UBD: Humoral Immunity Deficiency

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5 Questions

What is the primary characteristic of UBD?

Humoral immunity deficiency

Which of the following is a common feature of UBD?

Increased susceptibility to bacterial infections

What is the cause of deficiency seen in UBD?

B cell defects

What is a notable feature related to growth and development in UBD?

Delayed growth and development

What is a pathogenesis factor of UBD?

Block of differentiation & development of B cells

Study Notes

UBD Characteristics

  • UBD is characterized by humoral immunity deficiency
  • 50-60% of UBD cases involve B cell defects
  • B cell defects lead to deficiency of Ig and antibody

Clinical Features

  • Increased susceptibility to bacteria, enterovirus, and intestine parasites
  • Delayed growth and development
  • Increased incidence of autoimmune diseases
  • Increased incidence of malignant tumors
  • Reduced numbers of peripheral blood B cells
  • Absent or reduced levels of Ig

Pathogenesis of UBD

  • Block of differentiation and development of B cells
  • Reduced function of Th cells

Learn about UBD, a humoral immunity deficiency characterized by B cell defects, Ig deficiency, and increased susceptibility to various infections and diseases.

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