Expression Proteomics Overview

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Questions and Answers

What is the term used for the clear liquid left after centrifuging blood in the presence of heparin?

  • Sediment
  • Plasma (correct)
  • Supernatant
  • Serum

How many different phenotypes can mutations in TP53 produce?

  • 5
  • 3
  • 11 (correct)
  • 7

What is the main limitation of the plasma proteome mentioned in the text?

  • Presence of too few proteins
  • Ease of identifying biomarkers
  • Difficulty in accessing the relative abundance of proteins (correct)
  • Low protein content

Which body fluids have been investigated instead of plasma due to challenges with plasma proteome?

<p>Urine, seminal plasma, tear fluid, and cerebrospinal fluid (B)</p> Signup and view all the answers

What happens to proteins in plasma when there is no anticoagulant present?

<p>They clot (B)</p> Signup and view all the answers

How many genes can cause a progressive disorder according to the text?

<p>11 (B)</p> Signup and view all the answers

What is the primary focus of expression proteomics?

<p>Studying the qualitative and quantitative expression of total proteins under different conditions (C)</p> Signup and view all the answers

Which technology is mainly used in structural proteomics for structure determination?

<p>X-ray crystallography (C)</p> Signup and view all the answers

What is the main goal of functional proteomics?

<p>Understanding protein functions and cellular interactions (B)</p> Signup and view all the answers

How can expression proteomics help in understanding diseases?

<p>By comparing normal and diseased cell protein expression (A)</p> Signup and view all the answers

Which type of proteomics gives detailed information about protein complexes within cellular organelles?

<p>Structural proteomics (B)</p> Signup and view all the answers

What is the main purpose of investigating protein interactions in functional proteomics?

<p>To understand protein functions and molecular mechanisms (D)</p> Signup and view all the answers

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