12 Questions
Which class of antibodies accounts for 80% of all antibodies?
IgG
What type of immunity does maternal IgG provide to the fetus during embryonic development?
Passive immunity
Which antibodies cause hemolytic disease of the newborn in Rh-negative mothers?
IgG antibodies
What is the role of IgE in allergic responses?
It causes inflammation by attaching to basophils and mast cells
Which class of antibody is found on the surfaces of B cells and can bind antigens, sensitizing the B cell involved?
IgD
What is the first class of antibody secreted after encountering an antigen?
IgM
Which antibodies are responsible for agglutination of incompatible blood types?
IgM antibodies
Where is IgA primarily found?
In glandular secretions
What do epithelial cells do to IgA before secreting it onto the epithelial surface?
They attach a secretory piece
Which class of antibodies provides resistance against viruses, bacteria, and bacterial toxins?
IgG
What is the main function of IgA?
To attack pathogens before they gain access to internal tissues
Which antibodies attach to basophils and mast cells, causing inflammation and playing a role in allergic responses?
IgE antibodies
Study Notes
- IgG is the largest and most diverse class of antibodies, accounting for 80% of all antibodies
- IgG antibodies provide resistance against viruses, bacteria, and bacterial toxins
- Maternal IgG provides passive immunity to the fetus during embryonic development
- Anti-Rh antibodies produced by Rh-negative mothers are also IgG antibodies and cause hemolytic disease of the newborn
- IgE attaches to basophils and mast cells, causing inflammation and playing a role in allergic responses
- IgD is found on the surfaces of B cells and can bind antigens, sensitizing the B cell involved
- IgM is the first class of antibody secreted after encountering an antigen and can attack bacteria insensitive to IgG
- Anti-A and anti-B antibodies responsible for agglutination of incompatible blood types are IgM antibodies
- IgA is primarily found in glandular secretions and attacks pathogens before they gain access to internal tissues
- Epithelial cells absorb IgA from the blood and attach a secretory piece before secreting it onto the epithelial surface.
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