12 Questions
What percentage of WBC in blood do polymorphonuclear leukocytes make up?
70%
Which type of leukocytes are the first cells to arrive at a site of inflammation?
Neutrophils
What do neutrophils contain in their granules?
Bactericidal proteins
What do neutrophils mainly attack?
Antibody-labeled bacteria
What is the lifespan of neutrophils?
1 day
What can the formation of pus caused by killed bacteria and neutrophils lead to?
Damage to healthy tissue
What do neutrophils secrete that recruit more immune cells?
Cytokines
What condition occurs during acute bacterial infections?
Neutrophilia
What is the cause of neutrophilia?
Increased mobilization and production of G-CSF
What is the function of neutrophils in attacking bacteria?
To secrete toxic chemicals
What is the size of polymorphonuclear leukocytes?
12µm
Which type of leukocytes contain histamine in their granules?
Basophils
Study Notes
- Polymorphonuclear leukocytes are 12µm and make up 70% of WBC in blood.
- Neutrophils contain granules with bactericidal proteins.
- Neutrophils are the first cells to arrive at a site of inflammation.
- Neutrophils attack bacteria and secrete toxic chemicals.
- Neutrophils have a short lifespan of approximately 1 day.
- Killed bacteria and neutrophils form pus which can cause damage to healthy tissue.
- Neutrophils secrete inflammatory mediators that recruit more immune cells.
- Neutrophilia occurs during acute bacterial infections.
- Neutrophilia is due to increased mobilization and production of G-CSF.
- Neutrophils mainly attack antibody-labeled bacteria.
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