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Expression Proteomics Overview

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Questions and Answers

What is the term used for the clear liquid left after centrifuging blood in the presence of heparin?

Sediment

Plasma (correct)

Supernatant

Serum

How many different phenotypes can mutations in TP53 produce?

11 (correct)

What is the main limitation of the plasma proteome mentioned in the text?

Presence of too few proteins

Ease of identifying biomarkers

Difficulty in accessing the relative abundance of proteins (correct)

Low protein content

Which body fluids have been investigated instead of plasma due to challenges with plasma proteome?

Urine, seminal plasma, tear fluid, and cerebrospinal fluid Signup and view all the answers

What happens to proteins in plasma when there is no anticoagulant present?

They clot Signup and view all the answers

How many genes can cause a progressive disorder according to the text?

11 Signup and view all the answers

What is the primary focus of expression proteomics?

Studying the qualitative and quantitative expression of total proteins under different conditions Signup and view all the answers

Which technology is mainly used in structural proteomics for structure determination?

X-ray crystallography Signup and view all the answers

What is the main goal of functional proteomics?

Understanding protein functions and cellular interactions Signup and view all the answers

How can expression proteomics help in understanding diseases?

By comparing normal and diseased cell protein expression Signup and view all the answers

Which type of proteomics gives detailed information about protein complexes within cellular organelles?

Structural proteomics Signup and view all the answers

What is the main purpose of investigating protein interactions in functional proteomics?

To understand protein functions and molecular mechanisms Signup and view all the answers