Understanding Benign Neoplasms and Local Invasion in Pathology

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What is a characteristic of most benign tumors?

They form encapsulated masses

What is a distinguishing feature of leiomyoma of the uterus?

It lacks a well-developed capsule

Why do surgical pathologists carefully examine the margins of resected tumors?

To ensure they are devoid of cancer cells

What distinguishes the growth pattern of cancers from benign tumors?

Cancers grow by infiltration and destruction of surrounding tissue

What is a distinguishing feature of malignant tumors?

They do not develop well-defined capsules

What is hypertrophy?

An increase in the size of cells due to the synthesis of more proteins and cell organelles

What is hyperplasia?

An increase in the number of cells in an organ or tissue

What stimulates hypertrophy in the heart?

Chronic hemodynamic overload

What causes pathologic hyperplasia?

Excesses of hormones or growth factors acting on target cells

What is the main difference between hypertrophy and hyperplasia?

Hypertrophy refers to an increase in cell size, while hyperplasia refers to an increase in cell number

Learn about the features of benign neoplasms, including their localized growth, encapsulation, and lack of ability to infiltrate or metastasize. Explore the formation of capsules and the differences between benign and malignant tumors.

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