Types of Necrosis and Inflammatory Response Quiz
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Questions and Answers

What is the consequence of the release of cellular contents during necrosis?

  • It inhibits the immune system.
  • It triggers an inflammatory response. (correct)
  • It enhances cellular communication.
  • It promotes tissue regeneration.
  • Which type of necrosis is characterized by the preservation of tissue architecture for a period?

  • Liquefaction Necrosis
  • Coagulative Necrosis (correct)
  • Fat Necrosis
  • Caseous Necrosis
  • What is the typical cause of Coagulative Necrosis?

  • Hypoxia
  • Hyperplasia
  • Ischemia (correct)
  • Inflammation
  • Which organ is commonly affected by Coagulative Necrosis?

    <p>Heart</p> Signup and view all the answers

    What effect does Coagulative Necrosis have on cellular proteins?

    <p>Denaturation of cellular proteins</p> Signup and view all the answers

    What are the common examples of morphologic changes associated with reversible cell injury?

    <p>Hydropic Change, Fatty Change, Hyaline Change, Mucoid Change</p> Signup and view all the answers

    What initiates structural and functional alterations in cells according to the text?

    <p>Cellular injury</p> Signup and view all the answers

    Which of the following agents is listed as a cause of cell injury in the text?

    <p>Psychogenic diseases</p> Signup and view all the answers

    What type of response is required for cell injury to be considered reversible according to the text?

    <p>Non-lethal</p> Signup and view all the answers

    Which organelle is involved in energy production in cells as mentioned in the text?

    <p>Mitochondria</p> Signup and view all the answers

    What is the main cause of cellular injury according to the text?

    <p>Hypoxia &amp; Ischemia</p> Signup and view all the answers

    What is dysplasia often accompanied by?

    <p>Metaplasia</p> Signup and view all the answers

    What type of cells does dysplasia occur most often in?

    <p>Epithelial cells</p> Signup and view all the answers

    What is the hallmark of epithelial dysplasia?

    <p>Cellular proliferation and cytologic changes</p> Signup and view all the answers

    Which organelle is severely damaged in irreversible cell injury causing a loss of ATP production?

    <p>Mitochondria</p> Signup and view all the answers

    What nuclear change occurs in irreversible cell injury where there is complete dissolution of the nucleus?

    <p>Karyolysis</p> Signup and view all the answers

    What do large vacuoles containing cellular debris indicate in cytoplasmic changes?

    <p>Cellular degradation</p> Signup and view all the answers

    Which of the following infectious agents can directly damage cells through invasion, toxin production, or induction of inflammatory responses?

    <p>Viruses</p> Signup and view all the answers

    In autoimmune diseases, the immune system mistakenly targets and attacks healthy cells, leading to:

    <p>Apoptosis of affected cells</p> Signup and view all the answers

    Which of the following is an example of hypersensitivity reactions that can cause tissue damage through immune complex deposition or direct cell destruction?

    <p>Type I hypersensitivity</p> Signup and view all the answers

    Genetic mutations can contribute to cell injury by leading to malfunctioning proteins, disrupted signaling pathways, or abnormal:

    <p>Cell cycle regulation</p> Signup and view all the answers

    Lack of essential nutrients like vitamins and minerals can impair cellular metabolism and lead to:

    <p>Cell dysfunction or death</p> Signup and view all the answers

    Reduced blood flow limiting oxygen supply can lead to energy depletion, mitochondrial dysfunction, and eventual cell injury or death in a condition known as:

    <p>Anoxia</p> Signup and view all the answers

    What is the primary effect of anoxia on cellular metabolism?

    <p>Rapid ATP depletion</p> Signup and view all the answers

    Which type of radiation is known to cause DNA damage by generating free radicals?

    <p>Ionizing Radiation</p> Signup and view all the answers

    How does prolonged chronic inflammation contribute to tissue damage and cell injury?

    <p>Continuous release of inflammatory mediators</p> Signup and view all the answers

    In autoimmune inflammation, what do immune cells target and attack?

    <p>Healthy tissues</p> Signup and view all the answers

    What impact does chronic stress have on the immune system?

    <p>Dysregulation of the immune system</p> Signup and view all the answers

    What contributes to aging-related cell injury and dysfunction over time?

    <p>Accumulation of cellular damage</p> Signup and view all the answers

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