Types of Macromolecules in Biology
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Questions and Answers

Which of the following statements about proteins is correct?

  • Proteins serve primarily as energy storage molecules.
  • Proteins are formed by glycosidic bonds between amino acids.
  • Proteins are composed of fatty acid subunits.
  • Proteins must be folded correctly to function optimally. (correct)
  • Which type of bond links nucleotide monomers in nucleic acids?

  • Phosphodiester bonds (correct)
  • Peptide bonds
  • Hydrogen bonds
  • Glycosidic bonds
  • What is the main function of carbohydrates in living organisms?

  • Energy for metabolism (correct)
  • Carrying genetic information
  • Facilitating chemical reactions
  • Providing structural support
  • Which of the following accurately describes the function of lipids?

    <p>Store energy and act as signaling molecules (D)</p> Signup and view all the answers

    Which type of metabolism is characterized by building molecules and requires an input of ATP?

    <p>Anabolism (A)</p> Signup and view all the answers

    How do enzymes lower the activation energy of a reaction?

    <p>By stabilizing the transition state (B)</p> Signup and view all the answers

    What occurs during the termination step of enzyme catalysis?

    <p>Products are released as they have lower bond affinity. (A)</p> Signup and view all the answers

    In what scenario would an enzyme not function properly?

    <p>When the enzyme is exposed to extreme pH or temperature (A)</p> Signup and view all the answers

    What characterizes the cell membranes of animal cells?

    <p>Dynamic, with a phospholipid bilayer (A)</p> Signup and view all the answers

    What type of molecules diffuse across a cell membrane most easily?

    <p>Small nonpolar molecules (A)</p> Signup and view all the answers

    How do aquaporins facilitate water movement across cell membranes?

    <p>By providing a channel specific for water molecules (B)</p> Signup and view all the answers

    Which of the following best describes exocytosis?

    <p>Transport of materials out of the cell via vesicles (D)</p> Signup and view all the answers

    What defines eukaryotic cells in contrast to prokaryotic cells?

    <p>Eukaryotic cells are characterized by compartmentalized organelles (B)</p> Signup and view all the answers

    What role do lysosomes play in the cell?

    <p>Break down macromolecules in an acidic environment (A)</p> Signup and view all the answers

    Flashcards

    Types of Macromolecules

    Four major organic molecules essential for life: proteins, nucleic acids, carbohydrates, and lipids.

    Proteins

    Macromolecules that perform critical reactions and provide structure in cells; composed of amino acids linked by peptide bonds.

    Nucleic Acids

    Macromolecules that carry genetic information and energy carriers; composed of nucleotides linked by phosphodiester bonds.

    Carbohydrates

    Sugars that provide energy for metabolism; composed of monosaccharides linked by glycosidic bonds.

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    Lipids

    Hydrophobic molecules that serve as energy storage, signaling components (steroids), and structural bases (phospholipids) for cell membranes.

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    Metabolism

    The set of chemical reactions that convert molecules and transfer energy to sustain life.

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    Catabolism

    Metabolic pathways that break down molecules into smaller units, releasing energy (ATP).

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    Anabolism

    Metabolic pathways that build molecules from smaller units, requiring energy input (ATP).

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    Enzymes

    Biological catalysts that speed up chemical reactions in cells, highly specific for substrates.

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    Induced Fit Model

    Enzyme wraps around substrates, optimizing their orientation for reaction in the active site.

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    Active Site

    The specific region on an enzyme where substrate molecules bind and undergo a chemical reaction.

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    Cell Membrane Components

    Cell membranes consist of phospholipids, proteins, and carbohydrates, forming a selective barrier.

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    Diffusion

    Movement of molecules from an area of higher concentration to an area of lower concentration across a membrane.

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    Osmosis

    The movement of water across a semipermeable membrane from a region of lower solute concentration to higher solute concentration.

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    Eukaryotic Cells

    Cells characterized by a nucleus containing genetic material and membrane-bound organelles; complex structure.

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    Study Notes

    Types of Macromolecules

    • Four major organic molecules are essential for life processes: proteins, nucleic acids, carbohydrates, and lipids.
    • Molecules are primarily large polymers composed of repeated simpler units (monomers/subunits) connected by covalent bonds.

