
- IgM
- IgD
- IgA (correct)
During an infection, which immunoglobulin is produced first?
During an infection, which immunoglobulin is produced first?
- IgM (correct)
- IgG
- IgD
- IgA
Which immunoglobulin crosses the placenta to provide passive immunity in newborns?
Which immunoglobulin crosses the placenta to provide passive immunity in newborns?
- IgD
- IgG (correct)
- IgM
- IgA
Which immunoglobulin is important in allergic reactions?
Which immunoglobulin is important in allergic reactions?
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Which immunoglobulin serves as antigen-specific receptors on B lymphocytes?
Which immunoglobulin serves as antigen-specific receptors on B lymphocytes?
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Study Notes
Immunoglobulin Classes
- IgG provides long-term immunity after vaccine or illness recovery and crosses the placenta to provide passive immunity in newborns
- Found in blood and extracellular fluid, IgG also provides lymphatic immunity
- IgA is present in external secretions such as tears and saliva, and is found in all mucous membranes
- IgA provides passive immunity for breastfed infants
- IgM is produced first during an infection, and IgG production follows afterwards
- IgM is found in blood and lymph
- IgD is an antigen-specific receptor on B lymphocytes
- IgE is associated with mast cells or basophils and plays a key role in allergic reactions
- Mast cells release histamine during allergic reactions
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