Types of Proteomics: Expression Proteomics

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Questions and Answers

What is the focus of expression proteomics?

  • Studying qualitative and quantitative expression of total proteins (correct)
  • Analyzing protein-protein interactions in membranes
  • Understanding three-dimensional shapes of proteins
  • Exploring protein functions and molecular mechanisms within cells

Which technology is mainly used for structure determination in structural proteomics?

  • Mass spectrometry
  • NMR spectroscopy
  • X-ray crystallography (correct)
  • Polymerase chain reaction

What does functional proteomics focus on?

  • Studying qualitative and quantitative expression of total proteins
  • Protein functions and molecular mechanisms within cells (correct)
  • Analyzing protein-protein interactions in membranes
  • Understanding three-dimensional shapes of proteins

In which type of proteomics are abnormal cells compared to normal cells?

<p>Expression proteomics (B)</p> Signup and view all the answers

What does structural proteomics help to understand?

<p>Three-dimensional shape and structural complexities of functional proteins (A)</p> Signup and view all the answers

Which type of proteomics focuses on investigating protein patterns in tumor tissue samples?

<p>Expression proteomics (C)</p> Signup and view all the answers

What is the clear liquid left as supernatant when blood is centrifuged in the presence of heparin?

<p>Plasma (C)</p> Signup and view all the answers

What is the main limitation of studying the plasma proteome mentioned in the text?

<p>Difficulty accessing relative protein abundance (A)</p> Signup and view all the answers

What type of body fluids have been investigated for proteomics due to the limitations of studying plasma proteome?

<p>Urine, seminal plasma, tear fluid, cerebrospinal fluid (B)</p> Signup and view all the answers

Which of the following regulates gene expression in a hormonal-independent manner?

<p>Fatty acids (D)</p> Signup and view all the answers

In which cell lines did butyrate affect the expression of genes involved in the regulation of cell apoptosis?

<p>Colorectal cancer cell lines (B)</p> Signup and view all the answers

Which signaling molecules are mentioned as carrying out the biological functions of lipids?

<p>Diacylglycerol, ceramides, eicosanoids (D)</p> Signup and view all the answers

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