Expression Proteomics Overview

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What is the term used for the clear liquid left after centrifuging blood in the presence of heparin?

Plasma

How many different phenotypes can mutations in TP53 produce?

11

What is the main limitation of the plasma proteome mentioned in the text?

Difficulty in accessing the relative abundance of proteins

Which body fluids have been investigated instead of plasma due to challenges with plasma proteome?

Urine, seminal plasma, tear fluid, and cerebrospinal fluid

What happens to proteins in plasma when there is no anticoagulant present?

They clot

How many genes can cause a progressive disorder according to the text?

11

What is the primary focus of expression proteomics?

Studying the qualitative and quantitative expression of total proteins under different conditions

Which technology is mainly used in structural proteomics for structure determination?

X-ray crystallography

What is the main goal of functional proteomics?

Understanding protein functions and cellular interactions

How can expression proteomics help in understanding diseases?

By comparing normal and diseased cell protein expression

Which type of proteomics gives detailed information about protein complexes within cellular organelles?

Structural proteomics

What is the main purpose of investigating protein interactions in functional proteomics?

To understand protein functions and molecular mechanisms

Explore the field of expression proteomics which is used to analyze the qualitative and quantitative expression of total proteins under different conditions. Learn how this technique helps in identifying proteins responsible for stress, disease states, and abnormal cell patterns.

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