Expression Proteomics Study Quiz

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Questions and Answers

What is the clear liquid left after centrifuging blood in the presence of heparin called?

  • Serum
  • Cerebrospinal fluid
  • Plasma (correct)
  • Urine

Why is it difficult to access the relative abundance of a particular protein in plasma proteome?

  • High number of proteins (correct)
  • Easy identification of biomarkers
  • Low number of proteins
  • Use of anticoagulants

What is the major limitation of plasma proteome mentioned in the text?

  • Anticoagulants are ineffective
  • Difficulty in accessing protein abundance (correct)
  • Identification of biomarkers is easy
  • Small number of proteins

In what body fluid has proteomics been investigated due to difficulties with plasma proteome?

<p>Tear fluid (D)</p> Signup and view all the answers

How is the clear liquid containing soluble proteins obtained after centrifuging blood without an anticoagulant referred to?

<p>Serum (A)</p> Signup and view all the answers

What is the result of mutations in TP53 according to the text?

<p>11 different phenotypes of cancer (C)</p> Signup and view all the answers

What does expression proteomics primarily focus on?

<p>Studying the qualitative and quantitative expression of total proteins under different conditions (A)</p> Signup and view all the answers

Which technology is NOT typically used in structural proteomics for structure determination?

<p>Mass spectrometry (B)</p> Signup and view all the answers

What is the main goal of functional proteomics?

<p>Understanding protein functions and molecular mechanisms within cells (D)</p> Signup and view all the answers

Which type of proteomics would be most useful in identifying the specific protein responsible for a diseased state?

<p>Expression proteomics (D)</p> Signup and view all the answers

How does expression proteomics differ from functional proteomics?

<p>Expression proteomics studies protein expression under different conditions, while functional proteomics looks at protein functions and molecular mechanisms within cells. (C)</p> Signup and view all the answers

What role do technologies like X-ray crystallography and NMR spectroscopy play in proteomic studies?

<p>Determining protein structure in structural proteomics (C)</p> Signup and view all the answers

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