Types of Necrosis and Inflammatory Response Quiz

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Questions and Answers

What is the consequence of the release of cellular contents during necrosis?

  • It inhibits the immune system.
  • It triggers an inflammatory response. (correct)
  • It enhances cellular communication.
  • It promotes tissue regeneration.

Which type of necrosis is characterized by the preservation of tissue architecture for a period?

  • Liquefaction Necrosis
  • Coagulative Necrosis (correct)
  • Fat Necrosis
  • Caseous Necrosis

What is the typical cause of Coagulative Necrosis?

  • Hypoxia
  • Hyperplasia
  • Ischemia (correct)
  • Inflammation

Which organ is commonly affected by Coagulative Necrosis?

<p>Heart (D)</p> Signup and view all the answers

What effect does Coagulative Necrosis have on cellular proteins?

<p>Denaturation of cellular proteins (D)</p> Signup and view all the answers

What are the common examples of morphologic changes associated with reversible cell injury?

<p>Hydropic Change, Fatty Change, Hyaline Change, Mucoid Change (A)</p> Signup and view all the answers

What initiates structural and functional alterations in cells according to the text?

<p>Cellular injury (C)</p> Signup and view all the answers

Which of the following agents is listed as a cause of cell injury in the text?

<p>Psychogenic diseases (B)</p> Signup and view all the answers

What type of response is required for cell injury to be considered reversible according to the text?

<p>Non-lethal (A)</p> Signup and view all the answers

Which organelle is involved in energy production in cells as mentioned in the text?

<p>Mitochondria (B)</p> Signup and view all the answers

What is the main cause of cellular injury according to the text?

<p>Hypoxia &amp; Ischemia (D)</p> Signup and view all the answers

What is dysplasia often accompanied by?

<p>Metaplasia (D)</p> Signup and view all the answers

What type of cells does dysplasia occur most often in?

<p>Epithelial cells (D)</p> Signup and view all the answers

What is the hallmark of epithelial dysplasia?

<p>Cellular proliferation and cytologic changes (D)</p> Signup and view all the answers

Which organelle is severely damaged in irreversible cell injury causing a loss of ATP production?

<p>Mitochondria (A)</p> Signup and view all the answers

What nuclear change occurs in irreversible cell injury where there is complete dissolution of the nucleus?

<p>Karyolysis (A)</p> Signup and view all the answers

What do large vacuoles containing cellular debris indicate in cytoplasmic changes?

<p>Cellular degradation (B)</p> Signup and view all the answers

Which of the following infectious agents can directly damage cells through invasion, toxin production, or induction of inflammatory responses?

<p>Viruses (A)</p> Signup and view all the answers

In autoimmune diseases, the immune system mistakenly targets and attacks healthy cells, leading to:

<p>Apoptosis of affected cells (B)</p> Signup and view all the answers

Which of the following is an example of hypersensitivity reactions that can cause tissue damage through immune complex deposition or direct cell destruction?

<p>Type I hypersensitivity (B)</p> Signup and view all the answers

Genetic mutations can contribute to cell injury by leading to malfunctioning proteins, disrupted signaling pathways, or abnormal:

<p>Cell cycle regulation (C)</p> Signup and view all the answers

Lack of essential nutrients like vitamins and minerals can impair cellular metabolism and lead to:

<p>Cell dysfunction or death (C)</p> Signup and view all the answers

Reduced blood flow limiting oxygen supply can lead to energy depletion, mitochondrial dysfunction, and eventual cell injury or death in a condition known as:

<p>Anoxia (D)</p> Signup and view all the answers

What is the primary effect of anoxia on cellular metabolism?

<p>Rapid ATP depletion (B)</p> Signup and view all the answers

Which type of radiation is known to cause DNA damage by generating free radicals?

<p>Ionizing Radiation (C)</p> Signup and view all the answers

How does prolonged chronic inflammation contribute to tissue damage and cell injury?

<p>Continuous release of inflammatory mediators (C)</p> Signup and view all the answers

In autoimmune inflammation, what do immune cells target and attack?

<p>Healthy tissues (C)</p> Signup and view all the answers

What impact does chronic stress have on the immune system?

<p>Dysregulation of the immune system (D)</p> Signup and view all the answers

What contributes to aging-related cell injury and dysfunction over time?

<p>Accumulation of cellular damage (A)</p> Signup and view all the answers

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