Understanding Depression and Antidepressants

What is the elimination half-life of citalopram?

Which SSRI has the least effect on the cytochrome P450 system?

What is the main clinical indication for SSRIs according to the text?

Which of the following is NOT a third-generation heterocyclic drug?

What is the half-life of venlafaxine's active metabolite, O-desmethyl-venlafaxine?

Why is dosing twice a day necessary for venlafaxine?

Which of the following is an emotional symptom of depression?

Which brain structure is primarily associated with anxiety in depression?

What is anhedonia most closely associated with in the brain?

Which of the following is NOT a biological symptom of depression mentioned in the text?

According to the DSM-V-TR criteria for a major depressive episode, how many symptoms must be present during a 2-week period?

Which of the following is a key feature of depression according to the text?

What is a potential adverse effect of the medication discussed?

What can occur if a MAOI is coadministered with an SSRI or venlafaxine?

What is a symptom of serotonin syndrome?

How long should one wait after stopping an SSRI before starting a MAOI?

What treatment approach is recommended for serotonin syndrome?

Why is a drug-free period of 2 weeks required when switching from a MAOI to another antidepressant?

Which antidepressant is known to have minimal effects on the cytochrome P450 enzyme system?

Which antidepressant is associated with modest increases in blood pressure in approximately 5% of patients at higher doses?

Which antidepressant does not cause sexual side effects like the SSRIs and venlafaxine?

Which antidepressant is tightly bound to protein and undergoes metabolism via CYP2D6 and CYP1A2?

Which antidepressant has been associated with a risk of seizures in 0.4% of patients at high doses?

Which antidepressant formulation is contraindicated in patients with a history of seizures?

Which medication inhibits the cytochrome P450 2D6 isoenzyme?

What receptor does mirtazapine block?

Which medication is relatively free of antimuscarinic side effects?

What is a common side effect of trazodone?

Which medication causes weight gain as a common side effect?

What mechanism of action does bupropion have on the cytochrome P450 2D6 isoenzyme?