Immunology -Structure and Classes of Antibodies 863
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Questions and Answers

What is the approximate percentage of antibodies in plasma?

  • 10%
  • 25%
  • 35% (correct)
  • 50%
  • Which type of protein are antibodies?

  • Enzymes
  • Hormones
  • Soluble proteins (correct)
  • Structural proteins
  • What is the structure of antibodies?

  • Linear chains
  • Circular chains
  • Y-shaped structure (correct)
  • Helical structure
  • Which segments of the heavy chains determine the class of the antibody?

    <p>Constant segments</p> Signup and view all the answers

    How many classes of antibodies are there?

    <p>5</p> Signup and view all the answers

    What determines the specificity of an antibody?

    <p>Amino acid sequence of the variable segments</p> Signup and view all the answers

    How do small differences in the structure of the variable segments affect the antibody's function?

    <p>They make the antibody more specific</p> Signup and view all the answers

    How many types of antibodies can B cells produce?

    <p>100 million</p> Signup and view all the answers

    What are the antigen-binding sites?

    <p>The variable segments</p> Signup and view all the answers

    What is the function of transport globulins?

    <p>Transport lipids and hormones</p> Signup and view all the answers

    Which class of antibody is responsible for allergic reactions?

    <p>IgE</p> Signup and view all the answers

    What is the function of IgA antibodies?

    <p>Protect mucosal surfaces</p> Signup and view all the answers

    Study Notes

    • Antibodies are soluble proteins that attack foreign proteins and pathogens.
    • They account for approximately 35% of the proteins in plasma.
    • Antibodies are a type of globulin, along with transport globulins.
    • Antibodies have a Y-shaped structure consisting of heavy and light chains.
    • The constant segments of the heavy chains determine the class of the antibody.
    • There are five classes of antibodies: IgG, IgE, IgD, IgM, and IgA.
    • The specificity of an antibody depends on the amino acid sequence of the variable segments of the light and heavy chains.
    • Small differences in the structure of the variable segments affect the precise shape of the antigen-binding site.
    • B cells can produce an estimated 100 million types of antibodies, each with a different specificity.
    • The antigen-binding sites are the free tips of the variable segments of the antibody molecule.

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