Podcast
Questions and Answers
What is the term used for the physiological process through which new blood vessels form from pre-existing vessels?
What is the term used for the physiological process through which new blood vessels form from pre-existing vessels?
- Invasion
- Angiogenesis (correct)
- Apoptosis
- Metastasis
What is the difference between cancer cells and normal cells?
What is the difference between cancer cells and normal cells?
- Cancer cells do not divide, while normal cells continue to grow and divide in a disorderly fashion.
- Normal cells grow, divide, and die in an orderly fashion, while cancer cells do not die and continue to grow and divide in a disorderly fashion. (correct)
- Cancer cells grow, divide, and die in an orderly fashion, while normal cells do not die and continue to grow and divide in a disorderly fashion.
- Normal cells do not divide, while cancer cells grow, divide, and die in an orderly fashion.
Which process provides the tumor cell with sufficient nutrients and oxygen supply for its growth?
Which process provides the tumor cell with sufficient nutrients and oxygen supply for its growth?
- Invasion
- Apoptosis
- Angiogenesis (correct)
- Metastasis
What is responsible for the removal of damaged or unnecessary cells through programmed cell death?
What is responsible for the removal of damaged or unnecessary cells through programmed cell death?
What is the direct extension and penetration by cancer cells into neighbouring tissues called?
What is the direct extension and penetration by cancer cells into neighbouring tissues called?
Which series of events cause a cell to divide into two daughter cells?
Which series of events cause a cell to divide into two daughter cells?
What is the phase of the cell cycle where DNA replication occurs?
What is the phase of the cell cycle where DNA replication occurs?
Which phase of the cell cycle involves the division of the cell's nucleus?
Which phase of the cell cycle involves the division of the cell's nucleus?
Which classification of cytotoxic drugs acts on all proliferating phases, including the G0 phase?
Which classification of cytotoxic drugs acts on all proliferating phases, including the G0 phase?
Which class of cytotoxic drugs directly acts on rapidly dividing cells and is highly toxic to cells?
Which class of cytotoxic drugs directly acts on rapidly dividing cells and is highly toxic to cells?
Which cytotoxic drug class disrupts DNA by forming covalent bonds between drug alkyl groups and DNA bases?
Which cytotoxic drug class disrupts DNA by forming covalent bonds between drug alkyl groups and DNA bases?
Which phase of the cell cycle is known as the growth phase?
Which phase of the cell cycle is known as the growth phase?
Which type of toxicity is a common side effect of most anticancer drugs?
Which type of toxicity is a common side effect of most anticancer drugs?
Which classification of cytotoxic drugs acts on a specific phase of the cell cycle?
Which classification of cytotoxic drugs acts on a specific phase of the cell cycle?
Which phase of the cell cycle do antimetabolites act on?
Which phase of the cell cycle do antimetabolites act on?
What is the mechanism of action of topoisomerase inhibitors?
What is the mechanism of action of topoisomerase inhibitors?
Which class of cytotoxic drugs disrupts the microtubule structure during mitosis?
Which class of cytotoxic drugs disrupts the microtubule structure during mitosis?
What is the mode of action of Vinca alkaloids like Vinblastine and Vincristine?
What is the mode of action of Vinca alkaloids like Vinblastine and Vincristine?
Which drug class binds to tubulin and prevents microtubule formation, resulting in dissolution of the mitotic spindle?
Which drug class binds to tubulin and prevents microtubule formation, resulting in dissolution of the mitotic spindle?
What is the mechanism of action of Topotecan and Irinotecan, which are specific to the S-phase?
What is the mechanism of action of Topotecan and Irinotecan, which are specific to the S-phase?
Which drug causes bone marrow suppression and serious hypersensitivity reactions, necessitating premedication with dexamethasone and diphenhydramine?
Which drug causes bone marrow suppression and serious hypersensitivity reactions, necessitating premedication with dexamethasone and diphenhydramine?
Which drug is specific to late S & early G2 phase and inhibits the resealing step of DNA replication?
Which drug is specific to late S & early G2 phase and inhibits the resealing step of DNA replication?
What is the primary toxic effect associated with Irinotecan?
What is the primary toxic effect associated with Irinotecan?
Which drug acts by preventing the assembly of tubulin and preventing microtubule formation?
Which drug acts by preventing the assembly of tubulin and preventing microtubule formation?
What is the dose-limiting toxicity associated with Topotecan?
What is the dose-limiting toxicity associated with Topotecan?