    Proteins

    • Function: crucial for critical reactions, cell structure, and support
    • Monomer subunit: amino acid subunits
    • Bond type: peptide bonds (carboxyl and amino group)

    Nucleic Acids

    • Function: energy carriers and genetic information storage in nucleotides.
    • Monomer subunit: nucleotide monomers
    • Bond type: phosphodiester bonds

    Carbohydrates (Sugars)

    • Function: energy for metabolism
    • Monomer subunit: monosaccharides (linear/cyclic molecules with 5-6 atoms)
    • Bond type: glycosidic bonds
    • Additional notes: monosaccharides form complex carbohydrates (disaccharides and polysaccharides)

    Lipids

    • Shared feature: hydrophobic components
    • Function of fats: energy storage
    • Function of steroids: components of animal plasma membranes, and signalling molecules
    • Function of phospholipids: major component of cell membranes

    Metabolism and Enzymes

    • Metabolism: chemical reactions converting molecules and transferring energy in living organisms.
    • Two types of metabolism:
      • Catabolism: breaking down molecules into smaller units, produces ATP.
      • Anabolism: building molecules from smaller units, requires ATP.
    • Enzymes: biological catalysts that speed up chemical reactions.
      • Help overcome hurdles of reactant collisions and sufficient kinetic energy.
      • Bring substrates together at the active site (substrate binding site)
      • Help substrates collide with the correct orientation for reactions.
      • Lower activation energy: stabilize transition state

    Enzymes (Continued)

    • Enzymes catalyse a single reaction with high specificity.
    • Transition state: intermediate unstable state during reaction.
    • Activation state: energy required for a reaction to occur.
    • Enzymes lower activation energy to facilitate the reaction.
    • Three-step process of catalysis:
      • Initiation: reactants bind to the active site.
      • Transition state: interactions between enzyme and substrate.
      • Termination: products have lower affinity for the active site, and molecules leave.
    • Know Catalyzed vs Uncatalyzed Reaction Curves
      • AG: Represents change in free energy.
      • Enzyme Saturation: Active sites are all filled.
      • An enzyme's activity is sensitive to conditions. Misfolded from heat or cold.
      • Range of pH that enzymes work in
    • Enzyme Regulation
    • Noncovalent modifications (molecules that bind enzyme somewhere to change its conformation).
    • Competitive inhibition: inhibitor molecule mimics substrate, blocking active site.
    • Allosteric regulation: molecule binds somewhere other than the active site, altering shape of the enzyme and thus changing its activity or location in the cell.
    • Inhibition: enzyme's active site not available, enzyme is no longer active.

    Cell Membranes

    • Selective barrier, helps maintain homeostasis
    • Animal cells have only cell membrane, plants have cell membrane and cell wall.
    • Three major components:
      • Phospholipids are major component of cell membrane
      • Proteins
      • Carbohydrates
    • Cell membrane is amphipathic: hydrophilic and hydrophobic components; spontaneously form structures in water.
    • Properties affect how molecules move across membrane:
      • Miciles
      • Bilayer
      • Small nonpolar molecules (CO2)
      • Small uncharged polar molecules (water, glycerol)
      • Large uncharged polar molecules (glucose, amino acids)
      • lons (sodium ions)

    Movement Across Cell Membranes

    • Simple diffusion: solutes move from high to low concentration.
    • Osmosis: the movement of water across a membrane.
    • Isotonic, Hypertonic, Hypotonic

    Membrane Proteins

    • Membrane proteins assist in facilitated diffusion.
    • Channels and carriers (passive transport)
    • Active transport: requires ATP

    Eukaryotic Cells

    • Nucleus: contains genetic material
    • Organelles: specialized compartments for specific functions.
    • Endomembrane system (ER, Golgi, lysosomes): interconnected network for protein synthesis, modification, and transport.
    • Cytoskeleton: helps maintain cell shape and facilitate movement.
      • Endocytosis
      • Exocytosis

    Evolution of Multicellularity

    • Unicellular eukaryotes stick together to form colonies
    • Complex multicellular organisms have: cell adhesion, cell communication, and complex patterns of cellular and tissue differentiation.
    • Cadherins: proteins that enable cells to stick to each other.
    • Integrins: link cells to the extracellular matrix.
    • Pectin: a plant polysaccharide for adhesion.

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    Description

    Explore the four major types of macromolecules essential for life: proteins, nucleic acids, carbohydrates, and lipids. This quiz will assess your understanding of their functions, monomer units, and bonding types. Test your knowledge on how these organic molecules contribute to biological processes!

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