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Expression Proteomics Study Quiz

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Questions and Answers

What is the clear liquid left after centrifuging blood in the presence of heparin called?

Serum

Cerebrospinal fluid

Plasma (correct)

Urine

Why is it difficult to access the relative abundance of a particular protein in plasma proteome?

High number of proteins (correct)

Easy identification of biomarkers

Low number of proteins

Use of anticoagulants

What is the major limitation of plasma proteome mentioned in the text?

Anticoagulants are ineffective

Difficulty in accessing protein abundance (correct)

Identification of biomarkers is easy

Small number of proteins

In what body fluid has proteomics been investigated due to difficulties with plasma proteome?

Tear fluid Signup and view all the answers

How is the clear liquid containing soluble proteins obtained after centrifuging blood without an anticoagulant referred to?

Serum Signup and view all the answers

What is the result of mutations in TP53 according to the text?

11 different phenotypes of cancer Signup and view all the answers

What does expression proteomics primarily focus on?

Studying the qualitative and quantitative expression of total proteins under different conditions Signup and view all the answers

Which technology is NOT typically used in structural proteomics for structure determination?

Mass spectrometry Signup and view all the answers

What is the main goal of functional proteomics?

Understanding protein functions and molecular mechanisms within cells Signup and view all the answers

Which type of proteomics would be most useful in identifying the specific protein responsible for a diseased state?

Expression proteomics Signup and view all the answers

How does expression proteomics differ from functional proteomics?

Expression proteomics studies protein expression under different conditions, while functional proteomics looks at protein functions and molecular mechanisms within cells. Signup and view all the answers

What role do technologies like X-ray crystallography and NMR spectroscopy play in proteomic studies?

Determining protein structure in structural proteomics Signup and view all the answers